Leishmania infection in humans, dogs and sandflies in a visceral leishmaniasis endemic area in Maranhão, Brazil

Detalhes bibliográficos
Autor(a) principal: Felipe, Ilana Mirian Almeida
Data de Publicação: 2011
Outros Autores: Aquino, Dorlene Maria Cardoso de, Kuppinger, Oliver, Santos, Max Diego Cruz, Rangel, Maurício Eduardo Salgado, Barbosa, David Soeiro, Barral, Aldina Maria Prado, Werneck, Guilherme Loureiro, Caldas, Arlene de Jesus Mendes
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/6048
Resumo: Universidade Federal do Maranhão. São Luis, MA, Brasil
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spelling Felipe, Ilana Mirian AlmeidaAquino, Dorlene Maria Cardoso deKuppinger, OliverSantos, Max Diego CruzRangel, Maurício Eduardo SalgadoBarbosa, David SoeiroBarral, Aldina Maria PradoWerneck, Guilherme LoureiroCaldas, Arlene de Jesus Mendes2012-12-20T18:57:29Z2012-12-20T18:57:29Z2011FELIPE, I. M. A. et al. Leishmania infection in humans, dogs and sandflies in a visceral leishmaniasis endemic area in Maranhão, Brazil. Memórias do Instituto Oswaldo Cruz, v. 106, n. 2, p. 207-211, mar. 2011.0074-0276https://www.arca.fiocruz.br/handle/icict/6048engLeishmania infection in humans, dogs and sandflies in a visceral leishmaniasis endemic area in Maranhão, Brazilinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidade Federal do Maranhão. São Luis, MA, BrasilUniversidade Federal do Maranhão. São Luis, MA, BrasilUniversidade Federal do Maranhão. São Luis, MA, BrasilUniversidade Federal do Maranhão. São Luis, MA, BrasilUniversidade Federal do Maranhão. São Luis, MA, BrasilFundação Oswaldo Cruz. Escola Nacional de Saúde Pública. Rio de Janeiro, RJ, BrasilFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, BrasilFundação Oswaldo Cruz. Escola Nacional de Saúde Pública. Rio de Janeiro, RJ, BrasilUniversidade Federal do Maranhão. São Luis, MA, BrasilLeishmania infection in humans, dogs and sandflies was examined in the endemic visceral leishmaniasis (VL) municipality of Raposa, state of Maranhão, Brazil. In this study, we examined Leishmania chagasi infection in the blood serum of both humans and Canis familiaris and the natural Leishmania sp. infection rate in the sandfly vector, Lutzomyia longipalpis. Enzyme-linked immunosorbent assay, indirect immunofluorescence reaction and polymerase chain reaction were performed to detect Leishmania infections in humans, dogs and sandflies, respectively. Overall, 186 out of 986 studied human beings were infected with L. chagasi parasites, representing an infection prevalence of 18.9%. An even higher infection rate was detected in dogs, where 66 (47.8%) out of 138 were infected. Among all Lu. longipalpis captured (n = 1,881), only 26.7% were females. The Leishmania infection frequency for the vector Lu. longipalpis was 1.56%. Remarkably, all infected sandflies were found in the peridomiciliary area. Furthermore, a high incidence of asymptomatic forms of VL in the human and canine populations was observed. The results of this study suggest autochthonous transmission of L. chagasi in this endemic area for visceral leishmaniasis because infection by Leishmania sp. was identified in all important elements of the transmission chain.Serum prevalenceLutzomyia longipalpisVisceral leishmaniasisMaranhãoBrazilDoenças do CãoDoenças EndêmicasInsetos VetoresLeishmaniose VisceralLeishmaniose Visceral/veterináriaPsychodidaeBrasilELISATécnica Indireta de Fluorescência para AnticorpoLeishmaniaLeishmaniose VisceralReação em Cadeia da PolimeraseEstações do AnoAnimaisCãesFemininoHumanosMasculinoResearch Support, Non-U.S. Gov'tinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZORIGINALFelipe, Ilana Mirian Almeida et al. Leishmania infection in humans....pdfFelipe, Ilana Mirian Almeida et al. 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dc.title.pt_BR.fl_str_mv Leishmania infection in humans, dogs and sandflies in a visceral leishmaniasis endemic area in Maranhão, Brazil
title Leishmania infection in humans, dogs and sandflies in a visceral leishmaniasis endemic area in Maranhão, Brazil
spellingShingle Leishmania infection in humans, dogs and sandflies in a visceral leishmaniasis endemic area in Maranhão, Brazil
Felipe, Ilana Mirian Almeida
Serum prevalence
Lutzomyia longipalpis
Visceral leishmaniasis
Maranhão
Brazil
Doenças do Cão
Doenças Endêmicas
Insetos Vetores
Leishmaniose Visceral
Leishmaniose Visceral/veterinária
Psychodidae
Brasil
ELISA
Técnica Indireta de Fluorescência para Anticorpo
Leishmania
Leishmaniose Visceral
Reação em Cadeia da Polimerase
Estações do Ano
Animais
Cães
Feminino
Humanos
Masculino
Research Support, Non-U.S. Gov't
title_short Leishmania infection in humans, dogs and sandflies in a visceral leishmaniasis endemic area in Maranhão, Brazil
title_full Leishmania infection in humans, dogs and sandflies in a visceral leishmaniasis endemic area in Maranhão, Brazil
title_fullStr Leishmania infection in humans, dogs and sandflies in a visceral leishmaniasis endemic area in Maranhão, Brazil
title_full_unstemmed Leishmania infection in humans, dogs and sandflies in a visceral leishmaniasis endemic area in Maranhão, Brazil
title_sort Leishmania infection in humans, dogs and sandflies in a visceral leishmaniasis endemic area in Maranhão, Brazil
author Felipe, Ilana Mirian Almeida
author_facet Felipe, Ilana Mirian Almeida
Aquino, Dorlene Maria Cardoso de
Kuppinger, Oliver
Santos, Max Diego Cruz
Rangel, Maurício Eduardo Salgado
Barbosa, David Soeiro
Barral, Aldina Maria Prado
Werneck, Guilherme Loureiro
Caldas, Arlene de Jesus Mendes
author_role author
author2 Aquino, Dorlene Maria Cardoso de
Kuppinger, Oliver
Santos, Max Diego Cruz
Rangel, Maurício Eduardo Salgado
Barbosa, David Soeiro
Barral, Aldina Maria Prado
Werneck, Guilherme Loureiro
Caldas, Arlene de Jesus Mendes
author2_role author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Felipe, Ilana Mirian Almeida
Aquino, Dorlene Maria Cardoso de
Kuppinger, Oliver
Santos, Max Diego Cruz
Rangel, Maurício Eduardo Salgado
Barbosa, David Soeiro
Barral, Aldina Maria Prado
Werneck, Guilherme Loureiro
Caldas, Arlene de Jesus Mendes
dc.subject.en.pt_BR.fl_str_mv Serum prevalence
Lutzomyia longipalpis
Visceral leishmaniasis
Maranhão
Brazil
topic Serum prevalence
Lutzomyia longipalpis
Visceral leishmaniasis
Maranhão
Brazil
Doenças do Cão
Doenças Endêmicas
Insetos Vetores
Leishmaniose Visceral
Leishmaniose Visceral/veterinária
Psychodidae
Brasil
ELISA
Técnica Indireta de Fluorescência para Anticorpo
Leishmania
Leishmaniose Visceral
Reação em Cadeia da Polimerase
Estações do Ano
Animais
Cães
Feminino
Humanos
Masculino
Research Support, Non-U.S. Gov't
dc.subject.decs.pt_BR.fl_str_mv Doenças do Cão
Doenças Endêmicas
Insetos Vetores
Leishmaniose Visceral
Leishmaniose Visceral/veterinária
Psychodidae
Brasil
ELISA
Técnica Indireta de Fluorescência para Anticorpo
Leishmania
Leishmaniose Visceral
Reação em Cadeia da Polimerase
Estações do Ano
Animais
Cães
Feminino
Humanos
Masculino
Research Support, Non-U.S. Gov't
description Universidade Federal do Maranhão. São Luis, MA, Brasil
publishDate 2011
dc.date.issued.fl_str_mv 2011
dc.date.accessioned.fl_str_mv 2012-12-20T18:57:29Z
dc.date.available.fl_str_mv 2012-12-20T18:57:29Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv FELIPE, I. M. A. et al. Leishmania infection in humans, dogs and sandflies in a visceral leishmaniasis endemic area in Maranhão, Brazil. Memórias do Instituto Oswaldo Cruz, v. 106, n. 2, p. 207-211, mar. 2011.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/6048
dc.identifier.issn.none.fl_str_mv 0074-0276
identifier_str_mv FELIPE, I. M. A. et al. Leishmania infection in humans, dogs and sandflies in a visceral leishmaniasis endemic area in Maranhão, Brazil. Memórias do Instituto Oswaldo Cruz, v. 106, n. 2, p. 207-211, mar. 2011.
0074-0276
url https://www.arca.fiocruz.br/handle/icict/6048
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
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