Filariose linfática: doença potencialmente eliminável
Autor(a) principal: | |
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Data de Publicação: | 1997 |
Outros Autores: | |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Cadernos de Saúde Pública |
Texto Completo: | https://cadernos.ensp.fiocruz.br/ojs/index.php/csp/article/view/891 |
Resumo: | The recent demonstration that single-dose ivermectin, diethylcarbamazine, or a combination of these drugs can profoundly suppress Wuchereria bancrofti and Brugia malayi microfilaremia for periods of six months to two years has led to renewed hope that transmission can be interrupted and lymphatic filariasis eradicated. Based in part on the availability of these new chemotherapeutic tools, the International Task Force for Disease Eradication recently identified lymphatic filariasis as one of the few diseases that could potentially be eradicated. Thus, control programs based on mass treatment (whether supplemented or not by vector control) have begun to be implemented in some endemic areas. We provide a brief review of available anti-filarial drugs for use in humans, including their tolerance and efficacy. |
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Filariose linfática: doença potencialmente eliminávelFilariose LinfáticaControleIvermectinaDietilcarbamazinaWuchereria bancroftiThe recent demonstration that single-dose ivermectin, diethylcarbamazine, or a combination of these drugs can profoundly suppress Wuchereria bancrofti and Brugia malayi microfilaremia for periods of six months to two years has led to renewed hope that transmission can be interrupted and lymphatic filariasis eradicated. Based in part on the availability of these new chemotherapeutic tools, the International Task Force for Disease Eradication recently identified lymphatic filariasis as one of the few diseases that could potentially be eradicated. Thus, control programs based on mass treatment (whether supplemented or not by vector control) have begun to be implemented in some endemic areas. We provide a brief review of available anti-filarial drugs for use in humans, including their tolerance and efficacy.Os resultados obtidos com o uso de esquemas terapêuticos simples, como dose única anual ou bianual de Ivermectina (IV), Dietilcarbamazina (DEC) sozinhas ou combinadas, têm sido surpreendentemente promissores na redução da infecção linfática causada pela Wuchereria bancrofti e Brugia malayi. Assim, perspectivas existem de eliminar a doença dos países endêmicos, se programas de controle forem empregados usando-se o tratamento em massa, complementado ou não pelo controle do vetor. Uma breve revisão é feita sobre cada droga em relação à eficácia e às reações adversas causadas pela morte dos diversos estágios do parasita no homem infectado.Reports in Public HealthCadernos de Saúde Pública1997-09-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlapplication/pdfhttps://cadernos.ensp.fiocruz.br/ojs/index.php/csp/article/view/891Reports in Public Health; Vol. 13 No. 3 (1997): July/SeptemberCadernos de Saúde Pública; v. 13 n. 3 (1997): Julho/Setembro1678-44640102-311Xreponame:Cadernos de Saúde Públicainstname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZporhttps://cadernos.ensp.fiocruz.br/ojs/index.php/csp/article/view/891/1772https://cadernos.ensp.fiocruz.br/ojs/index.php/csp/article/view/891/1773Dreyer, GerusaCoelho, Giovaniniinfo:eu-repo/semantics/openAccess2024-03-06T15:26:07Zoai:ojs.teste-cadernos.ensp.fiocruz.br:article/891Revistahttps://cadernos.ensp.fiocruz.br/ojs/index.php/csphttps://cadernos.ensp.fiocruz.br/ojs/index.php/csp/oaicadernos@ensp.fiocruz.br||cadernos@ensp.fiocruz.br1678-44640102-311Xopendoar:2024-03-06T13:01:06.127790Cadernos de Saúde Pública - Fundação Oswaldo Cruz (FIOCRUZ)true |
dc.title.none.fl_str_mv |
Filariose linfática: doença potencialmente eliminável |
title |
Filariose linfática: doença potencialmente eliminável |
spellingShingle |
Filariose linfática: doença potencialmente eliminável Dreyer, Gerusa Filariose Linfática Controle Ivermectina Dietilcarbamazina Wuchereria bancrofti |
title_short |
Filariose linfática: doença potencialmente eliminável |
title_full |
Filariose linfática: doença potencialmente eliminável |
title_fullStr |
Filariose linfática: doença potencialmente eliminável |
title_full_unstemmed |
Filariose linfática: doença potencialmente eliminável |
title_sort |
Filariose linfática: doença potencialmente eliminável |
author |
Dreyer, Gerusa |
author_facet |
Dreyer, Gerusa Coelho, Giovanini |
author_role |
author |
author2 |
Coelho, Giovanini |
author2_role |
author |
dc.contributor.author.fl_str_mv |
Dreyer, Gerusa Coelho, Giovanini |
dc.subject.por.fl_str_mv |
Filariose Linfática Controle Ivermectina Dietilcarbamazina Wuchereria bancrofti |
topic |
Filariose Linfática Controle Ivermectina Dietilcarbamazina Wuchereria bancrofti |
description |
The recent demonstration that single-dose ivermectin, diethylcarbamazine, or a combination of these drugs can profoundly suppress Wuchereria bancrofti and Brugia malayi microfilaremia for periods of six months to two years has led to renewed hope that transmission can be interrupted and lymphatic filariasis eradicated. Based in part on the availability of these new chemotherapeutic tools, the International Task Force for Disease Eradication recently identified lymphatic filariasis as one of the few diseases that could potentially be eradicated. Thus, control programs based on mass treatment (whether supplemented or not by vector control) have begun to be implemented in some endemic areas. We provide a brief review of available anti-filarial drugs for use in humans, including their tolerance and efficacy. |
publishDate |
1997 |
dc.date.none.fl_str_mv |
1997-09-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://cadernos.ensp.fiocruz.br/ojs/index.php/csp/article/view/891 |
url |
https://cadernos.ensp.fiocruz.br/ojs/index.php/csp/article/view/891 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://cadernos.ensp.fiocruz.br/ojs/index.php/csp/article/view/891/1772 https://cadernos.ensp.fiocruz.br/ojs/index.php/csp/article/view/891/1773 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html application/pdf |
dc.publisher.none.fl_str_mv |
Reports in Public Health Cadernos de Saúde Pública |
publisher.none.fl_str_mv |
Reports in Public Health Cadernos de Saúde Pública |
dc.source.none.fl_str_mv |
Reports in Public Health; Vol. 13 No. 3 (1997): July/September Cadernos de Saúde Pública; v. 13 n. 3 (1997): Julho/Setembro 1678-4464 0102-311X reponame:Cadernos de Saúde Pública instname:Fundação Oswaldo Cruz (FIOCRUZ) instacron:FIOCRUZ |
instname_str |
Fundação Oswaldo Cruz (FIOCRUZ) |
instacron_str |
FIOCRUZ |
institution |
FIOCRUZ |
reponame_str |
Cadernos de Saúde Pública |
collection |
Cadernos de Saúde Pública |
repository.name.fl_str_mv |
Cadernos de Saúde Pública - Fundação Oswaldo Cruz (FIOCRUZ) |
repository.mail.fl_str_mv |
cadernos@ensp.fiocruz.br||cadernos@ensp.fiocruz.br |
_version_ |
1798943344268673024 |