Antidepressants in Anxiety: A Comprehensive Approach to Efficacy and Mechanisms of Action.

• Autor(a) principal: Vasconcelos, José Lucas Moura
• Data de Publicação: 2024
• Outros Autores: Manfroi , Amabile, Filho , Antônio Carlos Gargioni, Pinaty , Carla Maria Zanelli, Evangelista , Danyllo Fagundes, Gregory , Gilmara Gabrielli, Fritsch , Giordana Gregório, Brunetta, Iara de Campos, Barros , Izadora Fernanda, Gonçalves , Kauara Marcelino, Brunetta , Lara de Campos, Rosa , Leonardo Gomes Silva, Lacerda, Marcos Vinicius Maldonado de Barros, Figueiredo, Maria Clara de Alencar, Menezes , Maria Eduarda Coelho de, Cenci , Maria Eduarda Fornari, Sansão, Maria Eduarda Miranda, Filho , Miguel Gramulha, Ceron , Nathalia Sofia Mayer, Dantas , Thais Torres Galindo, Oliveira, Thiago Rodrigues de
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Brazilian Journal of Implantology and Health Sciences
• Texto Completo: https://bjihs.emnuvens.com.br/bjihs/article/view/1291
• topic: Antidepressivos; Ansiedade; Tratamento; Medicamentos; Antidepressants; anxiety

This paper conducts a comprehensive literature review on the role of antidepressants in the treatment of anxiety. The analysis includes controlled clinical trials and systematic reviews addressing the efficacy of different classes of antidepressants, with a primary focus on Selective Serotonin Reuptake Inhibitors (SSRIs) and tricyclic antidepressants. The results indicate that SSRIs, such as escitalopram, consistently demonstrate efficacy in reducing anxiety symptoms compared to placebos. Additionally, tricyclic antidepressants, although less commonly prescribed, have proven effective in specific situations, such as in the treatment of social anxiety disorder. The research emphasizes the importance of personalized treatment, considering factors such as the side effect profile, comorbidities, and individual patient characteristics. This personalized approach emerges as crucial for optimizing clinical outcomes and minimizing potential adverse effects.