Revisiting the Rich's formula: an update about granulomas in human tuberculosis

Detalhes bibliográficos
Autor(a) principal: Coelho Filho, João Carlos
Data de Publicação: 2013
Outros Autores: Takenami, Iukary, Arruda, Sérgio Marcos
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/24947
Resumo: Fundação José Silveira. Laboratório de Patologia. Salvador, BA, Brazil
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spelling Coelho Filho, João CarlosTakenami, IukaryArruda, Sérgio Marcos2018-02-26T18:09:00Z2018-02-26T18:09:00Z2013COELHO FILHO, J. C.; TAKENAMI, I.; ARRUDA, S. M. Revisiting the Rich's formula: an update about granulomas in human tuberculosis. Brazilian Journal of Infectious Diseases, v. 17, n. 2, p. 234–238, 2013.1413-8670https://www.arca.fiocruz.br/handle/icict/2494710.1016/j.bjid.2013.01.006engElsevierFórmula de RichTuberculoseImunopatogêneseGranulomaHipersensibilidadeRich’s formulaTuberculosisImmunopathogenesisGranulomaHypersensitivityRevisiting the Rich's formula: an update about granulomas in human tuberculosisinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação José Silveira. Laboratório de Patologia. Salvador, BA, BrazilFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Laboratório Avançado de Saúde Pública. Salvador, BA, BrasilFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Laboratório Avançado de Saúde Pública. Salvador, BA, BrasilThe formula proposed by Rich in 1951 explained the formation in a tuberculous lesion in a period that was unknown cellular functions, cytokines and other immunological aspects involved in granuloma formation by tuberculosis; its components are assembled conceptually to explain the pathogenic mechanisms involved in the granulomatous lesion in tuberculosis. In this manuscript, we report an update of Rich's formula based on the new and old concepts about pathogenic mechanisms involved in the granulomatous lesion in tuberculosis. Current knowledge allows us to conclude that the balance between the characteristics of the bacillus and host protective response is necessary to indicate the outcome of pathogenesis, infection or active disease and the necrosis degree of the tuberculosis lesion.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/24947/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALCoelho Filho JC Revisiting the Rich's formula....pdfCoelho Filho JC Revisiting the Rich's formula....pdfapplication/pdf237785https://www.arca.fiocruz.br/bitstream/icict/24947/2/Coelho%20Filho%20JC%20Revisiting%20the%20Rich%27s%20formula....pdf662d960a30c668a0256d94cd46d22ec3MD52TEXTCoelho Filho JC Revisiting the Rich's formula....pdf.txtCoelho Filho JC Revisiting the Rich's formula....pdf.txtExtracted 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dc.title.pt_BR.fl_str_mv Revisiting the Rich's formula: an update about granulomas in human tuberculosis
title Revisiting the Rich's formula: an update about granulomas in human tuberculosis
spellingShingle Revisiting the Rich's formula: an update about granulomas in human tuberculosis
Coelho Filho, João Carlos
Fórmula de Rich
Tuberculose
Imunopatogênese
Granuloma
Hipersensibilidade
Rich’s formula
Tuberculosis
Immunopathogenesis
Granuloma
Hypersensitivity
title_short Revisiting the Rich's formula: an update about granulomas in human tuberculosis
title_full Revisiting the Rich's formula: an update about granulomas in human tuberculosis
title_fullStr Revisiting the Rich's formula: an update about granulomas in human tuberculosis
title_full_unstemmed Revisiting the Rich's formula: an update about granulomas in human tuberculosis
title_sort Revisiting the Rich's formula: an update about granulomas in human tuberculosis
author Coelho Filho, João Carlos
author_facet Coelho Filho, João Carlos
Takenami, Iukary
Arruda, Sérgio Marcos
author_role author
author2 Takenami, Iukary
Arruda, Sérgio Marcos
author2_role author
author
dc.contributor.author.fl_str_mv Coelho Filho, João Carlos
Takenami, Iukary
Arruda, Sérgio Marcos
dc.subject.other.pt_BR.fl_str_mv Fórmula de Rich
Tuberculose
Imunopatogênese
Granuloma
Hipersensibilidade
topic Fórmula de Rich
Tuberculose
Imunopatogênese
Granuloma
Hipersensibilidade
Rich’s formula
Tuberculosis
Immunopathogenesis
Granuloma
Hypersensitivity
dc.subject.en.pt_BR.fl_str_mv Rich’s formula
Tuberculosis
Immunopathogenesis
Granuloma
Hypersensitivity
description Fundação José Silveira. Laboratório de Patologia. Salvador, BA, Brazil
publishDate 2013
dc.date.issued.fl_str_mv 2013
dc.date.accessioned.fl_str_mv 2018-02-26T18:09:00Z
dc.date.available.fl_str_mv 2018-02-26T18:09:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv COELHO FILHO, J. C.; TAKENAMI, I.; ARRUDA, S. M. Revisiting the Rich's formula: an update about granulomas in human tuberculosis. Brazilian Journal of Infectious Diseases, v. 17, n. 2, p. 234–238, 2013.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/24947
dc.identifier.issn.pt_BR.fl_str_mv 1413-8670
dc.identifier.doi.none.fl_str_mv 10.1016/j.bjid.2013.01.006
identifier_str_mv COELHO FILHO, J. C.; TAKENAMI, I.; ARRUDA, S. M. Revisiting the Rich's formula: an update about granulomas in human tuberculosis. Brazilian Journal of Infectious Diseases, v. 17, n. 2, p. 234–238, 2013.
1413-8670
10.1016/j.bjid.2013.01.006
url https://www.arca.fiocruz.br/handle/icict/24947
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
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instacron_str FIOCRUZ
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reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
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