The Plasmodium bottleneck: malaria parasite losses in the mosquito vector

Detalhes bibliográficos
Autor(a) principal: Smith,Ryan C
Data de Publicação: 2014
Outros Autores: Vega-Rodríguez,Joel, Jacobs-Lorena,Marcelo
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Memórias do Instituto Oswaldo Cruz
Texto Completo: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762014000500644
Resumo: Nearly one million people are killed every year by the malaria parasite Plasmodium. Although the disease-causing forms of the parasite exist only in the human blood, mosquitoes of the genus Anopheles are the obligate vector for transmission. Here, we review the parasite life cycle in the vector and highlight the human and mosquito contributions that limit malaria parasite development in the mosquito host. We address parasite killing in its mosquito host and bottlenecks in parasite numbers that might guide intervention strategies to prevent transmission.
id FIOCRUZ-4_f004bb99a3e5650b9501e76c96a7f888
oai_identifier_str oai:scielo:S0074-02762014000500644
network_acronym_str FIOCRUZ-4
network_name_str Memórias do Instituto Oswaldo Cruz
spelling The Plasmodium bottleneck: malaria parasite losses in the mosquito vectormalariamosquitoPlasmodiuminnateimmunityNearly one million people are killed every year by the malaria parasite Plasmodium. Although the disease-causing forms of the parasite exist only in the human blood, mosquitoes of the genus Anopheles are the obligate vector for transmission. Here, we review the parasite life cycle in the vector and highlight the human and mosquito contributions that limit malaria parasite development in the mosquito host. We address parasite killing in its mosquito host and bottlenecks in parasite numbers that might guide intervention strategies to prevent transmission.Instituto Oswaldo Cruz, Ministério da Saúde2014-08-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762014000500644Memórias do Instituto Oswaldo Cruz v.109 n.5 2014reponame:Memórias do Instituto Oswaldo Cruzinstname:Fundação Oswaldo Cruzinstacron:FIOCRUZ10.1590/0074-0276130597info:eu-repo/semantics/openAccessSmith,Ryan CVega-Rodríguez,JoelJacobs-Lorena,Marceloeng2020-04-25T17:51:46Zhttp://www.scielo.br/oai/scielo-oai.php0074-02761678-8060opendoar:null2020-04-26 02:19:45.824Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruztrue
dc.title.none.fl_str_mv The Plasmodium bottleneck: malaria parasite losses in the mosquito vector
title The Plasmodium bottleneck: malaria parasite losses in the mosquito vector
spellingShingle The Plasmodium bottleneck: malaria parasite losses in the mosquito vector
Smith,Ryan C
malaria
mosquito
Plasmodium
innate
immunity
title_short The Plasmodium bottleneck: malaria parasite losses in the mosquito vector
title_full The Plasmodium bottleneck: malaria parasite losses in the mosquito vector
title_fullStr The Plasmodium bottleneck: malaria parasite losses in the mosquito vector
title_full_unstemmed The Plasmodium bottleneck: malaria parasite losses in the mosquito vector
title_sort The Plasmodium bottleneck: malaria parasite losses in the mosquito vector
author Smith,Ryan C
author_facet Smith,Ryan C
Vega-Rodríguez,Joel
Jacobs-Lorena,Marcelo
author_role author
author2 Vega-Rodríguez,Joel
Jacobs-Lorena,Marcelo
author2_role author
author
dc.contributor.author.fl_str_mv Smith,Ryan C
Vega-Rodríguez,Joel
Jacobs-Lorena,Marcelo
dc.subject.por.fl_str_mv malaria
mosquito
Plasmodium
innate
immunity
topic malaria
mosquito
Plasmodium
innate
immunity
dc.description.none.fl_txt_mv Nearly one million people are killed every year by the malaria parasite Plasmodium. Although the disease-causing forms of the parasite exist only in the human blood, mosquitoes of the genus Anopheles are the obligate vector for transmission. Here, we review the parasite life cycle in the vector and highlight the human and mosquito contributions that limit malaria parasite development in the mosquito host. We address parasite killing in its mosquito host and bottlenecks in parasite numbers that might guide intervention strategies to prevent transmission.
description Nearly one million people are killed every year by the malaria parasite Plasmodium. Although the disease-causing forms of the parasite exist only in the human blood, mosquitoes of the genus Anopheles are the obligate vector for transmission. Here, we review the parasite life cycle in the vector and highlight the human and mosquito contributions that limit malaria parasite development in the mosquito host. We address parasite killing in its mosquito host and bottlenecks in parasite numbers that might guide intervention strategies to prevent transmission.
publishDate 2014
dc.date.none.fl_str_mv 2014-08-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762014000500644
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762014000500644
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/0074-0276130597
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Instituto Oswaldo Cruz, Ministério da Saúde
publisher.none.fl_str_mv Instituto Oswaldo Cruz, Ministério da Saúde
dc.source.none.fl_str_mv Memórias do Instituto Oswaldo Cruz v.109 n.5 2014
reponame:Memórias do Instituto Oswaldo Cruz
instname:Fundação Oswaldo Cruz
instacron:FIOCRUZ
reponame_str Memórias do Instituto Oswaldo Cruz
collection Memórias do Instituto Oswaldo Cruz
instname_str Fundação Oswaldo Cruz
instacron_str FIOCRUZ
institution FIOCRUZ
repository.name.fl_str_mv Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruz
repository.mail.fl_str_mv
_version_ 1669937716074119168

Registros relacionados