Human Mesenchymal Stem Cell Therapy Reverses SU5416/Hypoxia-Induced Pulmonary Arterial Hypertension in Mice
Autor(a) principal: | |
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Data de Publicação: | 2018 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
Texto Completo: | https://www.arca.fiocruz.br/handle/icict/31472 |
Resumo: | AUTHORS - Allan K. N. Alencar1, Pedro M. Pimentel-Coelho2, Guilherme C. Montes1, Marina de M. C. da Silva1, Luiza V. P. Mendes1, Tadeu L. Montagnoli1, Ananssa M. S. Silva1, Juliana Ferreira Vasques2, Paulo Henrique Rosado-de-Castro3, Bianca Gutfilen4, Valéria do M. N. Cunha1, Aline G. M. Fraga5, Patrícia M R e Silva6, Marco Aurélio Martins6, Tatiana Paula Teixeira Ferreira6, Rosalia Mendes-Otero2, Margarete M. Trachez1, Roberto T. Sudo1 and Gisele Zapata-Sudo1* -- AFFILIATIONS - 1Programa de Pesquisa em Desenvolvimento de Fármacos, Instituto de Ciências Biomédicas, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil 2Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil 3Instituto de Ciências Biomédicas, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil 4Faculdade de Medicina, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil 5Faculdade de Farmácia, Universidade Federal do Rio de Janeiro, Centro de Ciências da Saúde, Rio de Janeiro, Brazil 6Instituto Oswaldo Cruz/FIOCRUZ, Rio de Janeiro, Brazil. |
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Silva, Patrícia M. R. eMartins, Marco AurélioFerreira, Tatiana Paula TeixeiraMúltipla autoria - ver em Notas2019-02-07T12:37:25Z2019-02-07T12:37:25Z2018ALENCAR, Allan K. N. et al. Human Mesenchymal Stem Cell Therapy reverses Su5416/Hypoxia-Induced Pulmonary Arterial Hypertension in Mice. Frontiers in Pharmacology, v.9, Article 1395, 16p, Dec. 2018.1663-9812https://www.arca.fiocruz.br/handle/icict/31472AUTHORS - Allan K. N. Alencar1, Pedro M. Pimentel-Coelho2, Guilherme C. Montes1, Marina de M. C. da Silva1, Luiza V. P. Mendes1, Tadeu L. Montagnoli1, Ananssa M. S. Silva1, Juliana Ferreira Vasques2, Paulo Henrique Rosado-de-Castro3, Bianca Gutfilen4, Valéria do M. N. Cunha1, Aline G. M. Fraga5, Patrícia M R e Silva6, Marco Aurélio Martins6, Tatiana Paula Teixeira Ferreira6, Rosalia Mendes-Otero2, Margarete M. Trachez1, Roberto T. Sudo1 and Gisele Zapata-Sudo1* -- AFFILIATIONS - 1Programa de Pesquisa em Desenvolvimento de Fármacos, Instituto de Ciências Biomédicas, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil 2Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil 3Instituto de Ciências Biomédicas, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil 4Faculdade de Medicina, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil 5Faculdade de Farmácia, Universidade Federal do Rio de Janeiro, Centro de Ciências da Saúde, Rio de Janeiro, Brazil 6Instituto Oswaldo Cruz/FIOCRUZ, Rio de Janeiro, Brazil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil.Múltipla autoria - ver em NotasAims:Pulmonaryarterialhypertension(PAH)isadiseasecharacterizedbyanincreasein pulmonary vascular resistance and right ventricular (RV) failure. We aimed to determine theeffectsofhumanmesenchymalstemcell(hMSC)therapyinaSU5416/hypoxia(SuH) mice model of PAH.engFrontiers MediaHipertensão arterial pulmonarProliferação celularInflamaçãoApoptoseCélulas-tronco mesenquimais humanasPulmonary arterial hypertensionCell proliferationInflammationApoptosisHuman mesenchymal stem cellHuman Mesenchymal Stem Cell Therapy Reverses SU5416/Hypoxia-Induced Pulmonary Arterial Hypertension in Miceinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; 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dc.title.pt_BR.fl_str_mv |
Human Mesenchymal Stem Cell Therapy Reverses SU5416/Hypoxia-Induced Pulmonary Arterial Hypertension in Mice |
title |
Human Mesenchymal Stem Cell Therapy Reverses SU5416/Hypoxia-Induced Pulmonary Arterial Hypertension in Mice |
spellingShingle |
Human Mesenchymal Stem Cell Therapy Reverses SU5416/Hypoxia-Induced Pulmonary Arterial Hypertension in Mice Silva, Patrícia M. R. e Hipertensão arterial pulmonar Proliferação celular Inflamação Apoptose Células-tronco mesenquimais humanas Pulmonary arterial hypertension Cell proliferation Inflammation Apoptosis Human mesenchymal stem cell |
title_short |
Human Mesenchymal Stem Cell Therapy Reverses SU5416/Hypoxia-Induced Pulmonary Arterial Hypertension in Mice |
title_full |
Human Mesenchymal Stem Cell Therapy Reverses SU5416/Hypoxia-Induced Pulmonary Arterial Hypertension in Mice |
title_fullStr |
Human Mesenchymal Stem Cell Therapy Reverses SU5416/Hypoxia-Induced Pulmonary Arterial Hypertension in Mice |
title_full_unstemmed |
Human Mesenchymal Stem Cell Therapy Reverses SU5416/Hypoxia-Induced Pulmonary Arterial Hypertension in Mice |
title_sort |
Human Mesenchymal Stem Cell Therapy Reverses SU5416/Hypoxia-Induced Pulmonary Arterial Hypertension in Mice |
author |
Silva, Patrícia M. R. e |
author_facet |
Silva, Patrícia M. R. e Martins, Marco Aurélio Ferreira, Tatiana Paula Teixeira Múltipla autoria - ver em Notas |
author_role |
author |
author2 |
Martins, Marco Aurélio Ferreira, Tatiana Paula Teixeira Múltipla autoria - ver em Notas |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Silva, Patrícia M. R. e Martins, Marco Aurélio Ferreira, Tatiana Paula Teixeira Múltipla autoria - ver em Notas |
dc.subject.other.pt_BR.fl_str_mv |
Hipertensão arterial pulmonar Proliferação celular Inflamação Apoptose Células-tronco mesenquimais humanas |
topic |
Hipertensão arterial pulmonar Proliferação celular Inflamação Apoptose Células-tronco mesenquimais humanas Pulmonary arterial hypertension Cell proliferation Inflammation Apoptosis Human mesenchymal stem cell |
dc.subject.en.pt_BR.fl_str_mv |
Pulmonary arterial hypertension Cell proliferation Inflammation Apoptosis Human mesenchymal stem cell |
description |
AUTHORS - Allan K. N. Alencar1, Pedro M. Pimentel-Coelho2, Guilherme C. Montes1, Marina de M. C. da Silva1, Luiza V. P. Mendes1, Tadeu L. Montagnoli1, Ananssa M. S. Silva1, Juliana Ferreira Vasques2, Paulo Henrique Rosado-de-Castro3, Bianca Gutfilen4, Valéria do M. N. Cunha1, Aline G. M. Fraga5, Patrícia M R e Silva6, Marco Aurélio Martins6, Tatiana Paula Teixeira Ferreira6, Rosalia Mendes-Otero2, Margarete M. Trachez1, Roberto T. Sudo1 and Gisele Zapata-Sudo1* -- AFFILIATIONS - 1Programa de Pesquisa em Desenvolvimento de Fármacos, Instituto de Ciências Biomédicas, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil 2Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil 3Instituto de Ciências Biomédicas, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil 4Faculdade de Medicina, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil 5Faculdade de Farmácia, Universidade Federal do Rio de Janeiro, Centro de Ciências da Saúde, Rio de Janeiro, Brazil 6Instituto Oswaldo Cruz/FIOCRUZ, Rio de Janeiro, Brazil. |
publishDate |
2018 |
dc.date.issued.fl_str_mv |
2018 |
dc.date.accessioned.fl_str_mv |
2019-02-07T12:37:25Z |
dc.date.available.fl_str_mv |
2019-02-07T12:37:25Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
ALENCAR, Allan K. N. et al. Human Mesenchymal Stem Cell Therapy reverses Su5416/Hypoxia-Induced Pulmonary Arterial Hypertension in Mice. Frontiers in Pharmacology, v.9, Article 1395, 16p, Dec. 2018. |
dc.identifier.uri.fl_str_mv |
https://www.arca.fiocruz.br/handle/icict/31472 |
dc.identifier.issn.pt_BR.fl_str_mv |
1663-9812 |
identifier_str_mv |
ALENCAR, Allan K. N. et al. Human Mesenchymal Stem Cell Therapy reverses Su5416/Hypoxia-Induced Pulmonary Arterial Hypertension in Mice. Frontiers in Pharmacology, v.9, Article 1395, 16p, Dec. 2018. 1663-9812 |
url |
https://www.arca.fiocruz.br/handle/icict/31472 |
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eng |
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eng |
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info:eu-repo/semantics/openAccess |
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Frontiers Media |
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Frontiers Media |
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