Vulnerability and non-adherence to antiretroviral therapy among HIV patients, Minas Gerais State, Brazil
Autor(a) principal: | |
---|---|
Data de Publicação: | 2008 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Cadernos de Saúde Pública |
Texto Completo: | https://cadernos.ensp.fiocruz.br/ojs/index.php/csp/article/view/3665 |
Resumo: | The aim of the present study was to describe vulnerability profiles and to verify their association with non-adherence to antiretroviral therapy (ART) among 295 HIV-patients receiving their first prescription in two public-referral centers in Minas Gerais States, Brazil. The cumulative incidence of non-adherence was 36.9%. Three pure vulnerability profiles (lower, medium and higher) were identified based on the Grade of Membership method (GoM). Pure type patients of the "higher vulnerability" profile had, when compared to the overall sample, an increased probability of being younger, not understanding the need of ART, having a personal reason to be HIV-tested, not disclosing their HIV status, having more than one (non-regular) sexual partner, reporting use of alcohol, tobacco and illicit drugs, and having sex among men. Non-adherence to ART was statistically associated (p < 0.001) with this profile. Also, the heterogeneity of the sample was found to be high, since over 40% were mixed type. The implications are that health staff should be trained to develop strategies for incorporating risk-reduction interventions, bearing in mind the three dimensions of vulnerability and the diversity of those patients initiating antiretroviral therapy. |
id |
FIOCRUZ-5_630c424c23d17c008f0618d8eb5fcfb1 |
---|---|
oai_identifier_str |
oai:ojs.teste-cadernos.ensp.fiocruz.br:article/3665 |
network_acronym_str |
FIOCRUZ-5 |
network_name_str |
Cadernos de Saúde Pública |
repository_id_str |
|
spelling |
Vulnerability and non-adherence to antiretroviral therapy among HIV patients, Minas Gerais State, BrazilHIVHighly Active Antiretroviral TherapyVulnerabilityThe aim of the present study was to describe vulnerability profiles and to verify their association with non-adherence to antiretroviral therapy (ART) among 295 HIV-patients receiving their first prescription in two public-referral centers in Minas Gerais States, Brazil. The cumulative incidence of non-adherence was 36.9%. Three pure vulnerability profiles (lower, medium and higher) were identified based on the Grade of Membership method (GoM). Pure type patients of the "higher vulnerability" profile had, when compared to the overall sample, an increased probability of being younger, not understanding the need of ART, having a personal reason to be HIV-tested, not disclosing their HIV status, having more than one (non-regular) sexual partner, reporting use of alcohol, tobacco and illicit drugs, and having sex among men. Non-adherence to ART was statistically associated (p < 0.001) with this profile. Also, the heterogeneity of the sample was found to be high, since over 40% were mixed type. The implications are that health staff should be trained to develop strategies for incorporating risk-reduction interventions, bearing in mind the three dimensions of vulnerability and the diversity of those patients initiating antiretroviral therapy.Este estudo teve como objetivos descrever os perfis de vulnerabilidade e verificar suas associações com a não-adesão à terapia anti-retroviral (TARV) entre os 295 pacientes com HIV que recebiam suas primeiras prescrições em dois serviços públicos de referência de Minas Gerais, Brasil. A incidência cumulativa de não-adesão foi 36,9%. Foram identificados três perfis puros de vulnerabilidade (baixa, média e alta) baseados no método Grade of Membership (GoM). Os tipos puros de pacientes do perfil de "alta vulnerabilidade" tinham, comparados aos outros, probabilidade maior de serem jovens, de não perceberem a necessidade da TARV, de terem uma razão pessoal para realização do teste HIV, de não terem revelado seu status HIV, de terem mais de um (não fixo) parceiro sexual, de relatarem uso de álcool, tabaco e drogas ilícitas e sexo entre homens. Não-adesão à TARV foi associada significativamente a esse perfil (p < 0,001). A heterogeneidade da amostra foi alta, pois mais de 40% dos pacientes eram tipos mistos. Conclui-se que os profissionais de saúde devem ser treinados para desenvolverem estratégias e intervenções de redução de risco, considerando as três dimensões da vulnerabilidade e a diversidade desses pacientes iniciando a TARV.Reports in Public HealthCadernos de Saúde Pública2008-11-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlapplication/pdfhttps://cadernos.ensp.fiocruz.br/ojs/index.php/csp/article/view/3665Reports in Public Health; Vol. 24 No. 11 (2008): NovemberCadernos de Saúde Pública; v. 24 n. 11 (2008): Novembro1678-44640102-311Xreponame:Cadernos de Saúde Públicainstname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZenghttps://cadernos.ensp.fiocruz.br/ojs/index.php/csp/article/view/3665/7427https://cadernos.ensp.fiocruz.br/ojs/index.php/csp/article/view/3665/7428Bonolo, Palmira de FátimaMachado, Carla JorgeCésar, Cibele CominiCeccato, Maria das Graças BragaGuimarães, Mark Drew Croslandinfo:eu-repo/semantics/openAccess2024-03-06T15:27:44Zoai:ojs.teste-cadernos.ensp.fiocruz.br:article/3665Revistahttps://cadernos.ensp.fiocruz.br/ojs/index.php/csphttps://cadernos.ensp.fiocruz.br/ojs/index.php/csp/oaicadernos@ensp.fiocruz.br||cadernos@ensp.fiocruz.br1678-44640102-311Xopendoar:2024-03-06T13:04:12.695766Cadernos de Saúde Pública - Fundação Oswaldo Cruz (FIOCRUZ)true |
dc.title.none.fl_str_mv |
Vulnerability and non-adherence to antiretroviral therapy among HIV patients, Minas Gerais State, Brazil |
title |
Vulnerability and non-adherence to antiretroviral therapy among HIV patients, Minas Gerais State, Brazil |
spellingShingle |
Vulnerability and non-adherence to antiretroviral therapy among HIV patients, Minas Gerais State, Brazil Bonolo, Palmira de Fátima HIV Highly Active Antiretroviral Therapy Vulnerability |
title_short |
Vulnerability and non-adherence to antiretroviral therapy among HIV patients, Minas Gerais State, Brazil |
title_full |
Vulnerability and non-adherence to antiretroviral therapy among HIV patients, Minas Gerais State, Brazil |
title_fullStr |
Vulnerability and non-adherence to antiretroviral therapy among HIV patients, Minas Gerais State, Brazil |
title_full_unstemmed |
Vulnerability and non-adherence to antiretroviral therapy among HIV patients, Minas Gerais State, Brazil |
title_sort |
Vulnerability and non-adherence to antiretroviral therapy among HIV patients, Minas Gerais State, Brazil |
author |
Bonolo, Palmira de Fátima |
author_facet |
Bonolo, Palmira de Fátima Machado, Carla Jorge César, Cibele Comini Ceccato, Maria das Graças Braga Guimarães, Mark Drew Crosland |
author_role |
author |
author2 |
Machado, Carla Jorge César, Cibele Comini Ceccato, Maria das Graças Braga Guimarães, Mark Drew Crosland |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Bonolo, Palmira de Fátima Machado, Carla Jorge César, Cibele Comini Ceccato, Maria das Graças Braga Guimarães, Mark Drew Crosland |
dc.subject.por.fl_str_mv |
HIV Highly Active Antiretroviral Therapy Vulnerability |
topic |
HIV Highly Active Antiretroviral Therapy Vulnerability |
description |
The aim of the present study was to describe vulnerability profiles and to verify their association with non-adherence to antiretroviral therapy (ART) among 295 HIV-patients receiving their first prescription in two public-referral centers in Minas Gerais States, Brazil. The cumulative incidence of non-adherence was 36.9%. Three pure vulnerability profiles (lower, medium and higher) were identified based on the Grade of Membership method (GoM). Pure type patients of the "higher vulnerability" profile had, when compared to the overall sample, an increased probability of being younger, not understanding the need of ART, having a personal reason to be HIV-tested, not disclosing their HIV status, having more than one (non-regular) sexual partner, reporting use of alcohol, tobacco and illicit drugs, and having sex among men. Non-adherence to ART was statistically associated (p < 0.001) with this profile. Also, the heterogeneity of the sample was found to be high, since over 40% were mixed type. The implications are that health staff should be trained to develop strategies for incorporating risk-reduction interventions, bearing in mind the three dimensions of vulnerability and the diversity of those patients initiating antiretroviral therapy. |
publishDate |
2008 |
dc.date.none.fl_str_mv |
2008-11-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://cadernos.ensp.fiocruz.br/ojs/index.php/csp/article/view/3665 |
url |
https://cadernos.ensp.fiocruz.br/ojs/index.php/csp/article/view/3665 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://cadernos.ensp.fiocruz.br/ojs/index.php/csp/article/view/3665/7427 https://cadernos.ensp.fiocruz.br/ojs/index.php/csp/article/view/3665/7428 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html application/pdf |
dc.publisher.none.fl_str_mv |
Reports in Public Health Cadernos de Saúde Pública |
publisher.none.fl_str_mv |
Reports in Public Health Cadernos de Saúde Pública |
dc.source.none.fl_str_mv |
Reports in Public Health; Vol. 24 No. 11 (2008): November Cadernos de Saúde Pública; v. 24 n. 11 (2008): Novembro 1678-4464 0102-311X reponame:Cadernos de Saúde Pública instname:Fundação Oswaldo Cruz (FIOCRUZ) instacron:FIOCRUZ |
instname_str |
Fundação Oswaldo Cruz (FIOCRUZ) |
instacron_str |
FIOCRUZ |
institution |
FIOCRUZ |
reponame_str |
Cadernos de Saúde Pública |
collection |
Cadernos de Saúde Pública |
repository.name.fl_str_mv |
Cadernos de Saúde Pública - Fundação Oswaldo Cruz (FIOCRUZ) |
repository.mail.fl_str_mv |
cadernos@ensp.fiocruz.br||cadernos@ensp.fiocruz.br |
_version_ |
1798943362788622336 |