Hepatitis delta virus infection and Labrea hepatitis. Prevalence and role in fulminant hepatitis in the Amazon Basin

Detalhes bibliográficos
Autor(a) principal: Bensabath, Gilberta
Data de Publicação: 1987
Outros Autores: Hadler, Stephen C, Soares, Manoel do Carmo Pereira, Fields, Howard, Dias, Leonidas Braga, Popper, Hans, Maynard, James E
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Digital do Instituto Evandro Chagas (Patuá)
Texto Completo: http://patua.iec.gov.br//handle/iec/2728
Resumo: To define more exactly the epidemiology of delta virus infection and confirm its role in causing fulminant Labrea hepatitis in the Amazon Basin, we studied the prevalence of delta virus infection among persons with acute and chronic hepatitis B virus infection in the Boca do Acre district of the southern Amazon Basin. Delta virus infection was found in 24% of asymptomatic hepatitis B virus carriers, 29% of acute nonfulminant hepatitis B cases, 74% of fulminant hepatitis B cases, and 100% of chronic hepatitis B cases. Chronic delta virus infection occurred primarily in older children and adults, while acute and fulminant delta virus infection occurred in young children as well. In fulminant hepatitis cases, delta virus superinfection of hepatitis B virus carriers was the most common serological pattern; histopathologic examination showed features identical to those described in fulminant hepatitis cases of similar etiology in Colombia and Venezuela. Delta virus infection is highly endemic in the southern Amazon Basin and is the principal cause of Labrea hepatitis.
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spelling Bensabath, GilbertaHadler, Stephen CSoares, Manoel do Carmo PereiraFields, HowardDias, Leonidas BragaPopper, HansMaynard, James E2017-09-12T10:13:28Z2017-09-12T10:13:28Z1987BENSABATH, Gilberta et al. Hepatitis delta virus infection and Labrea hepatitis. Prevalence and role in fulminant hepatitis in the Amazon Basin. JAMA, v. 258, n. 4, p. 24-31, July 1987.DOI: https://doi.org/10.1001/jama.1987.03400040077025.0098-7484http://patua.iec.gov.br//handle/iec/272810.1001/jama.1987.03400040077025To define more exactly the epidemiology of delta virus infection and confirm its role in causing fulminant Labrea hepatitis in the Amazon Basin, we studied the prevalence of delta virus infection among persons with acute and chronic hepatitis B virus infection in the Boca do Acre district of the southern Amazon Basin. Delta virus infection was found in 24% of asymptomatic hepatitis B virus carriers, 29% of acute nonfulminant hepatitis B cases, 74% of fulminant hepatitis B cases, and 100% of chronic hepatitis B cases. Chronic delta virus infection occurred primarily in older children and adults, while acute and fulminant delta virus infection occurred in young children as well. In fulminant hepatitis cases, delta virus superinfection of hepatitis B virus carriers was the most common serological pattern; histopathologic examination showed features identical to those described in fulminant hepatitis cases of similar etiology in Colombia and Venezuela. Delta virus infection is highly endemic in the southern Amazon Basin and is the principal cause of Labrea hepatitis.Ministério da Saúde. Fundação Serviços de Saúde Pública. Instituto Evandro Chagas. Belém, PA, Brasil.Centers for Disease Control. Division of Viral Diseases. The Hepatitis Branch. Atlanta, GA, EUA.Ministério da Saúde. Fundação Serviços de Saúde Pública. Instituto Evandro Chagas. Belém, PA, Brasil.Centers for Disease Control. Division of Viral Diseases. The Hepatitis Branch. Atlanta, GA, EUA.Ministério da Saúde. Fundação Serviços de Saúde Pública. Instituto Evandro Chagas. Belém, PA, Brasil.City University of New York. Mount Sinai School of Medicine. The Stratton Laboratory for Study of Liver Diseases. New York, NY, EUA.Centers for Disease Control. Division of Viral Diseases. The Hepatitis Branch. Atlanta, GA, EUA.engAmerican Medical AssociationHepatitis delta virus infection and Labrea hepatitis. Prevalence and role in fulminant hepatitis in the Amazon Basininfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleVírus Delta da Hepatite / solamento & purificaçãoHepatite / diagnósticoHepatite B / complicaçõesHepatite B / epidemiologiaHepatite D / complicaçõesHepatite D / epidemiologiaBacia Amazônica do Sul (AC)Boca do Acre (AC)info:eu-repo/semantics/embargoedAccessreponame:Repositório Digital do Instituto Evandro Chagas (Patuá)instname:Instituto Evandro Chagas (IEC)instacron:IECLICENSElicense.txtlicense.txttext/plain; charset=utf-871https://patua.iec.gov.br/bitstreams/252d6952-b26d-43d3-a271-3418fe3300a7/download52f1732ea66fbd1123abe39f5373b797MD52ORIGINALAcesso Embargado.pdfAcesso Embargado.pdfapplication/pdf551083https://patua.iec.gov.br/bitstreams/dcfd4f6f-36fc-4caa-9a44-075f59184360/downloadc9a9c128e29cac82a5d7fdf3f4e6da73MD53TEXTHepatitis delta virus infection and Labrea hepatitis.pdf.txtHepatitis delta virus infection and Labrea hepatitis.pdf.txtExtracted texttext/plain2https://patua.iec.gov.br/bitstreams/63c7fdf7-4d43-4c6a-aef6-2c7aee84baa4/downloade1c06d85ae7b8b032bef47e42e4c08f9MD56Acesso Embargado.pdf.txtAcesso Embargado.pdf.txtExtracted texttext/plain2https://patua.iec.gov.br/bitstreams/1bfe180a-ef13-4d06-b451-8503683d20e4/downloade1c06d85ae7b8b032bef47e42e4c08f9MD58THUMBNAILHepatitis delta virus infection and Labrea hepatitis.pdf.jpgHepatitis delta virus infection and Labrea hepatitis.pdf.jpgGenerated Thumbnailimage/jpeg3095https://patua.iec.gov.br/bitstreams/f1818ea8-67e7-4bfa-894d-e7d4066d9cd3/download71859d578212107f7f8c49a4ce09d9eeMD57Acesso Embargado.pdf.jpgAcesso Embargado.pdf.jpgGenerated Thumbnailimage/jpeg3095https://patua.iec.gov.br/bitstreams/7aacedf2-c19a-41b4-9981-d7c693c5c3f1/download71859d578212107f7f8c49a4ce09d9eeMD59iec/27282023-05-22 14:06:51.799oai:patua.iec.gov.br:iec/2728https://patua.iec.gov.brRepositório InstitucionalPUBhttps://patua.iec.gov.br/oai/requestclariceneta@iec.gov.br || Biblioteca@iec.gov.bropendoar:2023-05-22T14:06:51Repositório Digital do Instituto Evandro Chagas (Patuá) - Instituto Evandro Chagas (IEC)falseVG9kb3Mgb3MgZG9jdW1lbnRvcyBkZXNzYSBjb2xlw6fDo28gc2VndWVtIGEgTGljZW7Dp2EgQ3JlYXRpdmUgY29tbW9ucy4=
dc.title.pt_BR.fl_str_mv Hepatitis delta virus infection and Labrea hepatitis. Prevalence and role in fulminant hepatitis in the Amazon Basin
title Hepatitis delta virus infection and Labrea hepatitis. Prevalence and role in fulminant hepatitis in the Amazon Basin
spellingShingle Hepatitis delta virus infection and Labrea hepatitis. Prevalence and role in fulminant hepatitis in the Amazon Basin
Bensabath, Gilberta
Vírus Delta da Hepatite / solamento & purificação
Hepatite / diagnóstico
Hepatite B / complicações
Hepatite B / epidemiologia
Hepatite D / complicações
Hepatite D / epidemiologia
Bacia Amazônica do Sul (AC)
Boca do Acre (AC)
title_short Hepatitis delta virus infection and Labrea hepatitis. Prevalence and role in fulminant hepatitis in the Amazon Basin
title_full Hepatitis delta virus infection and Labrea hepatitis. Prevalence and role in fulminant hepatitis in the Amazon Basin
title_fullStr Hepatitis delta virus infection and Labrea hepatitis. Prevalence and role in fulminant hepatitis in the Amazon Basin
title_full_unstemmed Hepatitis delta virus infection and Labrea hepatitis. Prevalence and role in fulminant hepatitis in the Amazon Basin
title_sort Hepatitis delta virus infection and Labrea hepatitis. Prevalence and role in fulminant hepatitis in the Amazon Basin
author Bensabath, Gilberta
author_facet Bensabath, Gilberta
Hadler, Stephen C
Soares, Manoel do Carmo Pereira
Fields, Howard
Dias, Leonidas Braga
Popper, Hans
Maynard, James E
author_role author
author2 Hadler, Stephen C
Soares, Manoel do Carmo Pereira
Fields, Howard
Dias, Leonidas Braga
Popper, Hans
Maynard, James E
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Bensabath, Gilberta
Hadler, Stephen C
Soares, Manoel do Carmo Pereira
Fields, Howard
Dias, Leonidas Braga
Popper, Hans
Maynard, James E
dc.subject.decsPrimary.pt_BR.fl_str_mv Vírus Delta da Hepatite / solamento & purificação
Hepatite / diagnóstico
Hepatite B / complicações
Hepatite B / epidemiologia
Hepatite D / complicações
Hepatite D / epidemiologia
Bacia Amazônica do Sul (AC)
Boca do Acre (AC)
topic Vírus Delta da Hepatite / solamento & purificação
Hepatite / diagnóstico
Hepatite B / complicações
Hepatite B / epidemiologia
Hepatite D / complicações
Hepatite D / epidemiologia
Bacia Amazônica do Sul (AC)
Boca do Acre (AC)
description To define more exactly the epidemiology of delta virus infection and confirm its role in causing fulminant Labrea hepatitis in the Amazon Basin, we studied the prevalence of delta virus infection among persons with acute and chronic hepatitis B virus infection in the Boca do Acre district of the southern Amazon Basin. Delta virus infection was found in 24% of asymptomatic hepatitis B virus carriers, 29% of acute nonfulminant hepatitis B cases, 74% of fulminant hepatitis B cases, and 100% of chronic hepatitis B cases. Chronic delta virus infection occurred primarily in older children and adults, while acute and fulminant delta virus infection occurred in young children as well. In fulminant hepatitis cases, delta virus superinfection of hepatitis B virus carriers was the most common serological pattern; histopathologic examination showed features identical to those described in fulminant hepatitis cases of similar etiology in Colombia and Venezuela. Delta virus infection is highly endemic in the southern Amazon Basin and is the principal cause of Labrea hepatitis.
publishDate 1987
dc.date.issued.fl_str_mv 1987
dc.date.accessioned.fl_str_mv 2017-09-12T10:13:28Z
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dc.identifier.citation.fl_str_mv BENSABATH, Gilberta et al. Hepatitis delta virus infection and Labrea hepatitis. Prevalence and role in fulminant hepatitis in the Amazon Basin. JAMA, v. 258, n. 4, p. 24-31, July 1987.DOI: https://doi.org/10.1001/jama.1987.03400040077025.
dc.identifier.uri.fl_str_mv http://patua.iec.gov.br//handle/iec/2728
dc.identifier.issn.-.fl_str_mv 0098-7484
dc.identifier.doi.pt_BR.fl_str_mv 10.1001/jama.1987.03400040077025
identifier_str_mv BENSABATH, Gilberta et al. Hepatitis delta virus infection and Labrea hepatitis. Prevalence and role in fulminant hepatitis in the Amazon Basin. JAMA, v. 258, n. 4, p. 24-31, July 1987.DOI: https://doi.org/10.1001/jama.1987.03400040077025.
0098-7484
10.1001/jama.1987.03400040077025
url http://patua.iec.gov.br//handle/iec/2728
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