Respiratory syncytial virus a and b display different temporal patterns in a 4-year prospective cross-sectional study among children with acute respiratory infection in a tropical city
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2016 |
| Outros Autores: | , , , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
| Texto Completo: | https://www.arca.fiocruz.br/handle/icict/18072 |
Resumo: | Bahia State Agency for Research Funding (FAPESB) [grant numbers APP0045/2009 and PNX0019/2009]. FAPESB had no role in study design, data collection, data analysis, data interpretation, or writing of the report. |
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Bouzas, Maiara Lanna Souza BacelarOliveira, Juliana RFukutani, Kiyoshi FerreiraBorges, Igor CarmoBarral, Aldina Maria PradoGucht, Winke Van derWollants, ElkeVan Ranst, MarcOliveira, Camila Indiani deVan Weyenbergh, Johan Jozef Rosa MariaCarvalho, Cristiana Maria Costa NascimentoThe Acute Respiratory Infection, Wheeze Study Group Phase I, II2017-03-17T14:22:59Z2017-03-17T14:22:59Z2016BOUZAS, M. L. S. B. et al. Respiratory syncytial virus a and b display different temporal patterns in a 4-year prospective cross-sectional study among children with acute respiratory infection in a tropical city. Medicine, v. 95, p. 41, 2016.0025-7974https://www.arca.fiocruz.br/handle/icict/1807210.1097/MD.0000000000005142Bahia State Agency for Research Funding (FAPESB) [grant numbers APP0045/2009 and PNX0019/2009]. FAPESB had no role in study design, data collection, data analysis, data interpretation, or writing of the report.Federal University of Bahia. School of Medicine. Salvador, BA, BrazilFederal University of Bahia. School of Medicine. Salvador, BA, BrazilFederal University of Bahia. School of Medicine. Salvador, BA, BrazilFederal University of Bahia. School of Medicine. Salvador, BA, BrazilFederal University of Bahia. School of Medicine., Salvador, BA, Brazil / Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil / Federal University of Bahia. School of Medicine. Department of Pathology. Salvador, BA, BraziRega Institute for Medical Research. Laboratory for Clinical and Epidemiological Virology. Department of Microbiology and Immunology. KU, Leuven, BelgiumRega Institute for Medical Research. Laboratory for Clinical and Epidemiological Virology. Department of Microbiology and Immunology. KU, Leuven, BelgiumRega Institute for Medical Research. Laboratory for Clinical and Epidemiological Virology. Department of Microbiology and Immunology. KU, Leuven, BelgiumFederal University of Bahia. School of Medicine. Salvador, BA, Brazil / Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, BrasilRega Institute for Medical Research. Laboratory for Clinical and Epidemiological Virology. Department of Microbiology and Immunology. KU, Leuven, BelgiumFederal University of Bahia. School of Medicine. Salvador, BA, Brazil / Federal University of Bahia. School of Medicine. Department of Pediatrics. Salvador, BA, BrazilRespiratory syncytial virus (RSV) is one of the most common etiological agents of childhood respiratory infections globally. Information on seasonality of different antigenic groups is scarce. We aimed to describe the frequency, seasonality, and age of children infected by RSV antigenic groups A (RSVA) and B (RSVB) among children with ARI in a 4-year period.Children (6-23 months old) with respiratory infection for ≤7 days were enrolled in a prospective cross-sectional study, from September, 2009 to October, 2013, in Salvador, in a tropical region of Brazil. Upon recruitment, demographic, clinical data, and nasopharyngeal aspirates (NPA) were collected. A multiplex quantitative real-time polymerase chain reaction (RT-PCR) with a group-specific primer and probeset for RSVA and RSVB was used. Seasonal distribution of infection by RSV different antigenic groups was evaluated by Prais-Wisten regression.Of 560 cases, the mean age was 11.4 ± 4.5 months and there were 287 (51.3%) girls. Overall, RSV was detected in 139 (24.8%; 95% CI: 21.4%-28.5%) cases, RSVA in 74 (13.2%; 95% CI: 10.6%-16.2%) cases, and RSVB in 67 (12.0%; 95% CI: 9.5%-14.9%) cases. Two (0.4%; 95% CI: 0.06%-1.2%) cases had coinfection. RSVA frequency was 9.6%, 18.4%, 21.6%, and 3.1% in 2010, 2011, 2012, and 2013, respectively. RSVB frequency was 19.2%, 0.7%, 1.4%, and 35.4% in the same years. RSVA was more frequently found from August to January than February to July (18.2% vs. 6.4%, P < 0.001). RSVB was more frequently found (P < 0.001) between March and June (36.0%) than July to October (1.0%) or November to February (1.6%). RSVB infection showed seasonal distribution and positive association with humidity (P = 0.02) whereas RSVA did not. RSVA was more common among children ≥1-year-old (17.8% vs. 1.8%; P = 0.02), as opposed to RSVB (11.5% vs. 12.2%; P = 0.8).One quarter of patients had RSV infection. RSVA compromised more frequently children aged ≥1 year. RSVA predominated in 2011 and 2012 whereas RSVB predominated in 2010 and 2013. In regard to months, RSVA was more frequent from August to January whereas RSVB was more often detected between March and June. Markedly different monthly as well as yearly patterns for RSVA and RSVB reveal independent RSV antigenic groups' epidemics.engWillams & WilkinsInfecção respiratória agudaImunoprofilaxiaRSVRSVARSVBSazonalidadeAcute respiratory infectionImmunoprophylaxisPalivizumabRSVRSVARSVBSeasonalityRespiratory syncytial virus a and b display different temporal patterns in a 4-year prospective cross-sectional study among children with acute respiratory infection in a tropical cityinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/18072/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALBouzas ML Respiractory....pdfBouzas ML 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| dc.title.pt_BR.fl_str_mv |
Respiratory syncytial virus a and b display different temporal patterns in a 4-year prospective cross-sectional study among children with acute respiratory infection in a tropical city |
| title |
Respiratory syncytial virus a and b display different temporal patterns in a 4-year prospective cross-sectional study among children with acute respiratory infection in a tropical city |
| spellingShingle |
Respiratory syncytial virus a and b display different temporal patterns in a 4-year prospective cross-sectional study among children with acute respiratory infection in a tropical city Bouzas, Maiara Lanna Souza Bacelar Infecção respiratória aguda Imunoprofilaxia RSV RSVA RSVB Sazonalidade Acute respiratory infection Immunoprophylaxis Palivizumab RSV RSVA RSVB Seasonality |
| title_short |
Respiratory syncytial virus a and b display different temporal patterns in a 4-year prospective cross-sectional study among children with acute respiratory infection in a tropical city |
| title_full |
Respiratory syncytial virus a and b display different temporal patterns in a 4-year prospective cross-sectional study among children with acute respiratory infection in a tropical city |
| title_fullStr |
Respiratory syncytial virus a and b display different temporal patterns in a 4-year prospective cross-sectional study among children with acute respiratory infection in a tropical city |
| title_full_unstemmed |
Respiratory syncytial virus a and b display different temporal patterns in a 4-year prospective cross-sectional study among children with acute respiratory infection in a tropical city |
| title_sort |
Respiratory syncytial virus a and b display different temporal patterns in a 4-year prospective cross-sectional study among children with acute respiratory infection in a tropical city |
| author |
Bouzas, Maiara Lanna Souza Bacelar |
| author_facet |
Bouzas, Maiara Lanna Souza Bacelar Oliveira, Juliana R Fukutani, Kiyoshi Ferreira Borges, Igor Carmo Barral, Aldina Maria Prado Gucht, Winke Van der Wollants, Elke Van Ranst, Marc Oliveira, Camila Indiani de Van Weyenbergh, Johan Jozef Rosa Maria Carvalho, Cristiana Maria Costa Nascimento The Acute Respiratory Infection, Wheeze Study Group Phase I, II |
| author_role |
author |
| author2 |
Oliveira, Juliana R Fukutani, Kiyoshi Ferreira Borges, Igor Carmo Barral, Aldina Maria Prado Gucht, Winke Van der Wollants, Elke Van Ranst, Marc Oliveira, Camila Indiani de Van Weyenbergh, Johan Jozef Rosa Maria Carvalho, Cristiana Maria Costa Nascimento The Acute Respiratory Infection, Wheeze Study Group Phase I, II |
| author2_role |
author author author author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Bouzas, Maiara Lanna Souza Bacelar Oliveira, Juliana R Fukutani, Kiyoshi Ferreira Borges, Igor Carmo Barral, Aldina Maria Prado Gucht, Winke Van der Wollants, Elke Van Ranst, Marc Oliveira, Camila Indiani de Van Weyenbergh, Johan Jozef Rosa Maria Carvalho, Cristiana Maria Costa Nascimento The Acute Respiratory Infection, Wheeze Study Group Phase I, II |
| dc.subject.other.pt_BR.fl_str_mv |
Infecção respiratória aguda Imunoprofilaxia RSV RSVA RSVB Sazonalidade |
| topic |
Infecção respiratória aguda Imunoprofilaxia RSV RSVA RSVB Sazonalidade Acute respiratory infection Immunoprophylaxis Palivizumab RSV RSVA RSVB Seasonality |
| dc.subject.en.pt_BR.fl_str_mv |
Acute respiratory infection Immunoprophylaxis Palivizumab RSV RSVA RSVB Seasonality |
| description |
Bahia State Agency for Research Funding (FAPESB) [grant numbers APP0045/2009 and PNX0019/2009]. FAPESB had no role in study design, data collection, data analysis, data interpretation, or writing of the report. |
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2016 |
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2016 |
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2017-03-17T14:22:59Z |
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2017-03-17T14:22:59Z |
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info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
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BOUZAS, M. L. S. B. et al. Respiratory syncytial virus a and b display different temporal patterns in a 4-year prospective cross-sectional study among children with acute respiratory infection in a tropical city. Medicine, v. 95, p. 41, 2016. |
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https://www.arca.fiocruz.br/handle/icict/18072 |
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0025-7974 |
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10.1097/MD.0000000000005142 |
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BOUZAS, M. L. S. B. et al. Respiratory syncytial virus a and b display different temporal patterns in a 4-year prospective cross-sectional study among children with acute respiratory infection in a tropical city. Medicine, v. 95, p. 41, 2016. 0025-7974 10.1097/MD.0000000000005142 |
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Willams & Wilkins |
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Willams & Wilkins |
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