Prevalence of herpes simplex virus type 2 and risk factors associated with this infection in women in southern Brazil
Autor(a) principal: | |
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Data de Publicação: | 2013 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Repositório Institucional da FURG (RI FURG) |
Texto Completo: | http://repositorio.furg.br/handle/1/6954 |
Resumo: | The herpes simplex virus type 2 (HVS-2) is the most prevalent infection worldwide. It is a cofactor in the acquisition of human immunodeficiency virus (HIV) and the persistence of human papillomavirus (HPV). This study evaluated the prevalence of HSV-2, using the polymerase chain reaction (PCR), and associated factors in patients treated at the Federal University of Rio Grande (FURG) and Basic Health Units (BHU) in Rio Grande, Brazil. The observed prevalence of HSV-2 was 15.6%. Among the 302 women studied, 158 had received assistance in BHU and 144 were treated at FURG. The prevalence of HSV-2 in these groups was 10.8% and 20.8%, respectively, RR 1.9 and p = 0.012. Knowledge about the Pap smear, and the presence of lesions showed no association with HSV-2 infection. Multivariate analysis showed that the variable that most influenced the risk of HSV-2 infection was the presence of HIV infection, with a relative risk of 1.9 and p = 0.04. Discussion: Genital ulcers are an important entry point for HIV, and condom use is an important strategy to reduce transmission of HIV and HSV-2. |
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Caldeira, Thaís Duquia MoraesGonçalves, Carla VitolaOliveira, Gisele Rodrigues deFonseca, Tania Maria Morais Vieira daGonçalves, Regina Maria CarvalhoAmaral, Clair Teixeira doHora, Vanusa Pousada daMartinez, Ana Maria Barral de2016-12-26T22:49:44Z2016-12-26T22:49:44Z2013CALDEIRA, Thaís Duquia Moraes; et al. Prevalence of herpes simplex virus type 2 and risk factors associated with this infection in women in southern Brazil. Revista do Instituto de Medicina Tropical de São Paulo. v. 55, n. 5, p. 315-321, 2013. Disponível em: <https: /Users/Cristina/Downloads/0036-4665-rimtsp-55-05-315.pdf> Acesso em 06 dec. 2016.http://repositorio.furg.br/handle/1/6954: 10.1590/S0036-46652013000500004The herpes simplex virus type 2 (HVS-2) is the most prevalent infection worldwide. It is a cofactor in the acquisition of human immunodeficiency virus (HIV) and the persistence of human papillomavirus (HPV). This study evaluated the prevalence of HSV-2, using the polymerase chain reaction (PCR), and associated factors in patients treated at the Federal University of Rio Grande (FURG) and Basic Health Units (BHU) in Rio Grande, Brazil. The observed prevalence of HSV-2 was 15.6%. Among the 302 women studied, 158 had received assistance in BHU and 144 were treated at FURG. The prevalence of HSV-2 in these groups was 10.8% and 20.8%, respectively, RR 1.9 and p = 0.012. Knowledge about the Pap smear, and the presence of lesions showed no association with HSV-2 infection. Multivariate analysis showed that the variable that most influenced the risk of HSV-2 infection was the presence of HIV infection, with a relative risk of 1.9 and p = 0.04. Discussion: Genital ulcers are an important entry point for HIV, and condom use is an important strategy to reduce transmission of HIV and HSV-2.O vírus herpes simplex tipo 2 (HVS-2) é uma das infecções mais prevalentes em todo o mundo. Considera-se um co-factor na aquisição do vírus da imunodeficiência humana (HIV) e na persistência do papilomavirus humano (HPV). Este estudo tem como objetivo avaliar a prevalência de HSV-2 usando a reação em cadeia da polimerase (PCR) e fatores associados em pacientes atendidos na Universidade Federal do Rio Grande e em Unidades Básicas de Saúde (UBS) do Rio Grande, Brasil. A prevalência de HSV-2 encontrada neste estudo foi de 15,6%. Entre as 302 mulheres estudadas, 158 haviam recebido assistência na UBS e 144 foram atendidos na FURG. A prevalência de HSV-2 nestes grupos foi de 10,8 e 20,8%, respectivamente, com RR: 1,9 e p = 0,012. Conhecer o exame de Papanicolaou, e presença de lesão não teve associação com infecção HSV-2. A análise multivariada mostrou que a variável que influencia no risco de infecção HSV-2 foi o paciente ter HIV, com risco relativo 1,9 e p = 0,04. Discussão: As úlceras genitais são importante porta de entrada para o vírus HIV e o uso do preservativo é estratégia importante para reduzir a transmissão do HIV e do HSV-2.porHuman herpesvirus 2Polymerase chain reactionHuman papillomavirusHIV infectionsPrevalence of herpes simplex virus type 2 and risk factors associated with this infection in women in southern BrazilPrevalência do herpes vírus tipo 2 e fatores de risco associados a sua infecção em mulheres do sul do Brasilinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FURG (RI FURG)instname:Universidade Federal do Rio Grande (FURG)instacron:FURGORIGINAL0036-4665-rimtsp-55-05-315.pdf0036-4665-rimtsp-55-05-315.pdfapplication/pdf648901https://repositorio.furg.br/bitstream/1/6954/1/0036-4665-rimtsp-55-05-315.pdf96266bd84229169422fcce65a1a1013dMD51open accessLICENSElicense.txtlicense.txttext/plain; charset=utf-81748https://repositorio.furg.br/bitstream/1/6954/2/license.txt8a4605be74aa9ea9d79846c1fba20a33MD52open access1/69542019-11-11 16:26:42.711open accessoai:repositorio.furg.br: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Repositório InstitucionalPUBhttps://repositorio.furg.br/oai/request || http://200.19.254.174/oai/requestopendoar:2019-11-11T19:26:42Repositório Institucional da FURG (RI FURG) - Universidade Federal do Rio Grande (FURG)false |
dc.title.pt_BR.fl_str_mv |
Prevalence of herpes simplex virus type 2 and risk factors associated with this infection in women in southern Brazil |
dc.title.alternative.pt_BR.fl_str_mv |
Prevalência do herpes vírus tipo 2 e fatores de risco associados a sua infecção em mulheres do sul do Brasil |
title |
Prevalence of herpes simplex virus type 2 and risk factors associated with this infection in women in southern Brazil |
spellingShingle |
Prevalence of herpes simplex virus type 2 and risk factors associated with this infection in women in southern Brazil Caldeira, Thaís Duquia Moraes Human herpesvirus 2 Polymerase chain reaction Human papillomavirus HIV infections |
title_short |
Prevalence of herpes simplex virus type 2 and risk factors associated with this infection in women in southern Brazil |
title_full |
Prevalence of herpes simplex virus type 2 and risk factors associated with this infection in women in southern Brazil |
title_fullStr |
Prevalence of herpes simplex virus type 2 and risk factors associated with this infection in women in southern Brazil |
title_full_unstemmed |
Prevalence of herpes simplex virus type 2 and risk factors associated with this infection in women in southern Brazil |
title_sort |
Prevalence of herpes simplex virus type 2 and risk factors associated with this infection in women in southern Brazil |
author |
Caldeira, Thaís Duquia Moraes |
author_facet |
Caldeira, Thaís Duquia Moraes Gonçalves, Carla Vitola Oliveira, Gisele Rodrigues de Fonseca, Tania Maria Morais Vieira da Gonçalves, Regina Maria Carvalho Amaral, Clair Teixeira do Hora, Vanusa Pousada da Martinez, Ana Maria Barral de |
author_role |
author |
author2 |
Gonçalves, Carla Vitola Oliveira, Gisele Rodrigues de Fonseca, Tania Maria Morais Vieira da Gonçalves, Regina Maria Carvalho Amaral, Clair Teixeira do Hora, Vanusa Pousada da Martinez, Ana Maria Barral de |
author2_role |
author author author author author author author |
dc.contributor.author.fl_str_mv |
Caldeira, Thaís Duquia Moraes Gonçalves, Carla Vitola Oliveira, Gisele Rodrigues de Fonseca, Tania Maria Morais Vieira da Gonçalves, Regina Maria Carvalho Amaral, Clair Teixeira do Hora, Vanusa Pousada da Martinez, Ana Maria Barral de |
dc.subject.por.fl_str_mv |
Human herpesvirus 2 Polymerase chain reaction Human papillomavirus HIV infections |
topic |
Human herpesvirus 2 Polymerase chain reaction Human papillomavirus HIV infections |
description |
The herpes simplex virus type 2 (HVS-2) is the most prevalent infection worldwide. It is a cofactor in the acquisition of human immunodeficiency virus (HIV) and the persistence of human papillomavirus (HPV). This study evaluated the prevalence of HSV-2, using the polymerase chain reaction (PCR), and associated factors in patients treated at the Federal University of Rio Grande (FURG) and Basic Health Units (BHU) in Rio Grande, Brazil. The observed prevalence of HSV-2 was 15.6%. Among the 302 women studied, 158 had received assistance in BHU and 144 were treated at FURG. The prevalence of HSV-2 in these groups was 10.8% and 20.8%, respectively, RR 1.9 and p = 0.012. Knowledge about the Pap smear, and the presence of lesions showed no association with HSV-2 infection. Multivariate analysis showed that the variable that most influenced the risk of HSV-2 infection was the presence of HIV infection, with a relative risk of 1.9 and p = 0.04. Discussion: Genital ulcers are an important entry point for HIV, and condom use is an important strategy to reduce transmission of HIV and HSV-2. |
publishDate |
2013 |
dc.date.issued.fl_str_mv |
2013 |
dc.date.accessioned.fl_str_mv |
2016-12-26T22:49:44Z |
dc.date.available.fl_str_mv |
2016-12-26T22:49:44Z |
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info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
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publishedVersion |
dc.identifier.citation.fl_str_mv |
CALDEIRA, Thaís Duquia Moraes; et al. Prevalence of herpes simplex virus type 2 and risk factors associated with this infection in women in southern Brazil. Revista do Instituto de Medicina Tropical de São Paulo. v. 55, n. 5, p. 315-321, 2013. Disponível em: <https: /Users/Cristina/Downloads/0036-4665-rimtsp-55-05-315.pdf> Acesso em 06 dec. 2016. |
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http://repositorio.furg.br/handle/1/6954 |
dc.identifier.doi.pt_BR.fl_str_mv |
: 10.1590/S0036-46652013000500004 |
identifier_str_mv |
CALDEIRA, Thaís Duquia Moraes; et al. Prevalence of herpes simplex virus type 2 and risk factors associated with this infection in women in southern Brazil. Revista do Instituto de Medicina Tropical de São Paulo. v. 55, n. 5, p. 315-321, 2013. Disponível em: <https: /Users/Cristina/Downloads/0036-4665-rimtsp-55-05-315.pdf> Acesso em 06 dec. 2016. : 10.1590/S0036-46652013000500004 |
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