Imported and intensive care unit-born Acinetobacter baumannii clonal complexes: one-year prospective cohort study in intensive care patients

Detalhes bibliográficos
Autor(a) principal: Martins, Natacha
Data de Publicação: 2013
Outros Autores: Martins, Ianick Souto, Freitas, Wania Vasconcelos de, Matos, Juliana Arruda de, Girão, Valeria Brígido de Carvalho, Coelho-Souza, Talita, Maralhães, Ana Cristina de Gouveia, Cacci, Luciana Camila, Figueiredo, Miriam Perez de, Dias, Rubens Clayton Silva, Costa-Lourenço, Ana Paula Ramalho, Ferreira, Adriana Lúcia Pires, Dalla-Costa, Libera, Nouér, Simone Aranha, Santoro-Lopes, Guillherme, Riley, Lee W., Moreira, Beatriz Meurer
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/36168
Resumo: Juliana Arruda de Matos. Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Documento produzido em parceria ou por autor vinculado à Fiocruz, mas não consta a informação no documento.
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spelling Martins, NatachaMartins, Ianick SoutoFreitas, Wania Vasconcelos deMatos, Juliana Arruda deGirão, Valeria Brígido de CarvalhoCoelho-Souza, TalitaMaralhães, Ana Cristina de GouveiaCacci, Luciana CamilaFigueiredo, Miriam Perez deDias, Rubens Clayton SilvaCosta-Lourenço, Ana Paula RamalhoFerreira, Adriana Lúcia PiresDalla-Costa, LiberaNouér, Simone AranhaSantoro-Lopes, GuillhermeRiley, Lee W.Moreira, Beatriz Meurer2019-10-04T14:12:47Z2019-10-04T14:12:47Z2013MARTINS, Natacha et al. Imported and intensive care unit-born Acinetobacter baumannii clonal complexes: one-year prospective cohort study in intensive care patients. Microbial Drug Resistance, p. 1-18, 2013.1076-6294https://www.arca.fiocruz.br/handle/icict/3616810.1089/mdr.2012.01741931-8448Juliana Arruda de Matos. Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Documento produzido em parceria ou por autor vinculado à Fiocruz, mas não consta a informação no documento.2020-10-04Federal University of Rio de Janeiro. Institute of Microbiology. Rio de Janeiro, RJ, Brazil.Fluminense Federal University. School of Medicine. Niterói, RJ, Brazil.Federal University of Rio de Janeiro. School of Medicine. Rio de Janeiro, RJ, Brazil.Federal University of Rio de Janeiro. School of Medicine. Rio de Janeiro, RJ, Brazil.Federal University of Rio de Janeiro. Institute of Microbiology. Rio de Janeiro, RJ, Brazil.Federal University of Rio de Janeiro. Institute of Microbiology. Rio de Janeiro, RJ, Brazil.Federal University of Rio de Janeiro. School of Medicine. Rio de Janeiro, RJ, Brazil.Federal University of Rio de Janeiro. School of Medicine. Rio de Janeiro, RJ, Brazil.Federal University of Rio de Janeiro. School of Medicine. Rio de Janeiro, RJ, Brazil.Federal University of the State of Rio de Janeiro. Microbiology and Parasitology Department. Rio de Janeiro, RJ, Brazil.Federal University of Rio de Janeiro. Institute of Microbiology. Rio de Janeiro, RJ, Brazil.Federal University of Rio de Janeiro. School of Medicine. Rio de Janeiro, RJ, Brazil.Federal University of Paraná. Clinical Hospital. Curitiba, PR, Brazil / Research Institute Little Prince Pelé. Little Prince School. Curitiba, PR, Brazil.Federal University of Rio de Janeiro. School of Medicine. Rio de Janeiro, RJ, Brazil.Federal University of Rio de Janeiro. School of Medicine. Rio de Janeiro, RJ, Brazil.University of California. School of Public Health. Berkeley, CA, USA..Federal University of Rio de Janeiro. Institute of Microbiology. Rio de Janeiro, RJ, Brazil.The main objective of this study was to assess the frequency and possible sources of colonization and infection by Acinetobacter in the intensive care unit (ICU) of a university hospital in Rio de Janeiro, Brazil, and characterize the isolates for relatedness to internationally and locally disseminated lineages. Patients consecutively admitted to the ICU from April 2007 to April 2008 were screened for colonization and infection. Species were identified by rpoB sequencing. The presence of acquired and intrinsic carbapenemase genes was assessed by polymerase chain reaction (PCR). Strains were typed by random amplification of polymorphic DNA (RAPD)-PCR, pulsed-field gel electrophoresis, and multilocus sequence typing (MLST) using the schemes hosted at the University of Oxford (UO) and Institut Pasteur (IP). Of 234 patients, 98 (42%) had at least one specimen positive for the Acinetobacter isolate, and 24 (10%) had infection. A total of 22 (92%) infections were caused by Acinetobacter baumannii and one each (4%) by Acinetobacter nosocomialis and Acinetobacter berezinae. A. baumannii isolates from 60 patients belonged to RAPD types that corresponded to MLST clonal complexes (CCs) 109/1 (UO/IP scheme, known as International Clone I), CC 110/110 (UO/IP), CC 113/79 (UO/IP), and CC 104/15 (UO/IP). Most CCs were carbapenem resistant and carried the blaOXA-23-like gene. Strains were introduced by patients transferred from other wards of the same hospital (11 patients, 18%) or acquired from cross-transmission within the ICU (49 patients, 82%). A. nosocomialis lineage sequence type 260 colonized 10% of the whole study population. A. baumannii have become established in this hospital as a part of a global epidemic of successful clones. Once introduced into the hospital, such clones have become entrenched among patients in the ICU.engMary Ann LieberImported and intensive care unit-born Acinetobacter baumannii clonal complexes: one-year prospective cohort study in intensive care patientsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleAcinetobacter baumanniiICUIntensive care patientsinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txttext/plain1748https://www.arca.fiocruz.br/bitstream/icict/36168/1/license.txt8a4605be74aa9ea9d79846c1fba20a33MD51ORIGINALve_Martins_Natacha_etal_INI_2013.pdfve_Martins_Natacha_etal_INI_2013.pdfapplication/pdf424564https://www.arca.fiocruz.br/bitstream/icict/36168/2/ve_Martins_Natacha_etal_INI_2013.pdf8c3a532df0b538a8ff4c25951dc9f0baMD52TEXTve_Martins_Natacha_etal_INI_2013.pdf.txtve_Martins_Natacha_etal_INI_2013.pdf.txtExtracted texttext/plain36830https://www.arca.fiocruz.br/bitstream/icict/36168/3/ve_Martins_Natacha_etal_INI_2013.pdf.txtf6ae67b32cc4c3b612eeff7dca7aa25eMD53icict/361682021-03-24 16:32:37.308oai:www.arca.fiocruz.br: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Repositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352021-03-24T19:32:37Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv Imported and intensive care unit-born Acinetobacter baumannii clonal complexes: one-year prospective cohort study in intensive care patients
title Imported and intensive care unit-born Acinetobacter baumannii clonal complexes: one-year prospective cohort study in intensive care patients
spellingShingle Imported and intensive care unit-born Acinetobacter baumannii clonal complexes: one-year prospective cohort study in intensive care patients
Martins, Natacha
Acinetobacter baumannii
ICU
Intensive care patients
title_short Imported and intensive care unit-born Acinetobacter baumannii clonal complexes: one-year prospective cohort study in intensive care patients
title_full Imported and intensive care unit-born Acinetobacter baumannii clonal complexes: one-year prospective cohort study in intensive care patients
title_fullStr Imported and intensive care unit-born Acinetobacter baumannii clonal complexes: one-year prospective cohort study in intensive care patients
title_full_unstemmed Imported and intensive care unit-born Acinetobacter baumannii clonal complexes: one-year prospective cohort study in intensive care patients
title_sort Imported and intensive care unit-born Acinetobacter baumannii clonal complexes: one-year prospective cohort study in intensive care patients
author Martins, Natacha
author_facet Martins, Natacha
Martins, Ianick Souto
Freitas, Wania Vasconcelos de
Matos, Juliana Arruda de
Girão, Valeria Brígido de Carvalho
Coelho-Souza, Talita
Maralhães, Ana Cristina de Gouveia
Cacci, Luciana Camila
Figueiredo, Miriam Perez de
Dias, Rubens Clayton Silva
Costa-Lourenço, Ana Paula Ramalho
Ferreira, Adriana Lúcia Pires
Dalla-Costa, Libera
Nouér, Simone Aranha
Santoro-Lopes, Guillherme
Riley, Lee W.
Moreira, Beatriz Meurer
author_role author
author2 Martins, Ianick Souto
Freitas, Wania Vasconcelos de
Matos, Juliana Arruda de
Girão, Valeria Brígido de Carvalho
Coelho-Souza, Talita
Maralhães, Ana Cristina de Gouveia
Cacci, Luciana Camila
Figueiredo, Miriam Perez de
Dias, Rubens Clayton Silva
Costa-Lourenço, Ana Paula Ramalho
Ferreira, Adriana Lúcia Pires
Dalla-Costa, Libera
Nouér, Simone Aranha
Santoro-Lopes, Guillherme
Riley, Lee W.
Moreira, Beatriz Meurer
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Martins, Natacha
Martins, Ianick Souto
Freitas, Wania Vasconcelos de
Matos, Juliana Arruda de
Girão, Valeria Brígido de Carvalho
Coelho-Souza, Talita
Maralhães, Ana Cristina de Gouveia
Cacci, Luciana Camila
Figueiredo, Miriam Perez de
Dias, Rubens Clayton Silva
Costa-Lourenço, Ana Paula Ramalho
Ferreira, Adriana Lúcia Pires
Dalla-Costa, Libera
Nouér, Simone Aranha
Santoro-Lopes, Guillherme
Riley, Lee W.
Moreira, Beatriz Meurer
dc.subject.en.pt_BR.fl_str_mv Acinetobacter baumannii
ICU
Intensive care patients
topic Acinetobacter baumannii
ICU
Intensive care patients
description Juliana Arruda de Matos. Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Documento produzido em parceria ou por autor vinculado à Fiocruz, mas não consta a informação no documento.
publishDate 2013
dc.date.issued.fl_str_mv 2013
dc.date.accessioned.fl_str_mv 2019-10-04T14:12:47Z
dc.date.available.fl_str_mv 2019-10-04T14:12:47Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv MARTINS, Natacha et al. Imported and intensive care unit-born Acinetobacter baumannii clonal complexes: one-year prospective cohort study in intensive care patients. Microbial Drug Resistance, p. 1-18, 2013.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/36168
dc.identifier.issn.pt_BR.fl_str_mv 1076-6294
dc.identifier.doi.none.fl_str_mv 10.1089/mdr.2012.0174
dc.identifier.eissn.none.fl_str_mv 1931-8448
identifier_str_mv MARTINS, Natacha et al. Imported and intensive care unit-born Acinetobacter baumannii clonal complexes: one-year prospective cohort study in intensive care patients. Microbial Drug Resistance, p. 1-18, 2013.
1076-6294
10.1089/mdr.2012.0174
1931-8448
url https://www.arca.fiocruz.br/handle/icict/36168
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Mary Ann Lieber
publisher.none.fl_str_mv Mary Ann Lieber
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
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