Characterization of phenolic compounds, toxicity assessment, and quality analysis of tea samples from Miconia albicans

• Autor(a) principal: Hamann, Bruna
• Data de Publicação: 2020
• Outros Autores: Winter, Elisa Mara dos Santos, Silbert, Diogo Alexandre, Micke, Gustavo Amadeu, Vitali, Luciano, Tenfen, Adrielli, Zimmermann, Lara Almida
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Revista Fitos
• Texto Completo: https://revistafitos.far.fiocruz.br/index.php/revista-fitos/article/view/1055
• topic: Phytochemical analysis.; Tea; Artemia salina; Chromatography; Análise fitoquímica; Chá; Artemia salina; Cromatografia

The use of medicinal plants as a therapeutic alternative is growing in society. The species Miconia albicans, popularly known as old cinnamon, is being consumed in several regions of the country, as it has anti-inflammatory action. This work evaluated the volatile constituents and the quality of five samples of M. albicans teas, acquired in commercial environments in the city of Jaraguá do Sul. The information on their labels were compared and the presence of foreign matter, microorganisms, moisture content, and total ash were determined. The characterization of phenolic compounds in the samples was performed using HPLC-LC-ESI-MS / MS. Toxicity was assessed with Artemia salina larvae. Some samples showed irregularities regarding the specifications of packaging labels. The results of quality control of the vegetable raw material have shown to be in accordance with the specifications described in the Brazilian Pharmacopeia. The phenolic compounds analysis of five samples, as well as the phytochemical profile consistent with the species under study. The analyzed samples are potentially cytotoxic, which makes the species promising for future studies in the cancer’s treatment.