Anatomical and functional changes of the brain of patientes with attention deficit disorder and hyperactivity
Autor(a) principal: | |
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Data de Publicação: | 2023 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Brazilian Journal of Implantology and Health Sciences |
Texto Completo: | https://bjihs.emnuvens.com.br/bjihs/article/view/375 |
Resumo: | Attention deficit hyperactivity disorder (ADHD) is a multifactorial neurodevelopmental disorder that is characterized by inattention, hyperactivity, restlessness, forgetfulness and impulsivity. There is evidence that ADHD is, in fact, a dysfunction of dopaminergic neurotransmission in the frontal area, subcortical regions and cerebral limbic region, evidenced through scientific studies, supported by neurological evidence and genetic studies. The objective of this research was to evaluate, through the scientific literature, the anatomical and functional alterations of the brain of patients with ADHD. This study consists of an integrative literature review, carried out with articles published in the databases of SciELO (Scientific Electronic Library Online), Google Scholar, online journals such as Revista Saúde em Foco and Associação Saúde da Família, and the books Principles of Anatomy and Physiology and Principles of Neuroscience, using the descriptors “alterations”, “anatomy”, “function”, “brain” and “ADHD”. The most relevant findings show that there is a decrease in the amount and activity of the white and gray matter of the brain in individuals with ADHD, in addition to evidence of a reduction in the prefrontal cortex in individuals with ADHD. In addition, it was noted that the deficit in the neurotransmitters dopamine and norepinephrine influence the symptoms of ADHD. Thus, it is concluded that ADHD presents important anatomical and functional alterations that affect the development of the brain circuit, generating a dysfunction and a change in neurobiological functioning, in addition to causing atypical functioning of the frontal lobe and structures associated with it, influencing in the inhibitory behavioral deficit and impairing the executive functions of the bearer of such clinical condition. |
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Brazilian Journal of Implantology and Health Sciences |
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Anatomical and functional changes of the brain of patientes with attention deficit disorder and hyperactivityAlterações anatômicas e funcionais do cérebro de pacientes com transtorno do déficit de atenção e hiperatividadeAlterações. Anatomia. Função. Cérebro. TDAH.Changes. Anatomy. Function. Brain. ADHD.Attention deficit hyperactivity disorder (ADHD) is a multifactorial neurodevelopmental disorder that is characterized by inattention, hyperactivity, restlessness, forgetfulness and impulsivity. There is evidence that ADHD is, in fact, a dysfunction of dopaminergic neurotransmission in the frontal area, subcortical regions and cerebral limbic region, evidenced through scientific studies, supported by neurological evidence and genetic studies. The objective of this research was to evaluate, through the scientific literature, the anatomical and functional alterations of the brain of patients with ADHD. This study consists of an integrative literature review, carried out with articles published in the databases of SciELO (Scientific Electronic Library Online), Google Scholar, online journals such as Revista Saúde em Foco and Associação Saúde da Família, and the books Principles of Anatomy and Physiology and Principles of Neuroscience, using the descriptors “alterations”, “anatomy”, “function”, “brain” and “ADHD”. The most relevant findings show that there is a decrease in the amount and activity of the white and gray matter of the brain in individuals with ADHD, in addition to evidence of a reduction in the prefrontal cortex in individuals with ADHD. In addition, it was noted that the deficit in the neurotransmitters dopamine and norepinephrine influence the symptoms of ADHD. Thus, it is concluded that ADHD presents important anatomical and functional alterations that affect the development of the brain circuit, generating a dysfunction and a change in neurobiological functioning, in addition to causing atypical functioning of the frontal lobe and structures associated with it, influencing in the inhibitory behavioral deficit and impairing the executive functions of the bearer of such clinical condition.O transtorno de déficit de atenção e hiperatividade (TDAH) é um distúbrio neurodesenvolvimental multifatorial que se caracteriza por desatenção, hiperatividade, inquietação, esquecimento e impulsividade. Existem evidências de que o TDAH se trata, de fato, de uma disfunção da neurotransmissão dopaminérgica na área frontal, regiões subcorticais e região límbica cerebral, evidenciada através de estudos científicos, apoiados por evidências neurológicas e estudos genéticos. O objetivo desta pesquisa foi avaliar, por meio da literatura científica, as alterações anatômicas e funcionais do cérebro de pacientes com TDAH. Este estudo consiste em uma revisão integrativa da literatura, realizada com artigos publicados nas bases de SciELO (Scientific Eletronic Library Online), Google Acadêmico, periódicos online, como a Revista Saúde em Foco e a Associação Saúde da Família, e os livros Princípios de Anatomia e Fisiologia e Princípios de neurociência, utilizando os descritores “alterações”, “anatomia”, “função”, “cérebro” e “TDAH”. As descobertas mais relevantes mostram que há a diminuição da quantidade e atividade da substância branca e cinzenta do cérebro de indivíduos com TDAH, além da evidência da redução do córtex pré-frontal em indivíduos com TDAH. Além disso, notou-se que o déficit nos neurotransmissores dopamina e norepinefrina influenciam na sintomatologia do TDAH. Desta forma, conclui-se que o TDAH apresenta alterações anatômicas e funcionais importantes que afetam o desenvolvimento do circuito cerebral, gerando uma disfunção e uma alteração no funcionamento neurobiológico, além de provocar um funcionamento atípico do lobo frontal e de estruturas associadas a ele, influenciando no déficit comportamental inibitório e prejudicando as funções executivas do portador de tal condição clínica.Specialized Dentistry Group2023-07-31info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://bjihs.emnuvens.com.br/bjihs/article/view/37510.36557/2674-8169.2023v5n4p27-41Brazilian Journal of Implantology and Health Sciences ; Vol. 5 No. 4 (2023): BJIHS QUALIS B3; 27-41Brazilian Journal of Implantology and Health Sciences ; Vol. 5 Núm. 4 (2023): BJIHS QUALIS B3; 27-41Brazilian Journal of Implantology and Health Sciences ; v. 5 n. 4 (2023): BJIHS QUALIS B3; 27-412674-8169reponame:Brazilian Journal of Implantology and Health Sciencesinstname:Grupo de Odontologia Especializada (GOE)instacron:GOEporhttps://bjihs.emnuvens.com.br/bjihs/article/view/375/448Copyright (c) 2023 Ana Raisla de Araújo Rodrigues, Ana Virgínia Moura e Silva, Gabriela Mota Vital Macedo, Maria Vitória Celestino Trindade Rodrigues, Raimundo Feitosa Neto, Kelly Palombit, Carla Maria de Carvalho Leite, Karinn de Araújo Soares Bastoshttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessRodrigues, Ana Raisla de AraújoMoura e Silva, Ana VirgíniaMacedo, Gabriela Mota VitalRodrigues, Maria Vitória Celestino TrindadeNeto, Raimundo FeitosaPalombit, KellyLeite, Carla Maria de CarvalhoBastos, Karinn de Araújo Soares2023-07-31T20:18:41Zoai:ojs.bjihs.emnuvens.com.br:article/375Revistahttps://bjihs.emnuvens.com.br/bjihsONGhttps://bjihs.emnuvens.com.br/bjihs/oaijournal.bjihs@periodicosbrasil.com.br2674-81692674-8169opendoar:2023-07-31T20:18:41Brazilian Journal of Implantology and Health Sciences - Grupo de Odontologia Especializada (GOE)false |
dc.title.none.fl_str_mv |
Anatomical and functional changes of the brain of patientes with attention deficit disorder and hyperactivity Alterações anatômicas e funcionais do cérebro de pacientes com transtorno do déficit de atenção e hiperatividade |
title |
Anatomical and functional changes of the brain of patientes with attention deficit disorder and hyperactivity |
spellingShingle |
Anatomical and functional changes of the brain of patientes with attention deficit disorder and hyperactivity Rodrigues, Ana Raisla de Araújo Alterações. Anatomia. Função. Cérebro. TDAH. Changes. Anatomy. Function. Brain. ADHD. |
title_short |
Anatomical and functional changes of the brain of patientes with attention deficit disorder and hyperactivity |
title_full |
Anatomical and functional changes of the brain of patientes with attention deficit disorder and hyperactivity |
title_fullStr |
Anatomical and functional changes of the brain of patientes with attention deficit disorder and hyperactivity |
title_full_unstemmed |
Anatomical and functional changes of the brain of patientes with attention deficit disorder and hyperactivity |
title_sort |
Anatomical and functional changes of the brain of patientes with attention deficit disorder and hyperactivity |
author |
Rodrigues, Ana Raisla de Araújo |
author_facet |
Rodrigues, Ana Raisla de Araújo Moura e Silva, Ana Virgínia Macedo, Gabriela Mota Vital Rodrigues, Maria Vitória Celestino Trindade Neto, Raimundo Feitosa Palombit, Kelly Leite, Carla Maria de Carvalho Bastos, Karinn de Araújo Soares |
author_role |
author |
author2 |
Moura e Silva, Ana Virgínia Macedo, Gabriela Mota Vital Rodrigues, Maria Vitória Celestino Trindade Neto, Raimundo Feitosa Palombit, Kelly Leite, Carla Maria de Carvalho Bastos, Karinn de Araújo Soares |
author2_role |
author author author author author author author |
dc.contributor.author.fl_str_mv |
Rodrigues, Ana Raisla de Araújo Moura e Silva, Ana Virgínia Macedo, Gabriela Mota Vital Rodrigues, Maria Vitória Celestino Trindade Neto, Raimundo Feitosa Palombit, Kelly Leite, Carla Maria de Carvalho Bastos, Karinn de Araújo Soares |
dc.subject.por.fl_str_mv |
Alterações. Anatomia. Função. Cérebro. TDAH. Changes. Anatomy. Function. Brain. ADHD. |
topic |
Alterações. Anatomia. Função. Cérebro. TDAH. Changes. Anatomy. Function. Brain. ADHD. |
description |
Attention deficit hyperactivity disorder (ADHD) is a multifactorial neurodevelopmental disorder that is characterized by inattention, hyperactivity, restlessness, forgetfulness and impulsivity. There is evidence that ADHD is, in fact, a dysfunction of dopaminergic neurotransmission in the frontal area, subcortical regions and cerebral limbic region, evidenced through scientific studies, supported by neurological evidence and genetic studies. The objective of this research was to evaluate, through the scientific literature, the anatomical and functional alterations of the brain of patients with ADHD. This study consists of an integrative literature review, carried out with articles published in the databases of SciELO (Scientific Electronic Library Online), Google Scholar, online journals such as Revista Saúde em Foco and Associação Saúde da Família, and the books Principles of Anatomy and Physiology and Principles of Neuroscience, using the descriptors “alterations”, “anatomy”, “function”, “brain” and “ADHD”. The most relevant findings show that there is a decrease in the amount and activity of the white and gray matter of the brain in individuals with ADHD, in addition to evidence of a reduction in the prefrontal cortex in individuals with ADHD. In addition, it was noted that the deficit in the neurotransmitters dopamine and norepinephrine influence the symptoms of ADHD. Thus, it is concluded that ADHD presents important anatomical and functional alterations that affect the development of the brain circuit, generating a dysfunction and a change in neurobiological functioning, in addition to causing atypical functioning of the frontal lobe and structures associated with it, influencing in the inhibitory behavioral deficit and impairing the executive functions of the bearer of such clinical condition. |
publishDate |
2023 |
dc.date.none.fl_str_mv |
2023-07-31 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://bjihs.emnuvens.com.br/bjihs/article/view/375 10.36557/2674-8169.2023v5n4p27-41 |
url |
https://bjihs.emnuvens.com.br/bjihs/article/view/375 |
identifier_str_mv |
10.36557/2674-8169.2023v5n4p27-41 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://bjihs.emnuvens.com.br/bjihs/article/view/375/448 |
dc.rights.driver.fl_str_mv |
https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Specialized Dentistry Group |
publisher.none.fl_str_mv |
Specialized Dentistry Group |
dc.source.none.fl_str_mv |
Brazilian Journal of Implantology and Health Sciences ; Vol. 5 No. 4 (2023): BJIHS QUALIS B3; 27-41 Brazilian Journal of Implantology and Health Sciences ; Vol. 5 Núm. 4 (2023): BJIHS QUALIS B3; 27-41 Brazilian Journal of Implantology and Health Sciences ; v. 5 n. 4 (2023): BJIHS QUALIS B3; 27-41 2674-8169 reponame:Brazilian Journal of Implantology and Health Sciences instname:Grupo de Odontologia Especializada (GOE) instacron:GOE |
instname_str |
Grupo de Odontologia Especializada (GOE) |
instacron_str |
GOE |
institution |
GOE |
reponame_str |
Brazilian Journal of Implantology and Health Sciences |
collection |
Brazilian Journal of Implantology and Health Sciences |
repository.name.fl_str_mv |
Brazilian Journal of Implantology and Health Sciences - Grupo de Odontologia Especializada (GOE) |
repository.mail.fl_str_mv |
journal.bjihs@periodicosbrasil.com.br |
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1796798438244876288 |