Mar, a MITE family of hAT transposons in Drosophila

Detalhes bibliográficos
Autor(a) principal: Deprá, Maríndia
Data de Publicação: 2012
Outros Autores: Ludwig, Adriana, Valente, Vera L. S., Loreto, Elgion L. S.
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/29017
Resumo: Universidade Federal do Rio Grande do Sul. Departamento de Genética. Programa de Pós-Graduação em Genética e Biologia Molecular. Porto Alegre, RS, Brasil / Universidade Federal do Rio Grande do Sul. Departamento de Zoologia. Programa de Pós-Graduação em Biologia Animal. Porto Alegre, RS, Brasil.
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spelling Deprá, MaríndiaLudwig, AdrianaValente, Vera L. S.Loreto, Elgion L. S.2018-09-24T18:06:10Z2018-09-24T18:06:10Z2012DEPRÁ, Maríndia et al. Mar, a MITE family of hAT transposons in Drosophila. Mobile DNA, v. 3, n. 13, p. 1-12, 2012.1759-8753https://www.arca.fiocruz.br/handle/icict/2901710.1186/1759-8753-3-131759-8753porBMCDrosophilaMAR ElementsDrosophilidaeTransposasesMatrix Attachment RegionsTransposasasRegiones de Fijación a la MatrizTransposasesRegiões de Interação com a MatrizMar, a MITE family of hAT transposons in Drosophilainfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidade Federal do Rio Grande do Sul. Departamento de Genética. Programa de Pós-Graduação em Genética e Biologia Molecular. Porto Alegre, RS, Brasil / Universidade Federal do Rio Grande do Sul. Departamento de Zoologia. Programa de Pós-Graduação em Biologia Animal. Porto Alegre, RS, Brasil.Universidade Federal do Rio Grande do Sul. Departamento de Genética. Programa de Pós-Graduação em Genética e Biologia Molecular. Porto Alegre, RS, Brasil / Fundação Oswaldo Cruz. Instituto Carlos Chagas. Curitiba, PR, Brasil / Pontifícia Universidade Católica do Paraná. Curitiba, PR, Brasil.Universidade Federal do Rio Grande do Sul. Departamento de Genética. Programa de Pós-Graduação em Genética e Biologia Molecular. Porto Alegre, RS, Brasil / Universidade Federal do Rio Grande do Sul. Departamento de Zoologia. Programa de Pós-Graduação em Biologia Animal. Porto Alegre, RS, Brasil.Universidade Federal do Rio Grande do Sul. Departamento de Genética. Programa de Pós-Graduação em Genética e Biologia Molecular. Porto Alegre, RS, Brasil / Universidade Federal de Santa Maria. Departamento de Biologia. Santa Maria, RS, Brasil.Miniature inverted-repeat transposable elements (MITEs) are short, nonautonomous DNA elements flanked by subterminal or terminal inverted repeats (TIRs) with no coding capacity. MITEs were originally recognized as important components of plant genomes, where they can attain extremely high copy numbers, and are also found in several animal genomes, including mosquitoes, fish and humans. So far, few MITEs have been described in Drosophila. As results, here in we describe the distribution and evolution of Mar, a MITE family of hAT transposons, in Drosophilidae species. In silico searches and PCR screening showed that Mar distribution is restricted to the willistoni subgroup of the Drosophila species, and a phylogenetic analysis of Mar indicates that this element may have originated prior to the diversification of these species. Most of the Mar copies in D. willistoni present conserved target site duplications and TIRs, indicating recent mobilization of these sequences. We also identified relic copies of potentially full-length Mar transposon in D. tropicalis and D. willistoni. The phylogenetic relationship among transposases from the putative full-length Mar and other hAT superfamily elements revealed that Mar is placed into the recently determined Buster group of hAT transposons. We have as conclusion that on the basis of the obtained data, we can suggest that the origin of these Mar MITEs occurred before the subgroup willistoni speciation, which started about 5.7 Mya. The Mar relic transposase existence indicates that these MITEs originated by internal deletions and suggests that the full-length transposon was recently functional in D. willistoni, promoting Mar MITEs mobilization.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-83084https://www.arca.fiocruz.br/bitstream/icict/29017/1/license.txt783568c2893d2e25a99990b126be1772MD51ORIGINALMobileDNA8753-3-13.pdfMobileDNA8753-3-13.pdfapplication/pdf1967837https://www.arca.fiocruz.br/bitstream/icict/29017/2/MobileDNA8753-3-13.pdf1303d81cceabd983a3a7c01b4044d3d2MD52TEXTMobileDNA8753-3-13.pdf.txtMobileDNA8753-3-13.pdf.txtExtracted texttext/plain44711https://www.arca.fiocruz.br/bitstream/icict/29017/3/MobileDNA8753-3-13.pdf.txt87cd4592e29c359e3b1c95345dc31211MD53icict/290172019-12-15 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dc.title.pt_BR.fl_str_mv Mar, a MITE family of hAT transposons in Drosophila
title Mar, a MITE family of hAT transposons in Drosophila
spellingShingle Mar, a MITE family of hAT transposons in Drosophila
Deprá, Maríndia
Drosophila
MAR Elements
Drosophilidae
Transposases
Matrix Attachment Regions
Transposasas
Regiones de Fijación a la Matriz
Transposases
Regiões de Interação com a Matriz
title_short Mar, a MITE family of hAT transposons in Drosophila
title_full Mar, a MITE family of hAT transposons in Drosophila
title_fullStr Mar, a MITE family of hAT transposons in Drosophila
title_full_unstemmed Mar, a MITE family of hAT transposons in Drosophila
title_sort Mar, a MITE family of hAT transposons in Drosophila
author Deprá, Maríndia
author_facet Deprá, Maríndia
Ludwig, Adriana
Valente, Vera L. S.
Loreto, Elgion L. S.
author_role author
author2 Ludwig, Adriana
Valente, Vera L. S.
Loreto, Elgion L. S.
author2_role author
author
author
dc.contributor.author.fl_str_mv Deprá, Maríndia
Ludwig, Adriana
Valente, Vera L. S.
Loreto, Elgion L. S.
dc.subject.other.pt_BR.fl_str_mv Drosophila
MAR Elements
Drosophilidae
topic Drosophila
MAR Elements
Drosophilidae
Transposases
Matrix Attachment Regions
Transposasas
Regiones de Fijación a la Matriz
Transposases
Regiões de Interação com a Matriz
dc.subject.en.pt_BR.fl_str_mv Transposases
Matrix Attachment Regions
dc.subject.es.pt_BR.fl_str_mv Transposasas
Regiones de Fijación a la Matriz
dc.subject.decs.pt_BR.fl_str_mv Transposases
Regiões de Interação com a Matriz
description Universidade Federal do Rio Grande do Sul. Departamento de Genética. Programa de Pós-Graduação em Genética e Biologia Molecular. Porto Alegre, RS, Brasil / Universidade Federal do Rio Grande do Sul. Departamento de Zoologia. Programa de Pós-Graduação em Biologia Animal. Porto Alegre, RS, Brasil.
publishDate 2012
dc.date.issued.fl_str_mv 2012
dc.date.accessioned.fl_str_mv 2018-09-24T18:06:10Z
dc.date.available.fl_str_mv 2018-09-24T18:06:10Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv DEPRÁ, Maríndia et al. Mar, a MITE family of hAT transposons in Drosophila. Mobile DNA, v. 3, n. 13, p. 1-12, 2012.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/29017
dc.identifier.issn.pt_BR.fl_str_mv 1759-8753
dc.identifier.doi.none.fl_str_mv 10.1186/1759-8753-3-13
dc.identifier.eissn.none.fl_str_mv 1759-8753
identifier_str_mv DEPRÁ, Maríndia et al. Mar, a MITE family of hAT transposons in Drosophila. Mobile DNA, v. 3, n. 13, p. 1-12, 2012.
1759-8753
10.1186/1759-8753-3-13
url https://www.arca.fiocruz.br/handle/icict/29017
dc.language.iso.fl_str_mv por
language por
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv BMC
publisher.none.fl_str_mv BMC
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
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https://www.arca.fiocruz.br/bitstream/icict/29017/2/MobileDNA8753-3-13.pdf
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