Effect of stearic acid on the mechanical and rheological properties of PLA/ HA biocomposites

Detalhes bibliográficos
Autor(a) principal: Andrade, Júlia Cé de
Data de Publicação: 2023
Outros Autores: Cabral, Fernando, Clemens, Frank Jorg, Vieira, Jaqueline Leite, Soares, Milena B. P., Hotza, Dachamir, Fredel, Márcio Celso
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/60889
Resumo: Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq). Fundação Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES).
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spelling Andrade, Júlia Cé deCabral, FernandoClemens, Frank JorgVieira, Jaqueline LeiteSoares, Milena B. P.Hotza, DachamirFredel, Márcio Celso2023-10-24T13:57:55Z2023-10-24T13:57:55Z2023ANDRADE, Júlia Cé de et al. Effect of stearic acid on the mechanical and rheological properties of PLA/ HA biocomposites. Materials Today Communications, v. 35, p. 1-7, 2023.2352-4928https://www.arca.fiocruz.br/handle/icict/6088910.1016/j.mtcomm.2023.106357Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq). Fundação Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES).Federal University of Santa Catarina. Ceramic and Composite Materials Research Group. Florianopolis, SC, Brazil / Laboratory for High-Performance Ceramics. Swiss Federal Laboratories for Materials Science and Technology. Überlandstrasse, Dübendorf, Switzerland.Federal University of Santa Catarina. Ceramic and Composite Materials Research Group. Florianopolis, SC, Brazil.Laboratory for High-Performance Ceramics. Swiss Federal Laboratories for Materials Science and Technology. Überlandstrasse, Dübendorf, SwitzerlandOswaldo Cruz Foundation. Gonçalo Moniz Institute. Salvador, BA, Brasil.Oswaldo Cruz Foundation. Gonçalo Moniz Institute. Salvador, BA, Brasil.Federal University of Santa Catarina. Ceramic and Composite Materials Research Group. Florianopolis, SC, Brazil / Federal University of Santa Catarina. Interdisciplinary Laboratory for the Development of Nanostructures. Florianopolis, SC, Brazil.Federal University of Santa Catarina. Ceramic and Composite Materials Research Group. Florianopolis, SC, Brazil / Federal University of Santa Catarina. Interdisciplinary Laboratory for the Development of Nanostructures. Florianopolis, SC, Brazil.In this study, biocomposite filaments of polylactic acid (PLA) combined with stearic acid (SA)-coated nano-hydroxyapatite (HA) filler were prepared and characterized. These filaments were then used in material extrusion (MEX) additive manufacturing via fused deposition modeling (FDM) to create scaffolds for bone tissue engineering (BTE). Initially, HA was characterized using transmission electron microscopy (TEM), X-ray diffraction (XRD), and the Rietveld method. Particle size distribution was examined through dynamic light scattering (DLS), and its specific surface area was determined by the Brunauer-Emmett-Teller (BET) method. Subsequently, the HA nanoparticles were coated with stearic acid (SA) to explore its potential as a surfactant for PLA/HA nanocomposites. For composite fabrication, pure HA and SA-coated HA were mixed with PLA in a torque rheometer to obtain PLA/HA and PLA/HA-SA biocomposites. Their flow behavior was evaluated using a slit die rheometer, demonstrating that the SA coating improved rheological properties. The composites were extruded to produce 1.75 mm diameter filaments, which were analyzed by mechanical tensile testing, showing that the SA coating reduced the fragility of the PLA/HA filaments. The filaments exhibited high repeatability in terms of quality, facilitating scaffold printing. The FDM-manufactured scaffolds were analyzed through compressive testing, Fourier transform infrared (FTIR) spectroscopy, differential scanning calorimetry (DSC), and AlamarBlue Cell Viability Analysis. The results demonstrated that these scaffolds possess the required mechanical, thermal, and cytotoxicity properties for applications in bone tissue engineering.engElsevierBiocompósitosEngenharia de tecido ósseoAndaimesÁcido poliláticoNano-hidroxiapatitaÁcido esteáricoSurfactantes biocompatíveisModelagem de deposição fundidaBiocompositesBone tissue engineeringScaffoldsPolylactic acidNano-hydroxyapatiteStearic acidBiocompatible surfactantsFused deposition modelingEffect of stearic acid on the mechanical and rheological properties of PLA/ HA biocompositesinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/60889/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALAndrade, Júlia C. de - Effect of steric.pdfAndrade, Júlia C. de - Effect of steric.pdfapplication/pdf3530044https://www.arca.fiocruz.br/bitstream/icict/60889/2/Andrade%2c%20J%c3%balia%20C.%20de%20%20-%20Effect%20of%20steric.pdf950172157adbdb8a26ea030c3e86665dMD52icict/608892023-10-24 10:57:56.118oai:www.arca.fiocruz.br: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ório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352023-10-24T13:57:56Repositório Institucional da FIOCRUZ (ARCA) - 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dc.title.en_US.fl_str_mv Effect of stearic acid on the mechanical and rheological properties of PLA/ HA biocomposites
title Effect of stearic acid on the mechanical and rheological properties of PLA/ HA biocomposites
spellingShingle Effect of stearic acid on the mechanical and rheological properties of PLA/ HA biocomposites
Andrade, Júlia Cé de
Biocompósitos
Engenharia de tecido ósseo
Andaimes
Ácido polilático
Nano-hidroxiapatita
Ácido esteárico
Surfactantes biocompatíveis
Modelagem de deposição fundida
Biocomposites
Bone tissue engineering
Scaffolds
Polylactic acid
Nano-hydroxyapatite
Stearic acid
Biocompatible surfactants
Fused deposition modeling
title_short Effect of stearic acid on the mechanical and rheological properties of PLA/ HA biocomposites
title_full Effect of stearic acid on the mechanical and rheological properties of PLA/ HA biocomposites
title_fullStr Effect of stearic acid on the mechanical and rheological properties of PLA/ HA biocomposites
title_full_unstemmed Effect of stearic acid on the mechanical and rheological properties of PLA/ HA biocomposites
title_sort Effect of stearic acid on the mechanical and rheological properties of PLA/ HA biocomposites
author Andrade, Júlia Cé de
author_facet Andrade, Júlia Cé de
Cabral, Fernando
Clemens, Frank Jorg
Vieira, Jaqueline Leite
Soares, Milena B. P.
Hotza, Dachamir
Fredel, Márcio Celso
author_role author
author2 Cabral, Fernando
Clemens, Frank Jorg
Vieira, Jaqueline Leite
Soares, Milena B. P.
Hotza, Dachamir
Fredel, Márcio Celso
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Andrade, Júlia Cé de
Cabral, Fernando
Clemens, Frank Jorg
Vieira, Jaqueline Leite
Soares, Milena B. P.
Hotza, Dachamir
Fredel, Márcio Celso
dc.subject.other.en_US.fl_str_mv Biocompósitos
Engenharia de tecido ósseo
Andaimes
Ácido polilático
Nano-hidroxiapatita
Ácido esteárico
Surfactantes biocompatíveis
Modelagem de deposição fundida
topic Biocompósitos
Engenharia de tecido ósseo
Andaimes
Ácido polilático
Nano-hidroxiapatita
Ácido esteárico
Surfactantes biocompatíveis
Modelagem de deposição fundida
Biocomposites
Bone tissue engineering
Scaffolds
Polylactic acid
Nano-hydroxyapatite
Stearic acid
Biocompatible surfactants
Fused deposition modeling
dc.subject.en.en_US.fl_str_mv Biocomposites
Bone tissue engineering
Scaffolds
Polylactic acid
Nano-hydroxyapatite
Stearic acid
Biocompatible surfactants
Fused deposition modeling
description Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq). Fundação Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES).
publishDate 2023
dc.date.accessioned.fl_str_mv 2023-10-24T13:57:55Z
dc.date.available.fl_str_mv 2023-10-24T13:57:55Z
dc.date.issued.fl_str_mv 2023
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv ANDRADE, Júlia Cé de et al. Effect of stearic acid on the mechanical and rheological properties of PLA/ HA biocomposites. Materials Today Communications, v. 35, p. 1-7, 2023.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/60889
dc.identifier.issn.en_US.fl_str_mv 2352-4928
dc.identifier.doi.none.fl_str_mv 10.1016/j.mtcomm.2023.106357
identifier_str_mv ANDRADE, Júlia Cé de et al. Effect of stearic acid on the mechanical and rheological properties of PLA/ HA biocomposites. Materials Today Communications, v. 35, p. 1-7, 2023.
2352-4928
10.1016/j.mtcomm.2023.106357
url https://www.arca.fiocruz.br/handle/icict/60889
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/60889/1/license.txt
https://www.arca.fiocruz.br/bitstream/icict/60889/2/Andrade%2c%20J%c3%balia%20C.%20de%20%20-%20Effect%20of%20steric.pdf
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repository.mail.fl_str_mv repositorio.arca@fiocruz.br
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