Maternal smoking during pregnancy and birth defects in children: a systematic review with meta-analysis
Autor(a) principal: | |
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Data de Publicação: | 2014 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Cadernos de Saúde Pública |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-311X2014001202491 |
Resumo: | This systematic review aimed to investigate the association between maternal smoking during pregnancy and birth defects in children. We performed an electronic search of observational studies in the databases ovid MEDLINE (1950 to April 2010), LILACS and SciELO. We included 188 studies with a total of 13,564,914 participants (192,655 cases). Significant positive associations were found between maternal smoking and birth defects in the following body systems: cardiovascular (OR: 1.11; 95%CI: 1.03-1.19), digestive (OR: 1.18; 95%CI: 1.07-1.30), musculoskeletal (OR: 1.27; 95%CI: 1.16-1.39) and face and neck (OR: 1.28; 95%CI: 1.19-1.37). The strength of association between maternal smoking and birth defects measured by the OR (95%CI) is significantly related to the amount of cigarettes smoked daily (χ2 = 12.1; df = 2; p = 0.002). In conclusion, maternal smoking during pregnancy is associated with congenital malformations in children and this association is dose-dependent. |
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Maternal smoking during pregnancy and birth defects in children: a systematic review with meta-analysisSmokingPregnancyCongenital AbnormalitiesThis systematic review aimed to investigate the association between maternal smoking during pregnancy and birth defects in children. We performed an electronic search of observational studies in the databases ovid MEDLINE (1950 to April 2010), LILACS and SciELO. We included 188 studies with a total of 13,564,914 participants (192,655 cases). Significant positive associations were found between maternal smoking and birth defects in the following body systems: cardiovascular (OR: 1.11; 95%CI: 1.03-1.19), digestive (OR: 1.18; 95%CI: 1.07-1.30), musculoskeletal (OR: 1.27; 95%CI: 1.16-1.39) and face and neck (OR: 1.28; 95%CI: 1.19-1.37). The strength of association between maternal smoking and birth defects measured by the OR (95%CI) is significantly related to the amount of cigarettes smoked daily (χ2 = 12.1; df = 2; p = 0.002). In conclusion, maternal smoking during pregnancy is associated with congenital malformations in children and this association is dose-dependent.Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz2014-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-311X2014001202491Cadernos de Saúde Pública v.30 n.12 2014reponame:Cadernos de Saúde Públicainstname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZ10.1590/0102-311x00115813info:eu-repo/semantics/openAccessNicoletti,DilvaniaAppel,Leilane DroppaSiedersberger Neto,PedroGuimarães,Gabriel WaihrichZhang,Linjieeng2018-08-01T00:00:00Zoai:scielo:S0102-311X2014001202491Revistahttp://cadernos.ensp.fiocruz.br/csp/https://old.scielo.br/oai/scielo-oai.phpcadernos@ensp.fiocruz.br||cadernos@ensp.fiocruz.br1678-44640102-311Xopendoar:2018-08-01T00:00Cadernos de Saúde Pública - Fundação Oswaldo Cruz (FIOCRUZ)false |
dc.title.none.fl_str_mv |
Maternal smoking during pregnancy and birth defects in children: a systematic review with meta-analysis |
title |
Maternal smoking during pregnancy and birth defects in children: a systematic review with meta-analysis |
spellingShingle |
Maternal smoking during pregnancy and birth defects in children: a systematic review with meta-analysis Nicoletti,Dilvania Smoking Pregnancy Congenital Abnormalities |
title_short |
Maternal smoking during pregnancy and birth defects in children: a systematic review with meta-analysis |
title_full |
Maternal smoking during pregnancy and birth defects in children: a systematic review with meta-analysis |
title_fullStr |
Maternal smoking during pregnancy and birth defects in children: a systematic review with meta-analysis |
title_full_unstemmed |
Maternal smoking during pregnancy and birth defects in children: a systematic review with meta-analysis |
title_sort |
Maternal smoking during pregnancy and birth defects in children: a systematic review with meta-analysis |
author |
Nicoletti,Dilvania |
author_facet |
Nicoletti,Dilvania Appel,Leilane Droppa Siedersberger Neto,Pedro Guimarães,Gabriel Waihrich Zhang,Linjie |
author_role |
author |
author2 |
Appel,Leilane Droppa Siedersberger Neto,Pedro Guimarães,Gabriel Waihrich Zhang,Linjie |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Nicoletti,Dilvania Appel,Leilane Droppa Siedersberger Neto,Pedro Guimarães,Gabriel Waihrich Zhang,Linjie |
dc.subject.por.fl_str_mv |
Smoking Pregnancy Congenital Abnormalities |
topic |
Smoking Pregnancy Congenital Abnormalities |
description |
This systematic review aimed to investigate the association between maternal smoking during pregnancy and birth defects in children. We performed an electronic search of observational studies in the databases ovid MEDLINE (1950 to April 2010), LILACS and SciELO. We included 188 studies with a total of 13,564,914 participants (192,655 cases). Significant positive associations were found between maternal smoking and birth defects in the following body systems: cardiovascular (OR: 1.11; 95%CI: 1.03-1.19), digestive (OR: 1.18; 95%CI: 1.07-1.30), musculoskeletal (OR: 1.27; 95%CI: 1.16-1.39) and face and neck (OR: 1.28; 95%CI: 1.19-1.37). The strength of association between maternal smoking and birth defects measured by the OR (95%CI) is significantly related to the amount of cigarettes smoked daily (χ2 = 12.1; df = 2; p = 0.002). In conclusion, maternal smoking during pregnancy is associated with congenital malformations in children and this association is dose-dependent. |
publishDate |
2014 |
dc.date.none.fl_str_mv |
2014-12-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-311X2014001202491 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-311X2014001202491 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/0102-311x00115813 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz |
publisher.none.fl_str_mv |
Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz |
dc.source.none.fl_str_mv |
Cadernos de Saúde Pública v.30 n.12 2014 reponame:Cadernos de Saúde Pública instname:Fundação Oswaldo Cruz (FIOCRUZ) instacron:FIOCRUZ |
instname_str |
Fundação Oswaldo Cruz (FIOCRUZ) |
instacron_str |
FIOCRUZ |
institution |
FIOCRUZ |
reponame_str |
Cadernos de Saúde Pública |
collection |
Cadernos de Saúde Pública |
repository.name.fl_str_mv |
Cadernos de Saúde Pública - Fundação Oswaldo Cruz (FIOCRUZ) |
repository.mail.fl_str_mv |
cadernos@ensp.fiocruz.br||cadernos@ensp.fiocruz.br |
_version_ |
1754115735032954881 |