Genetic Polymorphism and Molecular Epidemiology of Leishmania (Viannia) braziliensis from Different Hosts and Geographic Areas in Brazil

Detalhes bibliográficos
Autor(a) principal: Cupolillo, Elisa
Data de Publicação: 2003
Outros Autores: Brahim, Lúcia Regina, Toaldo, Cristiane B., Oliveira Neto, Manoel Paes, Brito, Maria Edileuza Felinto de, Falqueto, Aloísio, Naiff, Maricleide de Farias, Grimaldi Jr., Gabriel
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/19329
Resumo: Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisas em Leishmaniose. Rio de Janeiro, RJ, Brasil.
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spelling Cupolillo, ElisaBrahim, Lúcia ReginaToaldo, Cristiane B.Oliveira Neto, Manoel PaesBrito, Maria Edileuza Felinto deFalqueto, AloísioNaiff, Maricleide de FariasGrimaldi Jr., Gabriel2017-06-06T17:20:58Z2017-06-06T17:20:58Z2003CUPOLILLO, Elisa et al. Genetic Polymorphism and Molecular Epidemiology of Leishmania (Viannia) braziliensis from Different Hosts and Geographic Areas in Brazil. Journal of Clinical Microbiology, v. 41, n. 7, p. 3126-3132, July 2003.0095-1137https://www.arca.fiocruz.br/handle/icict/1932910.1128/JCM.41.7.3126-3132.20031098-660XengAmerican Society for MicrobiologyLeishmania braziliensisEpidemiologia MolecularPolimorfismo genéticoBrasilLeishmania (Viannia) braziliensisGenetic PolymorphismMolecular EpidemiologyBrazilGenetic Polymorphism and Molecular Epidemiology of Leishmania (Viannia) braziliensis from Different Hosts and Geographic Areas in Brazilinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisas em Leishmaniose. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisas em Leishmaniose. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisas em Leishmaniose. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Hospital Evandro Chagas. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Centro de Pesquisas Ageu Magalhães. Recife, PE, Brasil.Universidade Federal do Espírito Santo. Vitória, ES, Brasil.Instituto Nacional de Pesquisas da Amazônia. Manaus, AM, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisas em Leishmaniose. Rio de Janeiro, RJ, Brasil.Numerical zymotaxonomy and variability of the internal transcribed spacers (ITS) between the small and large subunits of the rRNA genes were used to examine strain variation and relationships in natural populations of Leishmania (Viannia) braziliensis. A total of 101 strains from distinct hosts and Brazilian geographic regions were assigned to 15 zymodemes clustered in two major genetic groups. The great number of isolates (48.5%) placed in zymodeme IOC/Z-27 were collected on the Atlantic coast. The high molecular diversity found in populations in the Amazon Basin was related to the great number of sandfly vector(s) in that region. The results of the restriction fragment length polymorphism analysis of the ITS depicted considerable intraspecific variation. Genotypic groups A, B, and C contained 39, 40, and 22 isolates, which were divided into 16, 10, and 15 genotypes, respectively. The genetic polymorphism observed demonstrates the degree of diversity of L. (V.) braziliensis strains from different regions where they are endemic. The results reinforce the clonal theory for Leishmania parasites showing the genetic diversity of this pathogen and an association of L. (V.) braziliensis genotypes with specific transmission cycles, probably reflecting an adaptation of different clones to the vector species involved.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/19329/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALgabriel_grimaldijr3_etal_IOC_2003.pdfgabriel_grimaldijr3_etal_IOC_2003.pdfapplication/pdf403024https://www.arca.fiocruz.br/bitstream/icict/19329/2/gabriel_grimaldijr3_etal_IOC_2003.pdfa91c902bdbf366f65e194979c1334edbMD52TEXTgabriel_grimaldijr3_etal_IOC_2003.pdf.txtgabriel_grimaldijr3_etal_IOC_2003.pdf.txtExtracted texttext/plain38738https://www.arca.fiocruz.br/bitstream/icict/19329/3/gabriel_grimaldijr3_etal_IOC_2003.pdf.txt9ed3805d119223d91ace8e4ab274d0abMD53icict/193292022-06-24 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dc.title.pt_BR.fl_str_mv Genetic Polymorphism and Molecular Epidemiology of Leishmania (Viannia) braziliensis from Different Hosts and Geographic Areas in Brazil
title Genetic Polymorphism and Molecular Epidemiology of Leishmania (Viannia) braziliensis from Different Hosts and Geographic Areas in Brazil
spellingShingle Genetic Polymorphism and Molecular Epidemiology of Leishmania (Viannia) braziliensis from Different Hosts and Geographic Areas in Brazil
Cupolillo, Elisa
Leishmania braziliensis
Epidemiologia Molecular
Polimorfismo genético
Brasil
Leishmania (Viannia) braziliensis
Genetic Polymorphism
Molecular Epidemiology
Brazil
title_short Genetic Polymorphism and Molecular Epidemiology of Leishmania (Viannia) braziliensis from Different Hosts and Geographic Areas in Brazil
title_full Genetic Polymorphism and Molecular Epidemiology of Leishmania (Viannia) braziliensis from Different Hosts and Geographic Areas in Brazil
title_fullStr Genetic Polymorphism and Molecular Epidemiology of Leishmania (Viannia) braziliensis from Different Hosts and Geographic Areas in Brazil
title_full_unstemmed Genetic Polymorphism and Molecular Epidemiology of Leishmania (Viannia) braziliensis from Different Hosts and Geographic Areas in Brazil
title_sort Genetic Polymorphism and Molecular Epidemiology of Leishmania (Viannia) braziliensis from Different Hosts and Geographic Areas in Brazil
author Cupolillo, Elisa
author_facet Cupolillo, Elisa
Brahim, Lúcia Regina
Toaldo, Cristiane B.
Oliveira Neto, Manoel Paes
Brito, Maria Edileuza Felinto de
Falqueto, Aloísio
Naiff, Maricleide de Farias
Grimaldi Jr., Gabriel
author_role author
author2 Brahim, Lúcia Regina
Toaldo, Cristiane B.
Oliveira Neto, Manoel Paes
Brito, Maria Edileuza Felinto de
Falqueto, Aloísio
Naiff, Maricleide de Farias
Grimaldi Jr., Gabriel
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Cupolillo, Elisa
Brahim, Lúcia Regina
Toaldo, Cristiane B.
Oliveira Neto, Manoel Paes
Brito, Maria Edileuza Felinto de
Falqueto, Aloísio
Naiff, Maricleide de Farias
Grimaldi Jr., Gabriel
dc.subject.other.pt_BR.fl_str_mv Leishmania braziliensis
Epidemiologia Molecular
Polimorfismo genético
Brasil
topic Leishmania braziliensis
Epidemiologia Molecular
Polimorfismo genético
Brasil
Leishmania (Viannia) braziliensis
Genetic Polymorphism
Molecular Epidemiology
Brazil
dc.subject.en.pt_BR.fl_str_mv Leishmania (Viannia) braziliensis
Genetic Polymorphism
Molecular Epidemiology
Brazil
description Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisas em Leishmaniose. Rio de Janeiro, RJ, Brasil.
publishDate 2003
dc.date.issued.fl_str_mv 2003
dc.date.accessioned.fl_str_mv 2017-06-06T17:20:58Z
dc.date.available.fl_str_mv 2017-06-06T17:20:58Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv CUPOLILLO, Elisa et al. Genetic Polymorphism and Molecular Epidemiology of Leishmania (Viannia) braziliensis from Different Hosts and Geographic Areas in Brazil. Journal of Clinical Microbiology, v. 41, n. 7, p. 3126-3132, July 2003.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/19329
dc.identifier.issn.pt_BR.fl_str_mv 0095-1137
dc.identifier.doi.none.fl_str_mv 10.1128/JCM.41.7.3126-3132.2003
dc.identifier.eissn.none.fl_str_mv 1098-660X
identifier_str_mv CUPOLILLO, Elisa et al. Genetic Polymorphism and Molecular Epidemiology of Leishmania (Viannia) braziliensis from Different Hosts and Geographic Areas in Brazil. Journal of Clinical Microbiology, v. 41, n. 7, p. 3126-3132, July 2003.
0095-1137
10.1128/JCM.41.7.3126-3132.2003
1098-660X
url https://www.arca.fiocruz.br/handle/icict/19329
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv American Society for Microbiology
publisher.none.fl_str_mv American Society for Microbiology
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
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https://www.arca.fiocruz.br/bitstream/icict/19329/3/gabriel_grimaldijr3_etal_IOC_2003.pdf.txt
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