Trajectories of cognitive decline over 10 years in a Brazilian elderly population: the Bambuí cohort study of aging

• Autor(a) principal: Castro-Costa, Erico
• Data de Publicação: 2011
• Outros Autores: Dewey, Michael E., Uchôa, Elizabeth, Firmo, Josélia O. A., Lima-Costa, Maria Fernanda, Stewart, Robert
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Cadernos de Saúde Pública
• Texto Completo: https://cadernos.ensp.fiocruz.br/ojs/index.php/csp/article/view/4674
• topic: Cognition; Mental Health; Aged; Cohort Studies

Few population-based studies have examined long term cognitive trajectory, and these studies were conducted in high income countries. We investigated the association of age, gender and education with 10-year cognitive trajectory in a well-defined population of elderly using data from the Bambuí Cohort Study of Aging, in Brazil. Cognition was measured using the Mini- Mental State Examination (MMSE). Cohort members underwent annual follow-ups. This analysis was based on 12,206 MMSE measurements from 1,461 (91%) baseline participants. We used mixed effects models to study MMSE as outcome. The key findings from this analysis are that women and people with a higher schooling level at baseline had high scores of MMSE, while older participants started off lower. Regarding cognitive decline, women, older people and those with a higher schooling level declined faster.