Decline in head circumference growth and associated factors in congenital Zika syndrome
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Cadernos de Saúde Pública |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-311X2022000805001 |
Resumo: | Little is known about the evolution of head circumference (HC) in children with congenital Zika syndrome (CZS). This study aims to evaluate HC growth in children with CZS in the first three years of life and identify associated factors. HC data obtained at birth and in neuropediatric consultations from 74 children with CZS were collected from the Child’s Health Handbook, parents’ reports, and medical records. Predictors of HC z-score were investigated using different mixed-effects models; Akaike’s information criterion was used for model selection. The HC z-score decreased from -2.7 ± 1.6 at birth to -5.5 ± 2.2 at 3 months of age, remaining relatively stable thereafter. In the selected adjusted model, the presence of severe brain parenchymal atrophy and maternal symptoms of infection in the first trimester of pregnancy were associated with a more pronounced reduction in the HC z-score in the first three years of life. The decrease of HC z-score in CZS children over the first three months demonstrated a reduced potential for growth and development of the central nervous system of these children. The prognosis of head growth in the first 3 years of life is worse when maternal infection occurs in the first gestational trimester and in children who have severe brain parenchymal atrophy. |
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Decline in head circumference growth and associated factors in congenital Zika syndromeZika VirusAnthropometryCephalometryGrowthStatistical ModelsLittle is known about the evolution of head circumference (HC) in children with congenital Zika syndrome (CZS). This study aims to evaluate HC growth in children with CZS in the first three years of life and identify associated factors. HC data obtained at birth and in neuropediatric consultations from 74 children with CZS were collected from the Child’s Health Handbook, parents’ reports, and medical records. Predictors of HC z-score were investigated using different mixed-effects models; Akaike’s information criterion was used for model selection. The HC z-score decreased from -2.7 ± 1.6 at birth to -5.5 ± 2.2 at 3 months of age, remaining relatively stable thereafter. In the selected adjusted model, the presence of severe brain parenchymal atrophy and maternal symptoms of infection in the first trimester of pregnancy were associated with a more pronounced reduction in the HC z-score in the first three years of life. The decrease of HC z-score in CZS children over the first three months demonstrated a reduced potential for growth and development of the central nervous system of these children. The prognosis of head growth in the first 3 years of life is worse when maternal infection occurs in the first gestational trimester and in children who have severe brain parenchymal atrophy.Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz2022-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-311X2022000805001Cadernos de Saúde Pública v.38 n.8 2022reponame:Cadernos de Saúde Públicainstname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZ10.1590/0102-311xen296021info:eu-repo/semantics/openAccessTakahasi,Eliana Harumi MoriokaAlves,Maria Teresa Seabra Soares de Britto eRibeiro,Marizélia Rodrigues CostaSantos,Alcione Miranda dosCampos,Marcos Adriano GarciaSimões,Vanda Maria FerreiraAmaral,Gláucio AndradeSousa,Patrícia da SilvaMiranda-Filho,Demócrito de BarrosSilva,Antônio Augusto Moura daeng2022-08-03T00:00:00Zoai:scielo:S0102-311X2022000805001Revistahttp://cadernos.ensp.fiocruz.br/csp/https://old.scielo.br/oai/scielo-oai.phpcadernos@ensp.fiocruz.br||cadernos@ensp.fiocruz.br1678-44640102-311Xopendoar:2022-08-03T00:00Cadernos de Saúde Pública - Fundação Oswaldo Cruz (FIOCRUZ)false |
dc.title.none.fl_str_mv |
Decline in head circumference growth and associated factors in congenital Zika syndrome |
title |
Decline in head circumference growth and associated factors in congenital Zika syndrome |
spellingShingle |
Decline in head circumference growth and associated factors in congenital Zika syndrome Takahasi,Eliana Harumi Morioka Zika Virus Anthropometry Cephalometry Growth Statistical Models |
title_short |
Decline in head circumference growth and associated factors in congenital Zika syndrome |
title_full |
Decline in head circumference growth and associated factors in congenital Zika syndrome |
title_fullStr |
Decline in head circumference growth and associated factors in congenital Zika syndrome |
title_full_unstemmed |
Decline in head circumference growth and associated factors in congenital Zika syndrome |
title_sort |
Decline in head circumference growth and associated factors in congenital Zika syndrome |
author |
Takahasi,Eliana Harumi Morioka |
author_facet |
Takahasi,Eliana Harumi Morioka Alves,Maria Teresa Seabra Soares de Britto e Ribeiro,Marizélia Rodrigues Costa Santos,Alcione Miranda dos Campos,Marcos Adriano Garcia Simões,Vanda Maria Ferreira Amaral,Gláucio Andrade Sousa,Patrícia da Silva Miranda-Filho,Demócrito de Barros Silva,Antônio Augusto Moura da |
author_role |
author |
author2 |
Alves,Maria Teresa Seabra Soares de Britto e Ribeiro,Marizélia Rodrigues Costa Santos,Alcione Miranda dos Campos,Marcos Adriano Garcia Simões,Vanda Maria Ferreira Amaral,Gláucio Andrade Sousa,Patrícia da Silva Miranda-Filho,Demócrito de Barros Silva,Antônio Augusto Moura da |
author2_role |
author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Takahasi,Eliana Harumi Morioka Alves,Maria Teresa Seabra Soares de Britto e Ribeiro,Marizélia Rodrigues Costa Santos,Alcione Miranda dos Campos,Marcos Adriano Garcia Simões,Vanda Maria Ferreira Amaral,Gláucio Andrade Sousa,Patrícia da Silva Miranda-Filho,Demócrito de Barros Silva,Antônio Augusto Moura da |
dc.subject.por.fl_str_mv |
Zika Virus Anthropometry Cephalometry Growth Statistical Models |
topic |
Zika Virus Anthropometry Cephalometry Growth Statistical Models |
description |
Little is known about the evolution of head circumference (HC) in children with congenital Zika syndrome (CZS). This study aims to evaluate HC growth in children with CZS in the first three years of life and identify associated factors. HC data obtained at birth and in neuropediatric consultations from 74 children with CZS were collected from the Child’s Health Handbook, parents’ reports, and medical records. Predictors of HC z-score were investigated using different mixed-effects models; Akaike’s information criterion was used for model selection. The HC z-score decreased from -2.7 ± 1.6 at birth to -5.5 ± 2.2 at 3 months of age, remaining relatively stable thereafter. In the selected adjusted model, the presence of severe brain parenchymal atrophy and maternal symptoms of infection in the first trimester of pregnancy were associated with a more pronounced reduction in the HC z-score in the first three years of life. The decrease of HC z-score in CZS children over the first three months demonstrated a reduced potential for growth and development of the central nervous system of these children. The prognosis of head growth in the first 3 years of life is worse when maternal infection occurs in the first gestational trimester and in children who have severe brain parenchymal atrophy. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-311X2022000805001 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-311X2022000805001 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/0102-311xen296021 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz |
publisher.none.fl_str_mv |
Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz |
dc.source.none.fl_str_mv |
Cadernos de Saúde Pública v.38 n.8 2022 reponame:Cadernos de Saúde Pública instname:Fundação Oswaldo Cruz (FIOCRUZ) instacron:FIOCRUZ |
instname_str |
Fundação Oswaldo Cruz (FIOCRUZ) |
instacron_str |
FIOCRUZ |
institution |
FIOCRUZ |
reponame_str |
Cadernos de Saúde Pública |
collection |
Cadernos de Saúde Pública |
repository.name.fl_str_mv |
Cadernos de Saúde Pública - Fundação Oswaldo Cruz (FIOCRUZ) |
repository.mail.fl_str_mv |
cadernos@ensp.fiocruz.br||cadernos@ensp.fiocruz.br |
_version_ |
1754115743524323328 |