Malignant and Premalignant Skin Lesions After Kidney Transplant: case report and literature review

• Autor(a) principal: de Almeida, Ana Paula Moura
• Data de Publicação: 2014
• Outros Autores: de Almeida, Liana Moura, Peçanha, Maria Auxiliadora Peixoto
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Revista Científica da Faculdade de Medicina de Campos
• Texto Completo: https://www.fmc.br/ojs/index.php/RCFMC/article/view/60

In its function of mediator between the organism and the environment, the skin, besides its barrier fuction, also presents immunological defense mecanisms. In kidney tranplants, these protection mecanisms are harmed by the use of immunosuppresives. Objective: Report a case of multiple squamous cell carcinomas and actinic keratoses, besides common warts and porokeratosis, in a eight year kidney transplanted patient. Description: Female patient, 49 years old, white, skin type II, countryside resident, kidney transplanted 15 years ago, presents multiples actinic keratosis especially in upper limbs and in the face. The patient initially used triple regimen of immunosuppression with Azathioprine 120mg/ day, Predinisone 20mg/day and Tacrolimus 5mg/twice a day. Approximately eight years after the transplant, multiple actinic keratosis appeared and there were diagnosed multiple carcinomas in photo-exposed areas. As a treatment conduct, it was scheduled a cryotherapy in order to treat the actinic keratosis, besides surgical removal of suspicious malignant lesions. Conclusions: It is extremely important the dermatological exam and the periodic monitoring in all the kidney transplanted patients, which allows the early diagnostic and treatment not only of nonmelanoma skin carcinomas, but also of multiple pre-malignant existing lesions.