Histopathologic features associated with susceptibility and resistance of Biomphalaria snails to infection with Schistosoma mansoni

Detalhes bibliográficos
Autor(a) principal: Borges, Claudia Maria da Cunha
Data de Publicação: 1998
Outros Autores: Souza, Cecília Pereira de, Andrade, Zilton de Araújo
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/5664
Resumo: Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil
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spelling Borges, Claudia Maria da CunhaSouza, Cecília Pereira deAndrade, Zilton de Araújo2012-10-15T19:09:17Z2012-10-15T19:09:17Z1998BORGES, C.M.; de SOUZA, C.P.; ANDRADE, Z.A. Histopathologic features associated with susceptibility and resistance of Biomphalaria snails to infection with Schistosoma mansoni. Memórias do Instituto Oswaldo Cruz, v. 93, Suppl 1, p. 117-21, 1998.0074-0276https://www.arca.fiocruz.br/handle/icict/5664engHistopathologic features associated with susceptibility and resistance of Biomphalaria snails to infection with Schistosoma mansoniinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, BrasilFundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Belo Horizonte, MG, BrasilFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, BrasilResistance and susceptibility of Biomphalaria snails to Schistosoma mansoni sporocysts occur in different degrees. Histopathology reflects these differences. In a state of tolerance numerous sporocysts in different stages of differentiation are seen in the absence of host tissue reaction. However extensive diffuse and focal proliferation of amebocytes with sequestration and destruction of many parasitic structures appear in resistant snails. Some snails are totally resistant and when exposed to infecting miracidia may never eliminate cercarie. Sequential histopathological examination has revealed that in such cases the infected miracidia are destroyed a few minutes to 24 hr after penetration in the snail. However, B. glabrata that were exposed to S. mansoni miracidia and three months later failed to shed cercariae, exhibited focal and diffuse proliferation of amebocytes in many organs in the absence of pasitic structures. These lesions were similar to those observed in resistant snails that were still eliminating a few cercariae, with the difference that no recognizable sporocystic structures or remnants were present. Histological investigation carried out in similarly resistant B. tenagophila and B. straminea presented essentially normal histologic structures. Only occasionally a few focal proliferative (granulomatous) amebocytic reactions were seen in ovotestis and in the tubular portion of the kidney. Probably, there are two types of reactions to miracidium presented by totally resistant snails: one would implicate the immediate destruction of the miracidium leaving no traces in the tissues; the other involving late reactions that seem to completely destroy invading sporocysts and leave histological changes.SnailsSchistosoma mansoni -SusceptibilityResistanceHistopathologyBiomphalaria/parasitologiaSchistosoma mansoni/patogenicidadeAnimaisBiomphalaria/fisiologiaInterações Hospedeiro-Parasita/fisiologiainfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZORIGINALBorges CM Histopathologic features associated....pdfBorges CM Histopathologic features associated....pdfapplication/pdf336065https://www.arca.fiocruz.br/bitstream/icict/5664/1/Borges%20CM%20Histopathologic%20features%20associated....pdf41b290ad7356696e0b6876628b1b4e7eMD51LICENSElicense.txtlicense.txttext/plain; charset=utf-82008https://www.arca.fiocruz.br/bitstream/icict/5664/2/license.txt06db3f0df647fd9ddff657403bbe0ee2MD52TEXTBorges CM Histopathologic features associated....pdf.txtBorges CM Histopathologic features associated....pdf.txtExtracted texttext/plain16072https://www.arca.fiocruz.br/bitstream/icict/5664/5/Borges%20CM%20Histopathologic%20features%20associated....pdf.txta5a408967d99d8b08e5634f4bf6b3245MD55THUMBNAILBorges CM Histopathologic features associated....pdf.jpgBorges CM Histopathologic features associated....pdf.jpgGenerated Thumbnailimage/jpeg2334https://www.arca.fiocruz.br/bitstream/icict/5664/4/Borges%20CM%20Histopathologic%20features%20associated....pdf.jpg4d5fc5e7b5e126f07ac238cba51a13e6MD54icict/56642023-03-15 14:32:59.901oai:www.arca.fiocruz.br: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Repositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352023-03-15T17:32:59Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv Histopathologic features associated with susceptibility and resistance of Biomphalaria snails to infection with Schistosoma mansoni
title Histopathologic features associated with susceptibility and resistance of Biomphalaria snails to infection with Schistosoma mansoni
spellingShingle Histopathologic features associated with susceptibility and resistance of Biomphalaria snails to infection with Schistosoma mansoni
Borges, Claudia Maria da Cunha
Snails
Schistosoma mansoni -
Susceptibility
Resistance
Histopathology
Biomphalaria/parasitologia
Schistosoma mansoni/patogenicidade
Animais
Biomphalaria/fisiologia
Interações Hospedeiro-Parasita/fisiologia
title_short Histopathologic features associated with susceptibility and resistance of Biomphalaria snails to infection with Schistosoma mansoni
title_full Histopathologic features associated with susceptibility and resistance of Biomphalaria snails to infection with Schistosoma mansoni
title_fullStr Histopathologic features associated with susceptibility and resistance of Biomphalaria snails to infection with Schistosoma mansoni
title_full_unstemmed Histopathologic features associated with susceptibility and resistance of Biomphalaria snails to infection with Schistosoma mansoni
title_sort Histopathologic features associated with susceptibility and resistance of Biomphalaria snails to infection with Schistosoma mansoni
author Borges, Claudia Maria da Cunha
author_facet Borges, Claudia Maria da Cunha
Souza, Cecília Pereira de
Andrade, Zilton de Araújo
author_role author
author2 Souza, Cecília Pereira de
Andrade, Zilton de Araújo
author2_role author
author
dc.contributor.author.fl_str_mv Borges, Claudia Maria da Cunha
Souza, Cecília Pereira de
Andrade, Zilton de Araújo
dc.subject.en.pt_BR.fl_str_mv Snails
Schistosoma mansoni -
Susceptibility
Resistance
Histopathology
topic Snails
Schistosoma mansoni -
Susceptibility
Resistance
Histopathology
Biomphalaria/parasitologia
Schistosoma mansoni/patogenicidade
Animais
Biomphalaria/fisiologia
Interações Hospedeiro-Parasita/fisiologia
dc.subject.decs.pt_BR.fl_str_mv Biomphalaria/parasitologia
Schistosoma mansoni/patogenicidade
Animais
Biomphalaria/fisiologia
Interações Hospedeiro-Parasita/fisiologia
description Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil
publishDate 1998
dc.date.issued.fl_str_mv 1998
dc.date.accessioned.fl_str_mv 2012-10-15T19:09:17Z
dc.date.available.fl_str_mv 2012-10-15T19:09:17Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv BORGES, C.M.; de SOUZA, C.P.; ANDRADE, Z.A. Histopathologic features associated with susceptibility and resistance of Biomphalaria snails to infection with Schistosoma mansoni. Memórias do Instituto Oswaldo Cruz, v. 93, Suppl 1, p. 117-21, 1998.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/5664
dc.identifier.issn.none.fl_str_mv 0074-0276
identifier_str_mv BORGES, C.M.; de SOUZA, C.P.; ANDRADE, Z.A. Histopathologic features associated with susceptibility and resistance of Biomphalaria snails to infection with Schistosoma mansoni. Memórias do Instituto Oswaldo Cruz, v. 93, Suppl 1, p. 117-21, 1998.
0074-0276
url https://www.arca.fiocruz.br/handle/icict/5664
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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