Study of acetylsalicylic acid adsorption using molecular sieves
Autor(a) principal: | |
---|---|
Data de Publicação: | 2015 |
Outros Autores: | , , , |
Título da fonte: | Biblioteca Digital de Teses e Dissertações da FEI |
Texto Completo: | https://repositorio.fei.edu.br/handle/FEI/1678 |
Resumo: | Molecular sieves can be used as a host matrix to encapsulate several drugs. Here, we studied the adsorption of acetylsalicylic acid (ASA) in HUS-Y, HZSM-5 and silicalite-1 zeolites, as well as in the mesoporous sieve Si-MCM-41, and compared their adsorption capacities. The materials used generally presented good performance for ASA adsorption. Among the zeolites studied, HZSM-5 adsorbed large amounts of drug than the others. The Si-MCM-41 samples synthesized with fumed silica presented better adsorption performance than those synthesized with tetraethyl orthosilicate. The best mesoporous sample for adsorption synthesized with fumed silica was chosen for the kinetic assay. The adsorption kinetics of ASA for this sample fitted well to a second-order model. The initial loading rate and diffusion coefficient for the ASA-mesoporous sieve system were 0.153% (mg ASA)/(mg solid/minute) and 5.02 × 10-17 m2/s, respectively. The materials were characterized by X-ray diffraction, scanning electron microscopy, transmission electron microscopy and nitrogen physisorption. |
id |
FEI_8341565c0c09a2d39e49fe3e9928c293 |
---|---|
oai_identifier_str |
oai:repositorio.fei.edu.br:FEI/1678 |
network_acronym_str |
FEI |
network_name_str |
Biblioteca Digital de Teses e Dissertações da FEI |
repository_id_str |
|
spelling |
Assumpcao G.Poco J.Fernandez-Felisbino R.Cardoso D.Gomes E.2019-08-20T00:12:01Z2019-08-20T00:12:01Z2015ASSUMPÇÃO, G. A.; POÇO, J. G. R.; FERNANDEZ-FELISBINO, R.; CARDOSO, D.; GOMES, E. L.. Study of Acetylsalicylic Acid Adsorption Using Molecular Sieves. Adsorption Science & Technology, v. 33, n. 2, p. 203-222, 2015.2048-4038https://repositorio.fei.edu.br/handle/FEI/167810.1260/0263-6174.33.2.203Molecular sieves can be used as a host matrix to encapsulate several drugs. Here, we studied the adsorption of acetylsalicylic acid (ASA) in HUS-Y, HZSM-5 and silicalite-1 zeolites, as well as in the mesoporous sieve Si-MCM-41, and compared their adsorption capacities. The materials used generally presented good performance for ASA adsorption. Among the zeolites studied, HZSM-5 adsorbed large amounts of drug than the others. The Si-MCM-41 samples synthesized with fumed silica presented better adsorption performance than those synthesized with tetraethyl orthosilicate. The best mesoporous sample for adsorption synthesized with fumed silica was chosen for the kinetic assay. The adsorption kinetics of ASA for this sample fitted well to a second-order model. The initial loading rate and diffusion coefficient for the ASA-mesoporous sieve system were 0.153% (mg ASA)/(mg solid/minute) and 5.02 × 10-17 m2/s, respectively. The materials were characterized by X-ray diffraction, scanning electron microscopy, transmission electron microscopy and nitrogen physisorption.332203221Adsorption Science and TechnologyStudy of acetylsalicylic acid adsorption using molecular sievesinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/conferenceObjectinfo:eu-repo/semantics/openAccessreponame:Biblioteca Digital de Teses e Dissertações da FEIinstname:Centro Universitário da Fundação Educacional Inaciana (FEI)instacron:FEI12-s2.0-84926476326Acetyl salicylic acidAcetylsalicylic acidsAdsorption capacitiesAdsorption kineticsAdsorption performanceNitrogen physisorptionSecond-order modelsTetra-ethyl-ortho-silicatehttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84926476326&origin=inward2022-06-01FEI/16782022-06-01 03:07:38.699Biblioteca Digital de Teses e Dissertaçõeshttp://sofia.fei.edu.br/pergamum/biblioteca/PRI |
dc.title.none.fl_str_mv |
Study of acetylsalicylic acid adsorption using molecular sieves |
title |
Study of acetylsalicylic acid adsorption using molecular sieves |
spellingShingle |
Study of acetylsalicylic acid adsorption using molecular sieves Assumpcao G. |
title_short |
Study of acetylsalicylic acid adsorption using molecular sieves |
title_full |
Study of acetylsalicylic acid adsorption using molecular sieves |
title_fullStr |
Study of acetylsalicylic acid adsorption using molecular sieves |
title_full_unstemmed |
Study of acetylsalicylic acid adsorption using molecular sieves |
title_sort |
Study of acetylsalicylic acid adsorption using molecular sieves |
author |
Assumpcao G. |
author_facet |
Assumpcao G. Poco J. Fernandez-Felisbino R. Cardoso D. Gomes E. |
author_role |
author |
author2 |
Poco J. Fernandez-Felisbino R. Cardoso D. Gomes E. |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Assumpcao G. Poco J. Fernandez-Felisbino R. Cardoso D. Gomes E. |
description |
Molecular sieves can be used as a host matrix to encapsulate several drugs. Here, we studied the adsorption of acetylsalicylic acid (ASA) in HUS-Y, HZSM-5 and silicalite-1 zeolites, as well as in the mesoporous sieve Si-MCM-41, and compared their adsorption capacities. The materials used generally presented good performance for ASA adsorption. Among the zeolites studied, HZSM-5 adsorbed large amounts of drug than the others. The Si-MCM-41 samples synthesized with fumed silica presented better adsorption performance than those synthesized with tetraethyl orthosilicate. The best mesoporous sample for adsorption synthesized with fumed silica was chosen for the kinetic assay. The adsorption kinetics of ASA for this sample fitted well to a second-order model. The initial loading rate and diffusion coefficient for the ASA-mesoporous sieve system were 0.153% (mg ASA)/(mg solid/minute) and 5.02 × 10-17 m2/s, respectively. The materials were characterized by X-ray diffraction, scanning electron microscopy, transmission electron microscopy and nitrogen physisorption. |
publishDate |
2015 |
dc.date.issued.fl_str_mv |
2015 |
dc.date.accessioned.fl_str_mv |
2019-08-20T00:12:01Z |
dc.date.available.fl_str_mv |
2019-08-20T00:12:01Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/conferenceObject |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
ASSUMPÇÃO, G. A.; POÇO, J. G. R.; FERNANDEZ-FELISBINO, R.; CARDOSO, D.; GOMES, E. L.. Study of Acetylsalicylic Acid Adsorption Using Molecular Sieves. Adsorption Science & Technology, v. 33, n. 2, p. 203-222, 2015. |
dc.identifier.uri.fl_str_mv |
https://repositorio.fei.edu.br/handle/FEI/1678 |
dc.identifier.issn.none.fl_str_mv |
2048-4038 |
dc.identifier.doi.none.fl_str_mv |
10.1260/0263-6174.33.2.203 |
identifier_str_mv |
ASSUMPÇÃO, G. A.; POÇO, J. G. R.; FERNANDEZ-FELISBINO, R.; CARDOSO, D.; GOMES, E. L.. Study of Acetylsalicylic Acid Adsorption Using Molecular Sieves. Adsorption Science & Technology, v. 33, n. 2, p. 203-222, 2015. 2048-4038 10.1260/0263-6174.33.2.203 |
url |
https://repositorio.fei.edu.br/handle/FEI/1678 |
dc.relation.ispartof.none.fl_str_mv |
Adsorption Science and Technology |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.source.none.fl_str_mv |
reponame:Biblioteca Digital de Teses e Dissertações da FEI instname:Centro Universitário da Fundação Educacional Inaciana (FEI) instacron:FEI |
instname_str |
Centro Universitário da Fundação Educacional Inaciana (FEI) |
instacron_str |
FEI |
institution |
FEI |
reponame_str |
Biblioteca Digital de Teses e Dissertações da FEI |
collection |
Biblioteca Digital de Teses e Dissertações da FEI |
repository.name.fl_str_mv |
|
repository.mail.fl_str_mv |
|
_version_ |
1734750995508887552 |