Experimental infection of Rio Mamore hantavirus in Sigmodontinae rodents

Detalhes bibliográficos
Autor(a) principal: Souza,William Marciel de
Data de Publicação: 2016
Outros Autores: Machado,Alex Martins, Figueiredo,Luiz Tadeu Moraes
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Memórias do Instituto Oswaldo Cruz
Texto Completo: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762016000600399
Resumo: This study shows an experimental spillover infection of Sigmodontinae rodents with Rio Mamore hantavirus (RIOMV). Necromys lasiurus and Akodon sp were infected with 103 RNA copies of RIOMV by intraperitoneal administration. The viral genome was detected in heart, lung, and kidney tissues 18 days after infection (ai), and viral excretion in urine and faeces began at four and six ai, respectively. These results reveal that urine and faeces of infected rodents contain the virus for at least 18 days. It is possible that inhaled aerosols of these excreta could transmit hantavirus to humans and other animals.
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spelling Experimental infection of Rio Mamore hantavirus in Sigmodontinae rodentsexperimental infectionRio Mamore hantaviruswild Sigmodontinae rodentsThis study shows an experimental spillover infection of Sigmodontinae rodents with Rio Mamore hantavirus (RIOMV). Necromys lasiurus and Akodon sp were infected with 103 RNA copies of RIOMV by intraperitoneal administration. The viral genome was detected in heart, lung, and kidney tissues 18 days after infection (ai), and viral excretion in urine and faeces began at four and six ai, respectively. These results reveal that urine and faeces of infected rodents contain the virus for at least 18 days. It is possible that inhaled aerosols of these excreta could transmit hantavirus to humans and other animals.Instituto Oswaldo Cruz, Ministério da Saúde2016-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762016000600399Memórias do Instituto Oswaldo Cruz v.111 n.6 2016reponame:Memórias do Instituto Oswaldo Cruzinstname:Fundação Oswaldo Cruzinstacron:FIOCRUZ10.1590/0074-02760160021info:eu-repo/semantics/openAccessSouza,William Marciel deMachado,Alex MartinsFigueiredo,Luiz Tadeu Moraeseng2020-04-25T17:52:27Zhttp://www.scielo.br/oai/scielo-oai.php0074-02761678-8060opendoar:null2020-04-26 02:21:24.323Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruztrue
dc.title.none.fl_str_mv Experimental infection of Rio Mamore hantavirus in Sigmodontinae rodents
title Experimental infection of Rio Mamore hantavirus in Sigmodontinae rodents
spellingShingle Experimental infection of Rio Mamore hantavirus in Sigmodontinae rodents
Souza,William Marciel de
experimental infection
Rio Mamore hantavirus
wild Sigmodontinae rodents
title_short Experimental infection of Rio Mamore hantavirus in Sigmodontinae rodents
title_full Experimental infection of Rio Mamore hantavirus in Sigmodontinae rodents
title_fullStr Experimental infection of Rio Mamore hantavirus in Sigmodontinae rodents
title_full_unstemmed Experimental infection of Rio Mamore hantavirus in Sigmodontinae rodents
title_sort Experimental infection of Rio Mamore hantavirus in Sigmodontinae rodents
author Souza,William Marciel de
author_facet Souza,William Marciel de
Machado,Alex Martins
Figueiredo,Luiz Tadeu Moraes
author_role author
author2 Machado,Alex Martins
Figueiredo,Luiz Tadeu Moraes
author2_role author
author
dc.contributor.author.fl_str_mv Souza,William Marciel de
Machado,Alex Martins
Figueiredo,Luiz Tadeu Moraes
dc.subject.por.fl_str_mv experimental infection
Rio Mamore hantavirus
wild Sigmodontinae rodents
topic experimental infection
Rio Mamore hantavirus
wild Sigmodontinae rodents
dc.description.none.fl_txt_mv This study shows an experimental spillover infection of Sigmodontinae rodents with Rio Mamore hantavirus (RIOMV). Necromys lasiurus and Akodon sp were infected with 103 RNA copies of RIOMV by intraperitoneal administration. The viral genome was detected in heart, lung, and kidney tissues 18 days after infection (ai), and viral excretion in urine and faeces began at four and six ai, respectively. These results reveal that urine and faeces of infected rodents contain the virus for at least 18 days. It is possible that inhaled aerosols of these excreta could transmit hantavirus to humans and other animals.
description This study shows an experimental spillover infection of Sigmodontinae rodents with Rio Mamore hantavirus (RIOMV). Necromys lasiurus and Akodon sp were infected with 103 RNA copies of RIOMV by intraperitoneal administration. The viral genome was detected in heart, lung, and kidney tissues 18 days after infection (ai), and viral excretion in urine and faeces began at four and six ai, respectively. These results reveal that urine and faeces of infected rodents contain the virus for at least 18 days. It is possible that inhaled aerosols of these excreta could transmit hantavirus to humans and other animals.
publishDate 2016
dc.date.none.fl_str_mv 2016-06-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762016000600399
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762016000600399
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/0074-02760160021
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Instituto Oswaldo Cruz, Ministério da Saúde
publisher.none.fl_str_mv Instituto Oswaldo Cruz, Ministério da Saúde
dc.source.none.fl_str_mv Memórias do Instituto Oswaldo Cruz v.111 n.6 2016
reponame:Memórias do Instituto Oswaldo Cruz
instname:Fundação Oswaldo Cruz
instacron:FIOCRUZ
reponame_str Memórias do Instituto Oswaldo Cruz
collection Memórias do Instituto Oswaldo Cruz
instname_str Fundação Oswaldo Cruz
instacron_str FIOCRUZ
institution FIOCRUZ
repository.name.fl_str_mv Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruz
repository.mail.fl_str_mv
_version_ 1669937721345310720

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