First report of treatment failure in a patient with cutaneous leishmaniasis infected by Leishmania (Viannia) naiffi carrying Leishmania RNA virus: a fortuitous combination?

Vieira-Gonçalves, Ricardo; Fagundes-Silva, Giselle Aparecida; Heringer, Júlia Furtado; Fantinatti, Maria; Cruz, Alda Maria da; Oliveira-Neto, Manoel Paes; Guerra, Jorge Augusto Oliveira; Gomes-Silva, Adriano

First report of treatment failure in a patient with cutaneous leishmaniasis infected by Leishmania (Viannia) naiffi carrying Leishmania RNA virus: a fortuitous combination?

Detalhes bibliográficos
Autor(a) principal:	Vieira-Gonçalves, Ricardo
Data de Publicação:	2019
Outros Autores:	Fagundes-Silva, Giselle Aparecida, Heringer, Júlia Furtado, Fantinatti, Maria, Cruz, Alda Maria da, Oliveira-Neto, Manoel Paes, Guerra, Jorge Augusto Oliveira, Gomes-Silva, Adriano
Tipo de documento:	Artigo
Idioma:	eng
Título da fonte:	Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo:	https://www.arca.fiocruz.br/handle/icict/33321
Resumo:	Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório Interdisciplinar de Pesquisas Médicas. Rio de Janeiro, RJ, Brasil.

Metadados do item

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spelling	Vieira-Gonçalves, RicardoFagundes-Silva, Giselle AparecidaHeringer, Júlia FurtadoFantinatti, MariaCruz, Alda Maria daOliveira-Neto, Manoel PaesGuerra, Jorge Augusto OliveiraGomes-Silva, Adriano2019-06-03T13:56:15Z2019-06-03T13:56:15Z2019VIEIRA-GONÇALVES, Ricardo et al. First report of treatment failure in a patient with cutaneous leishmaniasis infected by Leishmania (Viannia) naiffi carrying Leishmania RNA virus: a fortuitous combination? Revista da Sociedade Brasileira de Medicina Tropical, v. 52, p. 1-3, 2019.0037-8682https://www.arca.fiocruz.br/handle/icict/3332110.1590/0037-8682-0323-20181678-9849engSociedade Brasileira de Medicina TropicalFirst report of treatment failure in a patient with cutaneous leishmaniasis infected by Leishmania (Viannia) naiffi carrying Leishmania RNA virus: a fortuitous combination?info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório Interdisciplinar de Pesquisas Médicas. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório Interdisciplinar de Pesquisas Médicas. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório Interdisciplinar de Pesquisas Médicas. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório Interdisciplinar de Pesquisas Médicas. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório Interdisciplinar de Pesquisas Médicas. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil.Fundação de Medicina Tropical Dr. Heitor Vieira Dourado. Gerência de Leishmaniose. Manaus, AM, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório Interdisciplinar de Pesquisas Médicas. Rio de Janeiro, RJ, Brasil / Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica em Micobacterioses. Rio de Janeiro, RJ, Brasil.We report the case of a 32-year-old man from Rio de Janeiro, who was infected in the Amazon region of Brazil by Leishmania (Viannia) naiffi. Generally, patients with L. naiffi cutaneous leishmaniasis exhibit a good therapeutic response to either pentavalent antimonials or pentamidine. However, after pentamidine treatment, this patient's infection evolved to therapeutic failure. To understand this clinical outcome, we investigated the presence of the Leishmania RNA virus (LRV) in parasites isolated from the cutaneous lesion; herein, we discuss the possible association between a poor response to pentamidine therapy and the presence of the LRV.Leishmania (Viannia) naiffTherapeutic failureLeishmania RNA virusinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; 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dc.title.pt_BR.fl_str_mv	First report of treatment failure in a patient with cutaneous leishmaniasis infected by Leishmania (Viannia) naiffi carrying Leishmania RNA virus: a fortuitous combination?
title	First report of treatment failure in a patient with cutaneous leishmaniasis infected by Leishmania (Viannia) naiffi carrying Leishmania RNA virus: a fortuitous combination?
spellingShingle	First report of treatment failure in a patient with cutaneous leishmaniasis infected by Leishmania (Viannia) naiffi carrying Leishmania RNA virus: a fortuitous combination? Vieira-Gonçalves, Ricardo Leishmania (Viannia) naiff Therapeutic failure Leishmania RNA virus
title_short	First report of treatment failure in a patient with cutaneous leishmaniasis infected by Leishmania (Viannia) naiffi carrying Leishmania RNA virus: a fortuitous combination?
title_full	First report of treatment failure in a patient with cutaneous leishmaniasis infected by Leishmania (Viannia) naiffi carrying Leishmania RNA virus: a fortuitous combination?
title_fullStr	First report of treatment failure in a patient with cutaneous leishmaniasis infected by Leishmania (Viannia) naiffi carrying Leishmania RNA virus: a fortuitous combination?
title_full_unstemmed	First report of treatment failure in a patient with cutaneous leishmaniasis infected by Leishmania (Viannia) naiffi carrying Leishmania RNA virus: a fortuitous combination?
title_sort	First report of treatment failure in a patient with cutaneous leishmaniasis infected by Leishmania (Viannia) naiffi carrying Leishmania RNA virus: a fortuitous combination?
author	Vieira-Gonçalves, Ricardo
author_facet	Vieira-Gonçalves, Ricardo Fagundes-Silva, Giselle Aparecida Heringer, Júlia Furtado Fantinatti, Maria Cruz, Alda Maria da Oliveira-Neto, Manoel Paes Guerra, Jorge Augusto Oliveira Gomes-Silva, Adriano
author_role	author
author2	Fagundes-Silva, Giselle Aparecida Heringer, Júlia Furtado Fantinatti, Maria Cruz, Alda Maria da Oliveira-Neto, Manoel Paes Guerra, Jorge Augusto Oliveira Gomes-Silva, Adriano
author2_role	author author author author author author author
dc.contributor.author.fl_str_mv	Vieira-Gonçalves, Ricardo Fagundes-Silva, Giselle Aparecida Heringer, Júlia Furtado Fantinatti, Maria Cruz, Alda Maria da Oliveira-Neto, Manoel Paes Guerra, Jorge Augusto Oliveira Gomes-Silva, Adriano
dc.subject.en.pt_BR.fl_str_mv	Leishmania (Viannia) naiff Therapeutic failure Leishmania RNA virus
topic	Leishmania (Viannia) naiff Therapeutic failure Leishmania RNA virus
description	Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório Interdisciplinar de Pesquisas Médicas. Rio de Janeiro, RJ, Brasil.
publishDate	2019
dc.date.accessioned.fl_str_mv	2019-06-03T13:56:15Z
dc.date.available.fl_str_mv	2019-06-03T13:56:15Z
dc.date.issued.fl_str_mv	2019
dc.type.status.fl_str_mv	info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv	info:eu-repo/semantics/article
format	article
status_str	publishedVersion
dc.identifier.citation.fl_str_mv	VIEIRA-GONÇALVES, Ricardo et al. First report of treatment failure in a patient with cutaneous leishmaniasis infected by Leishmania (Viannia) naiffi carrying Leishmania RNA virus: a fortuitous combination? Revista da Sociedade Brasileira de Medicina Tropical, v. 52, p. 1-3, 2019.
dc.identifier.uri.fl_str_mv	https://www.arca.fiocruz.br/handle/icict/33321
dc.identifier.issn.pt_BR.fl_str_mv	0037-8682
dc.identifier.doi.none.fl_str_mv	10.1590/0037-8682-0323-2018
dc.identifier.eissn.none.fl_str_mv	1678-9849
identifier_str_mv	VIEIRA-GONÇALVES, Ricardo et al. First report of treatment failure in a patient with cutaneous leishmaniasis infected by Leishmania (Viannia) naiffi carrying Leishmania RNA virus: a fortuitous combination? Revista da Sociedade Brasileira de Medicina Tropical, v. 52, p. 1-3, 2019. 0037-8682 10.1590/0037-8682-0323-2018 1678-9849
url	https://www.arca.fiocruz.br/handle/icict/33321
dc.language.iso.fl_str_mv	eng
language	eng
dc.rights.driver.fl_str_mv	info:eu-repo/semantics/openAccess
eu_rights_str_mv	openAccess
dc.publisher.none.fl_str_mv	Sociedade Brasileira de Medicina Tropical
publisher.none.fl_str_mv	Sociedade Brasileira de Medicina Tropical
dc.source.none.fl_str_mv	reponame:Repositório Institucional da FIOCRUZ (ARCA) instname:Fundação Oswaldo Cruz (FIOCRUZ) instacron:FIOCRUZ
instname_str	Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str	FIOCRUZ
institution	FIOCRUZ
reponame_str	Repositório Institucional da FIOCRUZ (ARCA)
collection	Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv	https://www.arca.fiocruz.br/bitstream/icict/33321/1/license.txt https://www.arca.fiocruz.br/bitstream/icict/33321/2/ve_Vieira-Gon%c3%a7alves_Ricardo_etal_INI_2019.pdf https://www.arca.fiocruz.br/bitstream/icict/33321/3/ve_Vieira-Gon%c3%a7alves_Ricardo_etal_INI_2019.pdf.txt
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bitstream.checksumAlgorithm.fl_str_mv	MD5 MD5 MD5
repository.name.fl_str_mv	Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)
repository.mail.fl_str_mv	repositorio.arca@fiocruz.br
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First report of treatment failure in a patient with cutaneous leishmaniasis infected by Leishmania (Viannia) naiffi carrying Leishmania RNA virus: a fortuitous combination?

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