ROLE OF CUTANEOUS CYTOKINES IN PSORIASIS AND PREGNANCY: AN IMMUNOLOGICAL PERSPECTIVE

• Autor(a) principal: Silva , Sávio Dimas da
• Data de Publicação: 2023
• Outros Autores: Rocha , Maria Eduarda de Sá Bonifácio, Rêgo , Hosana Maria Araújo, Trindade , Leticia Dantas, Paiva , Felipe Alberto Dantas Pinto de, Gomes, Gabriel Rozendo Mendonça, Carvalho , Lizandra Cunha de, Gondim, Matheus Bezerra, Oporto , Vitória França de Oliveira, Montenegro, Rogério Batista, Salvador , Laísa Gomes, Bandeira , Thiago Maio, Chikui , Beatriz Yumi Osaki, Sampaio , Gabriella Pinheiro Castro, Barreto , Laís Cardozo
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Brazilian Journal of Implantology and Health Sciences
• Texto Completo: https://bjihs.emnuvens.com.br/bjihs/article/view/1093
• topic: Psoríase; Gravidez; Citocinas; Imunologia.; Psoriasis; Pregnancy; Cytokines; Immunology.

Introduction: The relationship between pregnancy and psoriasis is observed, as several studies and research indicate a direct relationship, in which immunological variations generated by pregnancy end up affecting and influencing the aforementioned disease. Those responsible for the skin's immunological reactions are Cytokines. Objective: Understand how Cytokine proteins act in relation to psoriasis in pregnant women. Methodology: A systematic literature review was carried out covering the years from January 2003 to December 2023. The study was based and guided by the question mentioned throughout the article. Results: Starting from the point that pregnant women present several immunological changes so that they can generate sustainability for the growth of the fetus, an increase in the number of so-called anti-inflammatory cytokines is noted, for example beta (TGF), which can reduce the psoriasis inflammation process. On the other hand, there are other types of Cytokine proteins that end up triggering and aggravating peeling and inflammatory lesions. Conclusion: Pregnant women end up having limitations to psoriasis treatments, since in most cases a personalized care strategy plan is needed according to the individual's clinical status and insurance so that it is possible that no type of complication occurs.