Detection of Hepatitis C Virus RNA in Saliva Is Not Related to Oral Health Status or Viral Load

Detalhes bibliográficos
Autor(a) principal: Lins, Liliane
Data de Publicação: 2005
Outros Autores: Almeida, Herbert, Vitvitski, Ludmila, Carmo, Theomira Mauadie de Azevedo, Paraná, Raymundo, Reis, Mitermayer Galvão dos
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/2785
Resumo: Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil
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spelling Lins, LilianeAlmeida, HerbertVitvitski, LudmilaCarmo, Theomira Mauadie de AzevedoParaná, RaymundoReis, Mitermayer Galvão dos2011-07-28T18:27:28Z2011-07-28T18:27:28Z2005LINS, L. et al. Detection of hepatitis C virus RNA in saliva is not related to oral health status or viral load. Journal of Medical Virology, v. 77, n. 2, p. 216-220, 2005.0146-6615https://www.arca.fiocruz.br/handle/icict/278510.1002/jmv.20438engHepacivirusRNA ViralSalivaAnticorpos Anti-HepatiteGenes ViraisCarga ViralHepacivirusRNA ViralSalivaAnticorpos Anti-HepatiteDetection of Hepatitis C Virus RNA in Saliva Is Not Related to Oral Health Status or Viral Loadinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, BrasilUniversidade Federal da Bahia. Faculdade de Medicina. Salvador, BA, BrazilINSERM U271. Lyon, FranceFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, BrasilUniversidade Federal da Bahia. Faculdade de Medicina. Salvador, BA, BrazilFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, BrasilHepatitis C is a worldwide public health problem and its transmission is clearly associated with the parenteral route, however, the virus has also been isolated from other body fluids. Hepatitis C virus (HCV) RNA has been detected in saliva, yet the relationship between HCV and oral pathology is not clearly understood. Therefore, an investigation on HCV-RNA in saliva and its correlation with oral pathology was undertaken. Saliva and blood samples were collected from 50 anti-HCV positive patients and from 25 patients with non-HCV chronic liver disease. HCV-RNA was detected in all of the saliva samples from the HCV positive group. None of the saliva or serum samples from the non-HCV group were positive for HCV-RNA. The patients were examined for dental and oral health (dentate, partially dentate, edentulous, evidence of gum disease, or mucosal lesions); however, no correlation was found between HCV-RNA in saliva, oral health, and viral load. These results suggest that HCV-RNA presence in saliva is independent of the viral load and the oral pathology of HCV positive individualsinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZORIGINALLins L Detection of hepatitis C virus....pdfLins L Detection of hepatitis C virus....pdfapplication/pdf90877https://www.arca.fiocruz.br/bitstream/icict/2785/1/Lins%20L%20Detection%20of%20hepatitis%20C%20virus....pdfee233685ab67836fa1632e6a53a2d76bMD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81648https://www.arca.fiocruz.br/bitstream/icict/2785/2/license.txte095249ac7cacefbfe39684dfe45e706MD52TEXTLins L Detection of hepatitis C virus....pdf.txtLins L Detection of hepatitis C virus....pdf.txtExtracted texttext/plain22456https://www.arca.fiocruz.br/bitstream/icict/2785/5/Lins%20L%20Detection%20of%20hepatitis%20C%20virus....pdf.txtd4dfcdb41aa8456b00e8f5c1a85b400bMD55THUMBNAILLins L Detection of hepatitis C virus....pdf.jpgLins L Detection of hepatitis C virus....pdf.jpgGenerated Thumbnailimage/jpeg2263https://www.arca.fiocruz.br/bitstream/icict/2785/4/Lins%20L%20Detection%20of%20hepatitis%20C%20virus....pdf.jpgd2602eb75fc424d526044ba9848edd93MD54icict/27852023-03-15 14:33:00.364oai:www.arca.fiocruz.br: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Repositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352023-03-15T17:33Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv Detection of Hepatitis C Virus RNA in Saliva Is Not Related to Oral Health Status or Viral Load
title Detection of Hepatitis C Virus RNA in Saliva Is Not Related to Oral Health Status or Viral Load
spellingShingle Detection of Hepatitis C Virus RNA in Saliva Is Not Related to Oral Health Status or Viral Load
Lins, Liliane
Hepacivirus
RNA Viral
Saliva
Anticorpos Anti-Hepatite
Genes Virais
Carga Viral
Hepacivirus
RNA Viral
Saliva
Anticorpos Anti-Hepatite
title_short Detection of Hepatitis C Virus RNA in Saliva Is Not Related to Oral Health Status or Viral Load
title_full Detection of Hepatitis C Virus RNA in Saliva Is Not Related to Oral Health Status or Viral Load
title_fullStr Detection of Hepatitis C Virus RNA in Saliva Is Not Related to Oral Health Status or Viral Load
title_full_unstemmed Detection of Hepatitis C Virus RNA in Saliva Is Not Related to Oral Health Status or Viral Load
title_sort Detection of Hepatitis C Virus RNA in Saliva Is Not Related to Oral Health Status or Viral Load
author Lins, Liliane
author_facet Lins, Liliane
Almeida, Herbert
Vitvitski, Ludmila
Carmo, Theomira Mauadie de Azevedo
Paraná, Raymundo
Reis, Mitermayer Galvão dos
author_role author
author2 Almeida, Herbert
Vitvitski, Ludmila
Carmo, Theomira Mauadie de Azevedo
Paraná, Raymundo
Reis, Mitermayer Galvão dos
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Lins, Liliane
Almeida, Herbert
Vitvitski, Ludmila
Carmo, Theomira Mauadie de Azevedo
Paraná, Raymundo
Reis, Mitermayer Galvão dos
dc.subject.other.pt_BR.fl_str_mv Hepacivirus
RNA Viral
Saliva
Anticorpos Anti-Hepatite
Genes Virais
Carga Viral
topic Hepacivirus
RNA Viral
Saliva
Anticorpos Anti-Hepatite
Genes Virais
Carga Viral
Hepacivirus
RNA Viral
Saliva
Anticorpos Anti-Hepatite
dc.subject.decs.pt_BR.fl_str_mv Hepacivirus
RNA Viral
Saliva
Anticorpos Anti-Hepatite
description Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil
publishDate 2005
dc.date.issued.fl_str_mv 2005
dc.date.accessioned.fl_str_mv 2011-07-28T18:27:28Z
dc.date.available.fl_str_mv 2011-07-28T18:27:28Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv LINS, L. et al. Detection of hepatitis C virus RNA in saliva is not related to oral health status or viral load. Journal of Medical Virology, v. 77, n. 2, p. 216-220, 2005.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/2785
dc.identifier.issn.none.fl_str_mv 0146-6615
dc.identifier.doi.none.fl_str_mv 10.1002/jmv.20438
identifier_str_mv LINS, L. et al. Detection of hepatitis C virus RNA in saliva is not related to oral health status or viral load. Journal of Medical Virology, v. 77, n. 2, p. 216-220, 2005.
0146-6615
10.1002/jmv.20438
url https://www.arca.fiocruz.br/handle/icict/2785
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