Association Between Mast Cells and Collagen Maturation in Chronic Periodontitis in Humans

Detalhes bibliográficos
Autor(a) principal: Ribeiro, Lívia Silva Figueiredo e
Data de Publicação: 2018
Outros Autores: Santos, Jean Nunes dos, Rocha, Clarissa Araújo Gurgel, Cury, Patricia Ramos
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/28204
Resumo: Rocha, Clarissa Araújo Gurgel. “Documento produzido em parceria ou por autor vinculado à Fiocruz, mas não consta à informação no documento”.
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spelling Ribeiro, Lívia Silva Figueiredo eSantos, Jean Nunes dosRocha, Clarissa Araújo GurgelCury, Patricia Ramos2018-08-17T12:22:47Z2018-08-17T12:22:47Z2018RIBEIRO, L. S. F. et al. Association Between Mast Cells and Collagen Maturation in Chronic Periodontitis in Humans. Journal of Histochemistry & Cytochemistry, v. 66, n. 6, p. 467–475, 2018.0022-1554https://www.arca.fiocruz.br/handle/icict/2820410.1369/0022155418765131Rocha, Clarissa Araújo Gurgel. “Documento produzido em parceria ou por autor vinculado à Fiocruz, mas não consta à informação no documento”.National Council for Scientific and Technological Development (303003/2015-4).Federal University of Bahia. Department of Oral Pathology. Postgraduate Program in Health and Dentistry. Salvador, BA, Brazil / Federal University of Bahia. School of Dentistry. Department of Periodontics. Salvador, BA, BrazilFederal University of Bahia. Department of Oral Pathology. Postgraduate Program in Health and Dentistry. Salvador, BA, Brazil / Federal University of Bahia. School of Dentistry. Department of Periodontics. Salvador, BA, BrazilFederal University of Bahia. Department of Oral Pathology. Postgraduate Program in Health and Dentistry. Salvador, BA, Brazil / Federal University of Bahia. School of Dentistry. Department of Periodontics. Salvador, BA, BrazilFederal University of Bahia. Department of Oral Pathology. Postgraduate Program in Health and Dentistry. Salvador, BA, Brazil / Federal University of Bahia. School of Dentistry. Department of Periodontics. Salvador, BA, BrazilMast cells (MCs) can influence the maturation of collagen fibers. This study evaluated the relationship between the distribution and degranulation of MCs and collagen maturation in human gingival tissue in chronic periodontitis. A total of 16 specimens of patients clinically diagnosed as periodontitis and 18 controls clinically diagnosed as healthy or gingivitis were included. Immunohistochemistry and Picrosirius staining were performed to identify MCs and assess collagen fibers, respectively. Chi-square, t test, and Pearson's correlation test ( p<0.05) were used. In control specimens, there was a positive association between MCs in the connective tissue and the presence of immature collagen ( p=0.001); in periodontitis samples, this association was not confirmed ( p≥0.12). There was no significant relationship between periodontal diagnosis and collagen maturation or MC degranulation ( p≥0.35). MC density was significantly higher ( p=0.04) in periodontitis tissue (339.01 ± 188.94 MCs/mm2) than in control tissue (211.14 ± 131.13 MCs/mm2) in the area of connective tissue containing inflammatory infiltrate. There was a correlation between the number of MCs and probing depth ( r = 0.34, p=0.04). MCs are involved in the pathogenesis of periodontal diseases and might be associated with collagen maturation in periodontal tissue during the early stages of periodontal disease pathogenesis.engSAGE PublicationsColágenoHumanoInflamaçãoMastócitosPeriodontiteCollagenHumanInflammationMast cellsPeriodontitisAssociation Between Mast Cells and Collagen Maturation in Chronic Periodontitis in Humansinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/28204/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALRibeiro LS Association Between Mast Cells and Collagen....pdfRibeiro LS Association Between Mast Cells and 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dc.title.pt_BR.fl_str_mv Association Between Mast Cells and Collagen Maturation in Chronic Periodontitis in Humans
title Association Between Mast Cells and Collagen Maturation in Chronic Periodontitis in Humans
spellingShingle Association Between Mast Cells and Collagen Maturation in Chronic Periodontitis in Humans
Ribeiro, Lívia Silva Figueiredo e
Colágeno
Humano
Inflamação
Mastócitos
Periodontite
Collagen
Human
Inflammation
Mast cells
Periodontitis
title_short Association Between Mast Cells and Collagen Maturation in Chronic Periodontitis in Humans
title_full Association Between Mast Cells and Collagen Maturation in Chronic Periodontitis in Humans
title_fullStr Association Between Mast Cells and Collagen Maturation in Chronic Periodontitis in Humans
title_full_unstemmed Association Between Mast Cells and Collagen Maturation in Chronic Periodontitis in Humans
title_sort Association Between Mast Cells and Collagen Maturation in Chronic Periodontitis in Humans
author Ribeiro, Lívia Silva Figueiredo e
author_facet Ribeiro, Lívia Silva Figueiredo e
Santos, Jean Nunes dos
Rocha, Clarissa Araújo Gurgel
Cury, Patricia Ramos
author_role author
author2 Santos, Jean Nunes dos
Rocha, Clarissa Araújo Gurgel
Cury, Patricia Ramos
author2_role author
author
author
dc.contributor.author.fl_str_mv Ribeiro, Lívia Silva Figueiredo e
Santos, Jean Nunes dos
Rocha, Clarissa Araújo Gurgel
Cury, Patricia Ramos
dc.subject.other.pt_BR.fl_str_mv Colágeno
Humano
Inflamação
Mastócitos
Periodontite
topic Colágeno
Humano
Inflamação
Mastócitos
Periodontite
Collagen
Human
Inflammation
Mast cells
Periodontitis
dc.subject.en.pt_BR.fl_str_mv Collagen
Human
Inflammation
Mast cells
Periodontitis
description Rocha, Clarissa Araújo Gurgel. “Documento produzido em parceria ou por autor vinculado à Fiocruz, mas não consta à informação no documento”.
publishDate 2018
dc.date.accessioned.fl_str_mv 2018-08-17T12:22:47Z
dc.date.available.fl_str_mv 2018-08-17T12:22:47Z
dc.date.issued.fl_str_mv 2018
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv RIBEIRO, L. S. F. et al. Association Between Mast Cells and Collagen Maturation in Chronic Periodontitis in Humans. Journal of Histochemistry & Cytochemistry, v. 66, n. 6, p. 467–475, 2018.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/28204
dc.identifier.issn.pt_BR.fl_str_mv 0022-1554
dc.identifier.doi.none.fl_str_mv 10.1369/0022155418765131
identifier_str_mv RIBEIRO, L. S. F. et al. Association Between Mast Cells and Collagen Maturation in Chronic Periodontitis in Humans. Journal of Histochemistry & Cytochemistry, v. 66, n. 6, p. 467–475, 2018.
0022-1554
10.1369/0022155418765131
url https://www.arca.fiocruz.br/handle/icict/28204
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv SAGE Publications
publisher.none.fl_str_mv SAGE Publications
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
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