Incidence of thyroid diseases: Results from the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil)
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2021 |
| Outros Autores: | , , , , , , , , , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
| Texto Completo: | https://www.arca.fiocruz.br/handle/icict/46989 |
Resumo: | Universidade de São Paulo, São Paulo. Centro de Pesquisa Clínica e Epidemiológica. São Paulo, SP, Brasil. |
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Benseñor, Isabela M.Sgarbi, José AugustoJanovsky, Carolina Castro Porto SilvaPittita, Bianca AlmeidaDiniz, Maria de Fátima Haueisen SanderAlmeida, Maria da Conceição Chagas deAlvim, Sheila MariaBarreto, Sandhi M.Giatti, LuanaDuncan, Bruce B.Schmidt, Maria InêsFonseca, Maria de Jesus M.Griep, Rosane H.Molina, Maria del Carmen B.Mill, João GeraldoSantos, Itamar de SouzaGoulart, Alesandra C.Lotudo, Paulo A.2021-04-30T19:21:39Z2021-04-30T19:21:39Z2021BENSEÑOR, Isabela M. et al. Incidence of thyroid diseases: Results from the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil). Arch Endocrinol Metab. Online ahead of print, 11p, 2021.2359-3997https://www.arca.fiocruz.br/handle/icict/4698910.20945/2359-39970000003482359-4292engSociedade Brasileira de Endocrinologia e MetabologiaOvert thyroid diseasesELSA-BrasilDoenças da tireoide subclínicaHipertiroidismoHipotireoidismoIncidênciaOvert thyroid diseasesSubclinical thyroid diseasesHyperthyroidismHypothyroidismIncidenceELSA-BrasilIncidence of thyroid diseases: Results from the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil)info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidade de São Paulo, São Paulo. Centro de Pesquisa Clínica e Epidemiológica. São Paulo, SP, Brasil.Faculdade de Medicina de Marília. Divisão de Endocrinologia. Marília, SP, Brasil.Universidade de São Paulo. São Paulo. Centro de Pesquisa Clínica e Epidemiológica. São Paulo, SP, Brasil.Universidade Federal de São Paulo. Departamento de Medicina Preventiva. São Paulo, SP, Brasil.Universidade Federal de Minas Gerais. Faculdade de Medicina. Belo Horizonte, MG, Brasil.Fundação Oswaldo Cruz. Instituto Gonçalo Muniz. Belo Horizonte, MG, Brasil.Universidade Federal da Bahia. Instituto de Saúde Coletiva. Salvador, BA, Brasil.Universidade Federal de Minas Gerais. Medicina Preventiva. Belho Horizonte, MG, Brasil.Universidade Federal de Minas Gerais. Medicina Preventiva. Belho Horizonte, MG, Brasil.Universidade Federal do Rio Grande do Sul. Programa de Pós-Graduação em Epidemiologia. Porto Alegre, RS, Brasil.Universidade Federal do Rio Grande do Sul. Programa de Pós-Graduação em Epidemiologia. Porto Alegre, RS, Brasil.Fundação Oswaldo Cruz. Escola Nacional de saúde Pública Sergio Arouca. Departamento de Epidemiologia e Métodos Quantitativos. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Educação em Saúde e Meio Ambiente. Rio de Janeiro, RJ, Brasil.Universidade Federal do Espírito Santo. Departamento de Nutrição. Vitória, ES, Brasil.Universidade Federal do Espírito Santo. Departamento de Ciências Fisiológicas. Vitória, ES, Brasil.Universidade de São Paulo, São Paulo. Centro de Pesquisa Clínica e Epidemiológica. São Paulo, SP, Brasil.Universidade de São Paulo, São Paulo. Centro de Pesquisa Clínica e Epidemiológica. São Paulo, SP, Brasil.Universidade de São Paulo, São Paulo. Centro de Pesquisa Clínica e Epidemiológica. São Paulo, SP, Brasil.Objective: To evaluate incidence of subclinical and overt hyperthyroidism and hypothyroidism. Subjects and methods: The Brazilian Longitudinal Study of Adult Health (ELSA-Brasil) is a prospective cohort study of 15,105 civil servants, examined at baseline and over a 4-year follow-up. This analysis included 9,705 participants with normal thyroid function at baseline, follow-up information about thyroid function and with no report of using drugs that may interfere in the thyroid function. Thyroid function was defined by TSH/FT4 levels or routine use of thyroid hormones/anti-thyroid medications. Annual and cumulative (over 4-year) incidence rates were presented as percentages (95% Confidence Intervals). Results: The incidence of all overt and subclinical thyroid disease was 6.7% (1.73%/year): 0.19% for overt hyperthyroidism (0.048%/ year), 0.54% for subclinical hyperthyroidism (0.14%/year), 1.98% for overt hypothyroidism (0.51%/year), and 3.99% for subclinical hypothyroidism (1.03%/year). The incidence of all thyroid diseases was higher in women, when compared to men, with a low women:men ratio (1.36). For Blacks the highest incidence was for overt hyperthyroidism, while for Whites, the highest incidence was for overt hypothyroidism. However, the highest incidence of overt hyperthyroidism was detected in Asian descendants. The presence of antithyroperoxidase antibodies at baseline was associated with higher incidence of overt thyroid diseases. Conclusions: These results showed a high incidence of hypothyroidism, which is compatible with a country with a more-than-adequate iodine intake. The low women:men ratio of the incidence of thyroid dysfunction highlights the importance of the diagnosis of thyroid diseases among men in Brazil.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/46989/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALRosaneHGriep_JoseASgarbi_etal_IOC_2021.pdfRosaneHGriep_JoseASgarbi_etal_IOC_2021.pdfapplication/pdf246191https://www.arca.fiocruz.br/bitstream/icict/46989/2/RosaneHGriep_JoseASgarbi_etal_IOC_2021.pdf5b04e573e62c004f2b040d921f575e56MD52TEXTRosaneHGriep_JoseASgarbi_etal_IOC_2021.pdf.txtRosaneHGriep_JoseASgarbi_etal_IOC_2021.pdf.txtExtracted texttext/plain49021https://www.arca.fiocruz.br/bitstream/icict/46989/3/RosaneHGriep_JoseASgarbi_etal_IOC_2021.pdf.txt9aab345efe78fa301704f1c8e36084a0MD53icict/469892021-05-01 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| dc.title.pt_BR.fl_str_mv |
Incidence of thyroid diseases: Results from the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil) |
| title |
Incidence of thyroid diseases: Results from the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil) |
| spellingShingle |
Incidence of thyroid diseases: Results from the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil) Benseñor, Isabela M. Overt thyroid diseases ELSA-Brasil Doenças da tireoide subclínica Hipertiroidismo Hipotireoidismo Incidência Overt thyroid diseases Subclinical thyroid diseases Hyperthyroidism Hypothyroidism Incidence ELSA-Brasil |
| title_short |
Incidence of thyroid diseases: Results from the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil) |
| title_full |
Incidence of thyroid diseases: Results from the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil) |
| title_fullStr |
Incidence of thyroid diseases: Results from the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil) |
| title_full_unstemmed |
Incidence of thyroid diseases: Results from the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil) |
| title_sort |
Incidence of thyroid diseases: Results from the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil) |
| author |
Benseñor, Isabela M. |
| author_facet |
Benseñor, Isabela M. Sgarbi, José Augusto Janovsky, Carolina Castro Porto Silva Pittita, Bianca Almeida Diniz, Maria de Fátima Haueisen Sander Almeida, Maria da Conceição Chagas de Alvim, Sheila Maria Barreto, Sandhi M. Giatti, Luana Duncan, Bruce B. Schmidt, Maria Inês Fonseca, Maria de Jesus M. Griep, Rosane H. Molina, Maria del Carmen B. Mill, João Geraldo Santos, Itamar de Souza Goulart, Alesandra C. Lotudo, Paulo A. |
| author_role |
author |
| author2 |
Sgarbi, José Augusto Janovsky, Carolina Castro Porto Silva Pittita, Bianca Almeida Diniz, Maria de Fátima Haueisen Sander Almeida, Maria da Conceição Chagas de Alvim, Sheila Maria Barreto, Sandhi M. Giatti, Luana Duncan, Bruce B. Schmidt, Maria Inês Fonseca, Maria de Jesus M. Griep, Rosane H. Molina, Maria del Carmen B. Mill, João Geraldo Santos, Itamar de Souza Goulart, Alesandra C. Lotudo, Paulo A. |
| author2_role |
author author author author author author author author author author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Benseñor, Isabela M. Sgarbi, José Augusto Janovsky, Carolina Castro Porto Silva Pittita, Bianca Almeida Diniz, Maria de Fátima Haueisen Sander Almeida, Maria da Conceição Chagas de Alvim, Sheila Maria Barreto, Sandhi M. Giatti, Luana Duncan, Bruce B. Schmidt, Maria Inês Fonseca, Maria de Jesus M. Griep, Rosane H. Molina, Maria del Carmen B. Mill, João Geraldo Santos, Itamar de Souza Goulart, Alesandra C. Lotudo, Paulo A. |
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Overt thyroid diseases ELSA-Brasil Doenças da tireoide subclínica Hipertiroidismo Hipotireoidismo Incidência |
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Overt thyroid diseases ELSA-Brasil Doenças da tireoide subclínica Hipertiroidismo Hipotireoidismo Incidência Overt thyroid diseases Subclinical thyroid diseases Hyperthyroidism Hypothyroidism Incidence ELSA-Brasil |
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Overt thyroid diseases Subclinical thyroid diseases Hyperthyroidism Hypothyroidism Incidence ELSA-Brasil |
| description |
Universidade de São Paulo, São Paulo. Centro de Pesquisa Clínica e Epidemiológica. São Paulo, SP, Brasil. |
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2021 |
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2021-04-30T19:21:39Z |
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2021-04-30T19:21:39Z |
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2021 |
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info:eu-repo/semantics/article |
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BENSEÑOR, Isabela M. et al. Incidence of thyroid diseases: Results from the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil). Arch Endocrinol Metab. Online ahead of print, 11p, 2021. |
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https://www.arca.fiocruz.br/handle/icict/46989 |
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2359-3997 |
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10.20945/2359-3997000000348 |
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2359-4292 |
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BENSEÑOR, Isabela M. et al. Incidence of thyroid diseases: Results from the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil). Arch Endocrinol Metab. Online ahead of print, 11p, 2021. 2359-3997 10.20945/2359-3997000000348 2359-4292 |
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Sociedade Brasileira de Endocrinologia e Metabologia |
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Sociedade Brasileira de Endocrinologia e Metabologia |
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