HIV-1 seroprevalence in the general population of Salvador, Bahia State, Northeast Brazil
Autor(a) principal: | |
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Data de Publicação: | 2007 |
Outros Autores: | , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Cadernos de Saúde Pública |
Texto Completo: | https://cadernos.ensp.fiocruz.br/ojs/index.php/csp/article/view/3429 |
Resumo: | To estimate HIV-1 seroprevalence in the general population of Salvador, Bahia, Brazil, we conducted a cross-sectional survey of 3,437 residents from 1998 to 2000. Subjects were drawn from 30 sentinel areas representing a wide range of living conditions. Plasma samples were screened for HIV-1 antibodies by ELISA and confirmed by immunofluorescent assay. Subtype determination by HMA was performed after proviral DNA amplification. Phylogenetic analysis using parsimony was performed with the neighbor-joining method. Overall HIV-1 seroprevalence was 0.55% (19/3,446): 0.8% for men and 0.36% for women. Seroprevalence was higher in the 31-45-year age group (1%) and among persons with family income less than twice the minimum wage (0.78%) as compared to 0.33% for the higher income group. Syphilis was detected in 37% of HIV seropositive individuals. Phylogenetic inferences identified 10 samples as subtype B in the env region and 2 samples with Benv/Fgag/Fpol and Fenv/Bgag. Age > 30 years, male gender, and income < 2 times the minimum wage were identified as risk factors for HIV-1 infection. Extrapolating the proportion of seropositive individuals to Salvador, the number of HIV-1 infected individuals was estimated at 13,750. |
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HIV-1 seroprevalence in the general population of Salvador, Bahia State, Northeast BrazilHIV-1HIV SeroprevalenceCross-sectional StudiesTo estimate HIV-1 seroprevalence in the general population of Salvador, Bahia, Brazil, we conducted a cross-sectional survey of 3,437 residents from 1998 to 2000. Subjects were drawn from 30 sentinel areas representing a wide range of living conditions. Plasma samples were screened for HIV-1 antibodies by ELISA and confirmed by immunofluorescent assay. Subtype determination by HMA was performed after proviral DNA amplification. Phylogenetic analysis using parsimony was performed with the neighbor-joining method. Overall HIV-1 seroprevalence was 0.55% (19/3,446): 0.8% for men and 0.36% for women. Seroprevalence was higher in the 31-45-year age group (1%) and among persons with family income less than twice the minimum wage (0.78%) as compared to 0.33% for the higher income group. Syphilis was detected in 37% of HIV seropositive individuals. Phylogenetic inferences identified 10 samples as subtype B in the env region and 2 samples with Benv/Fgag/Fpol and Fenv/Bgag. Age > 30 years, male gender, and income < 2 times the minimum wage were identified as risk factors for HIV-1 infection. Extrapolating the proportion of seropositive individuals to Salvador, the number of HIV-1 infected individuals was estimated at 13,750.A seroprevalência do HIV-1 na população geral de Salvador, Bahia, Brasil, foi estimada em estudo de corte transversal com 3.437 indivíduos entre 1998-2000, residentes de 30 áreas sentinelas com ampla va-riedade de condições de vida. Realizou-se uma triagem para anticorpos anti-HIV-1 por ELISA e confirmados por imunofluorescência. A determinação do subtipo foi realizada por HMA, após amplificação do DNA proviral. As análises filogenéticas foram realizadas com PAUP utilizando os algoritmos neighbor-joining. A seroprevalência do HIV-1 foi de 0,55% (19/3.446): 0,8% para os homens e 0,36% para as mulheres. A seroprevalência foi mais alta no grupo de 31-45 anos (1%) e entre as pessoas com renda familiar inferior a dois salários mínimos (0,78%). A sífilis foi diagnosticada em 37% dos participantes HIV soropositivos. A análise filogenética identificou 10 amostras como subtipo B na região env, e duas amostras Benv/Fgag/Fpol e Fenv/Bgag. Idade > 30 anos, sexo masculino, renda < 2 salários mínimos se comportaram como fatores de riscos para a infecção por HIV-1. Se extrapolarmos a proporção de soropositivos para Salvador, o número de infectados pelo HIV seria 13.750.Reports in Public HealthCadernos de Saúde Pública2007-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlapplication/pdfhttps://cadernos.ensp.fiocruz.br/ojs/index.php/csp/article/view/3429Reports in Public Health; Vol. 23 No. 1 (2007): JanuaryCadernos de Saúde Pública; v. 23 n. 1 (2007): Janeiro1678-44640102-311Xreponame:Cadernos de Saúde Públicainstname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZenghttps://cadernos.ensp.fiocruz.br/ojs/index.php/csp/article/view/3429/6937https://cadernos.ensp.fiocruz.br/ojs/index.php/csp/article/view/3429/6938Dourado, InêsMilroy, Craig A.Mello, Marco Antônio GomesFerraro, Geraldo ArgoloCastro-Lima Filho, HumbertoGuimarães, Monick LindenmeyerMorgado, Mariza GonçalvesTeixeira, Maria GloriaBarreto, Maurício L.Galvão-Castro, Bernardoinfo:eu-repo/semantics/openAccess2024-03-06T15:27:36Zoai:ojs.teste-cadernos.ensp.fiocruz.br:article/3429Revistahttps://cadernos.ensp.fiocruz.br/ojs/index.php/csphttps://cadernos.ensp.fiocruz.br/ojs/index.php/csp/oaicadernos@ensp.fiocruz.br||cadernos@ensp.fiocruz.br1678-44640102-311Xopendoar:2024-03-06T13:03:58.046397Cadernos de Saúde Pública - Fundação Oswaldo Cruz (FIOCRUZ)true |
dc.title.none.fl_str_mv |
HIV-1 seroprevalence in the general population of Salvador, Bahia State, Northeast Brazil |
title |
HIV-1 seroprevalence in the general population of Salvador, Bahia State, Northeast Brazil |
spellingShingle |
HIV-1 seroprevalence in the general population of Salvador, Bahia State, Northeast Brazil Dourado, Inês HIV-1 HIV Seroprevalence Cross-sectional Studies |
title_short |
HIV-1 seroprevalence in the general population of Salvador, Bahia State, Northeast Brazil |
title_full |
HIV-1 seroprevalence in the general population of Salvador, Bahia State, Northeast Brazil |
title_fullStr |
HIV-1 seroprevalence in the general population of Salvador, Bahia State, Northeast Brazil |
title_full_unstemmed |
HIV-1 seroprevalence in the general population of Salvador, Bahia State, Northeast Brazil |
title_sort |
HIV-1 seroprevalence in the general population of Salvador, Bahia State, Northeast Brazil |
author |
Dourado, Inês |
author_facet |
Dourado, Inês Milroy, Craig A. Mello, Marco Antônio Gomes Ferraro, Geraldo Argolo Castro-Lima Filho, Humberto Guimarães, Monick Lindenmeyer Morgado, Mariza Gonçalves Teixeira, Maria Gloria Barreto, Maurício L. Galvão-Castro, Bernardo |
author_role |
author |
author2 |
Milroy, Craig A. Mello, Marco Antônio Gomes Ferraro, Geraldo Argolo Castro-Lima Filho, Humberto Guimarães, Monick Lindenmeyer Morgado, Mariza Gonçalves Teixeira, Maria Gloria Barreto, Maurício L. Galvão-Castro, Bernardo |
author2_role |
author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Dourado, Inês Milroy, Craig A. Mello, Marco Antônio Gomes Ferraro, Geraldo Argolo Castro-Lima Filho, Humberto Guimarães, Monick Lindenmeyer Morgado, Mariza Gonçalves Teixeira, Maria Gloria Barreto, Maurício L. Galvão-Castro, Bernardo |
dc.subject.por.fl_str_mv |
HIV-1 HIV Seroprevalence Cross-sectional Studies |
topic |
HIV-1 HIV Seroprevalence Cross-sectional Studies |
description |
To estimate HIV-1 seroprevalence in the general population of Salvador, Bahia, Brazil, we conducted a cross-sectional survey of 3,437 residents from 1998 to 2000. Subjects were drawn from 30 sentinel areas representing a wide range of living conditions. Plasma samples were screened for HIV-1 antibodies by ELISA and confirmed by immunofluorescent assay. Subtype determination by HMA was performed after proviral DNA amplification. Phylogenetic analysis using parsimony was performed with the neighbor-joining method. Overall HIV-1 seroprevalence was 0.55% (19/3,446): 0.8% for men and 0.36% for women. Seroprevalence was higher in the 31-45-year age group (1%) and among persons with family income less than twice the minimum wage (0.78%) as compared to 0.33% for the higher income group. Syphilis was detected in 37% of HIV seropositive individuals. Phylogenetic inferences identified 10 samples as subtype B in the env region and 2 samples with Benv/Fgag/Fpol and Fenv/Bgag. Age > 30 years, male gender, and income < 2 times the minimum wage were identified as risk factors for HIV-1 infection. Extrapolating the proportion of seropositive individuals to Salvador, the number of HIV-1 infected individuals was estimated at 13,750. |
publishDate |
2007 |
dc.date.none.fl_str_mv |
2007-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://cadernos.ensp.fiocruz.br/ojs/index.php/csp/article/view/3429 |
url |
https://cadernos.ensp.fiocruz.br/ojs/index.php/csp/article/view/3429 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://cadernos.ensp.fiocruz.br/ojs/index.php/csp/article/view/3429/6937 https://cadernos.ensp.fiocruz.br/ojs/index.php/csp/article/view/3429/6938 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html application/pdf |
dc.publisher.none.fl_str_mv |
Reports in Public Health Cadernos de Saúde Pública |
publisher.none.fl_str_mv |
Reports in Public Health Cadernos de Saúde Pública |
dc.source.none.fl_str_mv |
Reports in Public Health; Vol. 23 No. 1 (2007): January Cadernos de Saúde Pública; v. 23 n. 1 (2007): Janeiro 1678-4464 0102-311X reponame:Cadernos de Saúde Pública instname:Fundação Oswaldo Cruz (FIOCRUZ) instacron:FIOCRUZ |
instname_str |
Fundação Oswaldo Cruz (FIOCRUZ) |
instacron_str |
FIOCRUZ |
institution |
FIOCRUZ |
reponame_str |
Cadernos de Saúde Pública |
collection |
Cadernos de Saúde Pública |
repository.name.fl_str_mv |
Cadernos de Saúde Pública - Fundação Oswaldo Cruz (FIOCRUZ) |
repository.mail.fl_str_mv |
cadernos@ensp.fiocruz.br||cadernos@ensp.fiocruz.br |
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1798943361370947584 |