Hepatitis delta: virological and clinical aspects

Detalhes bibliográficos
Autor(a) principal: Vieira, Deusilene Souza
Data de Publicação: 2017
Outros Autores: Souza, Luan Felipo Botelho, Vasconcelos, Mariana Pinheiro Alves, Santos, Alcione de Oliveira dos, Salcedo, Juan Miguel Villalobos
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/27014
Resumo: Fundação Oswaldo Cruz. Laboratório de Virologia Molecular. Porto Velho, RO, Brasil / Fundação Oswaldo Cruz. Centro de Pesquisa em Medicina Tropical. Ambulatório de Hepatites Virais. Porto Velho, RO, Brasil / Programa de Pós-Graduação em Biologia Experimental. Porto Velho, RO, Brasil.
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spelling Vieira, Deusilene SouzaSouza, Luan Felipo BotelhoVasconcelos, Mariana Pinheiro AlvesSantos, Alcione de Oliveira dosSalcedo, Juan Miguel Villalobos2018-06-20T14:27:28Z2018-06-20T14:27:28Z2017VIEIRA, D. S. et al. Hepatitis delta: virological and clinical aspects. Virology Journal, p. 1-15. 2017.https://www.arca.fiocruz.br/handle/icict/2701410.1186/s12985-017-0845-yengBioMed CentralHepatitis delta: virological and clinical aspectsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Laboratório de Virologia Molecular. Porto Velho, RO, Brasil / Fundação Oswaldo Cruz. Centro de Pesquisa em Medicina Tropical. Ambulatório de Hepatites Virais. Porto Velho, RO, Brasil / Programa de Pós-Graduação em Biologia Experimental. Porto Velho, RO, Brasil.Fundação Oswaldo Cruz. Laboratório de Virologia Molecular. Porto Velho, RO, Brasil / Fundação Oswaldo Cruz. Centro de Pesquisa em Medicina Tropical. Ambulatório de Hepatites Virais. Porto Velho, RO, Brasil / Programa de Pós-Graduação em Biologia Experimental. Porto Velho, RO, Brasil.Instituto de Infectologia Emílio Ribas. São Paulo, SP, Brasil.Fundação Oswaldo Cruz. Laboratório de Virologia Molecular. Porto Velho, RO, Brasil / Fundação Oswaldo Cruz. Centro de Pesquisa em Medicina Tropical. Ambulatório de Hepatites Virais. Porto Velho, RO, Brasil / Programa de Pós-Graduação em Biologia Experimental. Porto Velho, RO, Brasil.Fundação Oswaldo Cruz. Laboratório de Virologia Molecular. Porto Velho, RO, Brasil / Fundação Oswaldo Cruz. Centro de Pesquisa em Medicina Tropical. Ambulatório de Hepatites Virais. Porto Velho, RO, Brasil / Programa de Pós-Graduação em Biologia Experimental. Porto Velho, RO, Brasil.There are an estimated 400 million chronic carriers of HBV worldwide; between 15 and 20 million have serological evidence of exposure to HDV. Traditionally, regions with high rates of endemicity are central and northern Africa, the Amazon Basin, eastern Europe and the Mediterranean, the Middle East and parts of Asia. There are two types of HDV/HBV infection which are differentiated by the previous status infection by HBV for the individual. Individuals with acute HBV infection contaminated by HDV is an HDV/HBV co-infection, while individuals with chronic HBV infection contaminated by HDV represent an HDV/HBV super-infection. The appropriate treatment for chronic hepatitis delta is still widely discussed since it does not have an effective drug. Alpha interferon is currently the only licensed therapy for the treatment of chronic hepatitis D. The most widely used drug is pegylated interferon but only approximately 25% of patients maintain a sustained viral response after 1 year of treatment. The best marker of therapeutic success would be the clearance of HBsAg, but this data is rare in clinical practice. Therefore, the best way to predict a sustained virologic response is the maintenance of undetectable HDV RNA levels.HDVVirologyClinical aspectsinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-83067https://www.arca.fiocruz.br/bitstream/icict/27014/1/license.txt2fa08f22073209e2961a7c9c27e5386eMD51ORIGINALHDV revisão.pdfHDV revisão.pdfapplication/pdf1300647https://www.arca.fiocruz.br/bitstream/icict/27014/2/HDV%20revis%c3%a3o.pdf29ce7b254f0b5edebec8a109fbf7abcfMD52TEXTHDV revisão.pdf.txtHDV revisão.pdf.txtExtracted texttext/plain84816https://www.arca.fiocruz.br/bitstream/icict/27014/3/HDV%20revis%c3%a3o.pdf.txtb1bc47df01ada485703a1826f7db8efcMD53icict/270142018-10-17 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dc.title.pt_BR.fl_str_mv Hepatitis delta: virological and clinical aspects
title Hepatitis delta: virological and clinical aspects
spellingShingle Hepatitis delta: virological and clinical aspects
Vieira, Deusilene Souza
HDV
Virology
Clinical aspects
title_short Hepatitis delta: virological and clinical aspects
title_full Hepatitis delta: virological and clinical aspects
title_fullStr Hepatitis delta: virological and clinical aspects
title_full_unstemmed Hepatitis delta: virological and clinical aspects
title_sort Hepatitis delta: virological and clinical aspects
author Vieira, Deusilene Souza
author_facet Vieira, Deusilene Souza
Souza, Luan Felipo Botelho
Vasconcelos, Mariana Pinheiro Alves
Santos, Alcione de Oliveira dos
Salcedo, Juan Miguel Villalobos
author_role author
author2 Souza, Luan Felipo Botelho
Vasconcelos, Mariana Pinheiro Alves
Santos, Alcione de Oliveira dos
Salcedo, Juan Miguel Villalobos
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Vieira, Deusilene Souza
Souza, Luan Felipo Botelho
Vasconcelos, Mariana Pinheiro Alves
Santos, Alcione de Oliveira dos
Salcedo, Juan Miguel Villalobos
dc.subject.en.pt_BR.fl_str_mv HDV
Virology
Clinical aspects
topic HDV
Virology
Clinical aspects
description Fundação Oswaldo Cruz. Laboratório de Virologia Molecular. Porto Velho, RO, Brasil / Fundação Oswaldo Cruz. Centro de Pesquisa em Medicina Tropical. Ambulatório de Hepatites Virais. Porto Velho, RO, Brasil / Programa de Pós-Graduação em Biologia Experimental. Porto Velho, RO, Brasil.
publishDate 2017
dc.date.issued.fl_str_mv 2017
dc.date.accessioned.fl_str_mv 2018-06-20T14:27:28Z
dc.date.available.fl_str_mv 2018-06-20T14:27:28Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv VIEIRA, D. S. et al. Hepatitis delta: virological and clinical aspects. Virology Journal, p. 1-15. 2017.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/27014
dc.identifier.doi.pt_BR.fl_str_mv 10.1186/s12985-017-0845-y
identifier_str_mv VIEIRA, D. S. et al. Hepatitis delta: virological and clinical aspects. Virology Journal, p. 1-15. 2017.
10.1186/s12985-017-0845-y
url https://www.arca.fiocruz.br/handle/icict/27014
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv BioMed Central
publisher.none.fl_str_mv BioMed Central
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
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