Action of Trypanosoma rangeli in infections with virulent Trypanosoma cruzi populations

Detalhes bibliográficos
Autor(a) principal: Paláu,MT
Data de Publicação: 2003
Outros Autores: Mejía,AJ, Vergara,U, Zúñiga,CA
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Memórias do Instituto Oswaldo Cruz
Texto Completo: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762003000400022
Resumo: In experimental murine infections with Trypanosoma rangeli it has been observed development immune response to Trypanosoma cruzi. The aim of the present work was to analyze the result of antigenic stimuli and the protective effect with T. rangeli in T. cruzi infections. Mice groups immunized with metacyclic trypomastigotes of T. rangeli (Choachí-2V strain), derived from haemolymph and salivary gland and reinfected with T. cruzi virulent populations (Tulahuen strain, SA strain and Dm28c clone) from infected in vitro cells, showed decrease severity of disease outcomes, low parasitemia levels and 100% survival of all mice immunized, in comparison with groups infected only with T. cruzi populations, which demonstrated tissue affection, high parasitemia levels and the death of all animals. The above mentioned data contribute to understand the biological behaviour of T. cruzi and T. rangeli and their interaction with vertebrate host.
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spelling Action of Trypanosoma rangeli in infections with virulent Trypanosoma cruzi populationsTrypanosoma cruziTrypanosoma rangeliprotective effectChagas diseaseparasitemia levelIn experimental murine infections with Trypanosoma rangeli it has been observed development immune response to Trypanosoma cruzi. The aim of the present work was to analyze the result of antigenic stimuli and the protective effect with T. rangeli in T. cruzi infections. Mice groups immunized with metacyclic trypomastigotes of T. rangeli (Choachí-2V strain), derived from haemolymph and salivary gland and reinfected with T. cruzi virulent populations (Tulahuen strain, SA strain and Dm28c clone) from infected in vitro cells, showed decrease severity of disease outcomes, low parasitemia levels and 100% survival of all mice immunized, in comparison with groups infected only with T. cruzi populations, which demonstrated tissue affection, high parasitemia levels and the death of all animals. The above mentioned data contribute to understand the biological behaviour of T. cruzi and T. rangeli and their interaction with vertebrate host.Instituto Oswaldo Cruz, Ministério da Saúde2003-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762003000400022Memórias do Instituto Oswaldo Cruz v.98 n.4 2003reponame:Memórias do Instituto Oswaldo Cruzinstname:Fundação Oswaldo Cruzinstacron:FIOCRUZ10.1590/S0074-02762003000400022info:eu-repo/semantics/openAccessPaláu,MTMejía,AJVergara,UZúñiga,CAeng2020-04-25T17:49:05Zhttp://www.scielo.br/oai/scielo-oai.php0074-02761678-8060opendoar:null2020-04-26 02:12:00.688Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruztrue
dc.title.none.fl_str_mv Action of Trypanosoma rangeli in infections with virulent Trypanosoma cruzi populations
title Action of Trypanosoma rangeli in infections with virulent Trypanosoma cruzi populations
spellingShingle Action of Trypanosoma rangeli in infections with virulent Trypanosoma cruzi populations
Paláu,MT
Trypanosoma cruzi
Trypanosoma rangeli
protective effect
Chagas disease
parasitemia level
title_short Action of Trypanosoma rangeli in infections with virulent Trypanosoma cruzi populations
title_full Action of Trypanosoma rangeli in infections with virulent Trypanosoma cruzi populations
title_fullStr Action of Trypanosoma rangeli in infections with virulent Trypanosoma cruzi populations
title_full_unstemmed Action of Trypanosoma rangeli in infections with virulent Trypanosoma cruzi populations
title_sort Action of Trypanosoma rangeli in infections with virulent Trypanosoma cruzi populations
author Paláu,MT
author_facet Paláu,MT
Mejía,AJ
Vergara,U
Zúñiga,CA
author_role author
author2 Mejía,AJ
Vergara,U
Zúñiga,CA
author2_role author
author
author
dc.contributor.author.fl_str_mv Paláu,MT
Mejía,AJ
Vergara,U
Zúñiga,CA
dc.subject.por.fl_str_mv Trypanosoma cruzi
Trypanosoma rangeli
protective effect
Chagas disease
parasitemia level
topic Trypanosoma cruzi
Trypanosoma rangeli
protective effect
Chagas disease
parasitemia level
dc.description.none.fl_txt_mv In experimental murine infections with Trypanosoma rangeli it has been observed development immune response to Trypanosoma cruzi. The aim of the present work was to analyze the result of antigenic stimuli and the protective effect with T. rangeli in T. cruzi infections. Mice groups immunized with metacyclic trypomastigotes of T. rangeli (Choachí-2V strain), derived from haemolymph and salivary gland and reinfected with T. cruzi virulent populations (Tulahuen strain, SA strain and Dm28c clone) from infected in vitro cells, showed decrease severity of disease outcomes, low parasitemia levels and 100% survival of all mice immunized, in comparison with groups infected only with T. cruzi populations, which demonstrated tissue affection, high parasitemia levels and the death of all animals. The above mentioned data contribute to understand the biological behaviour of T. cruzi and T. rangeli and their interaction with vertebrate host.
description In experimental murine infections with Trypanosoma rangeli it has been observed development immune response to Trypanosoma cruzi. The aim of the present work was to analyze the result of antigenic stimuli and the protective effect with T. rangeli in T. cruzi infections. Mice groups immunized with metacyclic trypomastigotes of T. rangeli (Choachí-2V strain), derived from haemolymph and salivary gland and reinfected with T. cruzi virulent populations (Tulahuen strain, SA strain and Dm28c clone) from infected in vitro cells, showed decrease severity of disease outcomes, low parasitemia levels and 100% survival of all mice immunized, in comparison with groups infected only with T. cruzi populations, which demonstrated tissue affection, high parasitemia levels and the death of all animals. The above mentioned data contribute to understand the biological behaviour of T. cruzi and T. rangeli and their interaction with vertebrate host.
publishDate 2003
dc.date.none.fl_str_mv 2003-06-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762003000400022
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762003000400022
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0074-02762003000400022
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Instituto Oswaldo Cruz, Ministério da Saúde
publisher.none.fl_str_mv Instituto Oswaldo Cruz, Ministério da Saúde
dc.source.none.fl_str_mv Memórias do Instituto Oswaldo Cruz v.98 n.4 2003
reponame:Memórias do Instituto Oswaldo Cruz
instname:Fundação Oswaldo Cruz
instacron:FIOCRUZ
reponame_str Memórias do Instituto Oswaldo Cruz
collection Memórias do Instituto Oswaldo Cruz
instname_str Fundação Oswaldo Cruz
instacron_str FIOCRUZ
institution FIOCRUZ
repository.name.fl_str_mv Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruz
repository.mail.fl_str_mv
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