Evaluation of urine SARS-COV-2 RT-PCR as a predictor of acute kidney injury and disease severity in patients with critical COVID-19

Detalhes bibliográficos
Autor(a) principal: Souza, Sergio Pinto de
Data de Publicação: 2021
Outros Autores: Silveira, Marcelo Augusto Duarte, Souza, Bruno Solano de Freitas, Cabral, Julia Barros, Melo, Erica Batista dos Santos Galvão de, Nonaka, Carolina Kymie Vasques, Coelho, Fernanda Oliveira, Passos, Rogerio da Hora
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/47608
Resumo: Hospital São Rafael. Nefrologia. Salvador, BA, Brasil / Hospital Santo Antônio. Medicina Interna. Salvador, BA, Brasil / Escola Bahiana de Medicina e Saúde Pública. Salvador, BA, Brasil / Universidade Salvador. Salvador, BA, Brasil.
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spelling Souza, Sergio Pinto deSilveira, Marcelo Augusto DuarteSouza, Bruno Solano de FreitasCabral, Julia BarrosMelo, Erica Batista dos Santos Galvão deNonaka, Carolina Kymie VasquesCoelho, Fernanda OliveiraPassos, Rogerio da Hora2021-06-10T12:22:00Z2021-06-10T12:22:00Z2021SOUZA, Sergio Pinto de et al. Evaluation of urine SARS-COV-2 RT-PCR as a predictor of acute kidney injury and disease severity in patients with critical COVID-19. Journal of International Medical Research, v. 49, n. 5, p. 1-6, 14 May 2021.0300-0605https://www.arca.fiocruz.br/handle/icict/4760810.1177/030006052110155551473-2300engSAGE PublicationsUrinaSíndrome Respiratória Aguda GraveReação em cadeia da polimeraseLesão renal agudaCoronavírusTeste de vírusUrineSevere acute respiratory syndrome coronavirus 2Polymerase chain reactionAcute kidney injuryCoronavirus disease 2019Virus testingEvaluation of urine SARS-COV-2 RT-PCR as a predictor of acute kidney injury and disease severity in patients with critical COVID-19info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleHospital São Rafael. Nefrologia. Salvador, BA, Brasil / Hospital Santo Antônio. Medicina Interna. Salvador, BA, Brasil / Escola Bahiana de Medicina e Saúde Pública. Salvador, BA, Brasil / Universidade Salvador. Salvador, BA, Brasil.Hospital São Rafael. Nefrologia. Salvador, BA, Brasil.Hospital São Rafael. Centro de Biotecnologia e Terapia Celular. Salvador, BA, Brasil / Instituto D'Or de Ensino e Pesquisa. Rio de Janeiro, RJ, Brasil / Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil.Hospital São Rafael. Nefrologia. Salvador, BA, Brasil.Hospital São Rafael. Nefrologia. Salvador, BA, Brasil.Hospital São Rafael. Centro de Biotecnologia e Terapia Celular. Salvador, BA, Brasil.Hospital São Rafael. Nefrologia. Salvador, BA, Brasil.Hospital São Rafael. Nefrologia. Salvador, BA, Brasil.Coronavirus disease 2019 (COVID-19) is an emerging infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which began as an outbreak in Wuhan, China and has spread rapidly across the globe. Although most infections are mild, patients with severe and critical COVID-19 infections face deterioration of respiratory function and may also have extrapulmonary manifestations, mostly affecting the kidney, digestive tract, heart, and nervous system. Here, we prospectively evaluated the presence of SARS-CoV-2 genetic material using reverse-transcription polymerase chain reaction in urine samples obtained from patients with COVID-19 receiving critical care. Among 51 included patients, we found higher serum creatinine levels, a longer hospital stay, and more frequent need for dialysis in urine-positive patients. These findings could suggest that, in predisposed patients, a direct viral cytopathic effect may contribute to a more severe disease phenotype.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-83097https://www.arca.fiocruz.br/bitstream/icict/47608/1/license.txt36b51ef91c52b5338d9d29ba0cc807bcMD51ORIGINALSouza, Sergio Pinto Evaluation....pdfSouza, Sergio Pinto Evaluation....pdfapplication/pdf253821https://www.arca.fiocruz.br/bitstream/icict/47608/2/Souza%2c%20Sergio%20Pinto%20Evaluation....pdf22ad1baefc84c713fb4586eb9ff0d695MD52TEXTSouza, Sergio Pinto Evaluation....pdf.txtSouza, Sergio Pinto Evaluation....pdf.txtExtracted texttext/plain16453https://www.arca.fiocruz.br/bitstream/icict/47608/3/Souza%2c%20Sergio%20Pinto%20Evaluation....pdf.txtbd58918b2611c051804763e2062e3208MD53icict/476082023-03-15 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dc.title.en.fl_str_mv Evaluation of urine SARS-COV-2 RT-PCR as a predictor of acute kidney injury and disease severity in patients with critical COVID-19
title Evaluation of urine SARS-COV-2 RT-PCR as a predictor of acute kidney injury and disease severity in patients with critical COVID-19
spellingShingle Evaluation of urine SARS-COV-2 RT-PCR as a predictor of acute kidney injury and disease severity in patients with critical COVID-19
Souza, Sergio Pinto de
Urina
Síndrome Respiratória Aguda Grave
Reação em cadeia da polimerase
Lesão renal aguda
Coronavírus
Teste de vírus
Urine
Severe acute respiratory syndrome coronavirus 2
Polymerase chain reaction
Acute kidney injury
Coronavirus disease 2019
Virus testing
title_short Evaluation of urine SARS-COV-2 RT-PCR as a predictor of acute kidney injury and disease severity in patients with critical COVID-19
title_full Evaluation of urine SARS-COV-2 RT-PCR as a predictor of acute kidney injury and disease severity in patients with critical COVID-19
title_fullStr Evaluation of urine SARS-COV-2 RT-PCR as a predictor of acute kidney injury and disease severity in patients with critical COVID-19
title_full_unstemmed Evaluation of urine SARS-COV-2 RT-PCR as a predictor of acute kidney injury and disease severity in patients with critical COVID-19
title_sort Evaluation of urine SARS-COV-2 RT-PCR as a predictor of acute kidney injury and disease severity in patients with critical COVID-19
author Souza, Sergio Pinto de
author_facet Souza, Sergio Pinto de
Silveira, Marcelo Augusto Duarte
Souza, Bruno Solano de Freitas
Cabral, Julia Barros
Melo, Erica Batista dos Santos Galvão de
Nonaka, Carolina Kymie Vasques
Coelho, Fernanda Oliveira
Passos, Rogerio da Hora
author_role author
author2 Silveira, Marcelo Augusto Duarte
Souza, Bruno Solano de Freitas
Cabral, Julia Barros
Melo, Erica Batista dos Santos Galvão de
Nonaka, Carolina Kymie Vasques
Coelho, Fernanda Oliveira
Passos, Rogerio da Hora
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Souza, Sergio Pinto de
Silveira, Marcelo Augusto Duarte
Souza, Bruno Solano de Freitas
Cabral, Julia Barros
Melo, Erica Batista dos Santos Galvão de
Nonaka, Carolina Kymie Vasques
Coelho, Fernanda Oliveira
Passos, Rogerio da Hora
dc.subject.other.pt_BR.fl_str_mv Urina
Síndrome Respiratória Aguda Grave
Reação em cadeia da polimerase
Lesão renal aguda
Coronavírus
Teste de vírus
topic Urina
Síndrome Respiratória Aguda Grave
Reação em cadeia da polimerase
Lesão renal aguda
Coronavírus
Teste de vírus
Urine
Severe acute respiratory syndrome coronavirus 2
Polymerase chain reaction
Acute kidney injury
Coronavirus disease 2019
Virus testing
dc.subject.en.en.fl_str_mv Urine
Severe acute respiratory syndrome coronavirus 2
Polymerase chain reaction
Acute kidney injury
Coronavirus disease 2019
Virus testing
description Hospital São Rafael. Nefrologia. Salvador, BA, Brasil / Hospital Santo Antônio. Medicina Interna. Salvador, BA, Brasil / Escola Bahiana de Medicina e Saúde Pública. Salvador, BA, Brasil / Universidade Salvador. Salvador, BA, Brasil.
publishDate 2021
dc.date.accessioned.fl_str_mv 2021-06-10T12:22:00Z
dc.date.available.fl_str_mv 2021-06-10T12:22:00Z
dc.date.issued.fl_str_mv 2021
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv SOUZA, Sergio Pinto de et al. Evaluation of urine SARS-COV-2 RT-PCR as a predictor of acute kidney injury and disease severity in patients with critical COVID-19. Journal of International Medical Research, v. 49, n. 5, p. 1-6, 14 May 2021.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/47608
dc.identifier.issn.pt_BR.fl_str_mv 0300-0605
dc.identifier.doi.pt_BR.fl_str_mv 10.1177/03000605211015555
dc.identifier.eissn.pt_BR.fl_str_mv 1473-2300
identifier_str_mv SOUZA, Sergio Pinto de et al. Evaluation of urine SARS-COV-2 RT-PCR as a predictor of acute kidney injury and disease severity in patients with critical COVID-19. Journal of International Medical Research, v. 49, n. 5, p. 1-6, 14 May 2021.
0300-0605
10.1177/03000605211015555
1473-2300
url https://www.arca.fiocruz.br/handle/icict/47608
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv SAGE Publications
publisher.none.fl_str_mv SAGE Publications
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/47608/1/license.txt
https://www.arca.fiocruz.br/bitstream/icict/47608/2/Souza%2c%20Sergio%20Pinto%20Evaluation....pdf
https://www.arca.fiocruz.br/bitstream/icict/47608/3/Souza%2c%20Sergio%20Pinto%20Evaluation....pdf.txt
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