Angiogenic activity of Synadenium umbellatum Pax latex

Detalhes bibliográficos
Autor(a) principal: Melo-Reis,PR.
Data de Publicação: 2010
Outros Autores: Andrade,LS., Silva,CB., Araújo,LMM., Pereira,MS., Mrue,F., Chen-Chen,L.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Brazilian Journal of Biology
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1519-69842010000100026
Resumo: Synadenium umbellatum Pax, popularly known as "cola-nota", is a medicinal plant that grows in tropical regions. Latex of this plant is used to treat various diseases such as diabetes mellitus, Hansen´s disease, tripanosomiases, leukemia and several malignant tumors. In the present study, the angiogenic activity of S. umbellatum latex was evaluated using the chick embryo chorioallantoic membrane (CAM) assay. Results showed significant increase of the vascular net (p < 0.05) compared to the negative control (H2O). The histological analysis was in accordance with the results obtained. In conclusion, our data indicate that S. umbellatum latex, under the conditions of this research, presented angiogenic effect.
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spelling Angiogenic activity of Synadenium umbellatum Pax latexAngiogenesislatexchick chorioallantoic membraneSynadenium umbellatumSynadenium umbellatum Pax, popularly known as "cola-nota", is a medicinal plant that grows in tropical regions. Latex of this plant is used to treat various diseases such as diabetes mellitus, Hansen´s disease, tripanosomiases, leukemia and several malignant tumors. In the present study, the angiogenic activity of S. umbellatum latex was evaluated using the chick embryo chorioallantoic membrane (CAM) assay. Results showed significant increase of the vascular net (p < 0.05) compared to the negative control (H2O). The histological analysis was in accordance with the results obtained. In conclusion, our data indicate that S. umbellatum latex, under the conditions of this research, presented angiogenic effect.Instituto Internacional de Ecologia2010-02-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1519-69842010000100026Brazilian Journal of Biology v.70 n.1 2010reponame:Brazilian Journal of Biologyinstname:Instituto Internacional de Ecologia (IIE)instacron:IIE10.1590/S1519-69842010000100026info:eu-repo/semantics/openAccessMelo-Reis,PR.Andrade,LS.Silva,CB.Araújo,LMM.Pereira,MS.Mrue,F.Chen-Chen,L.eng2010-03-04T00:00:00Zoai:scielo:S1519-69842010000100026Revistahttps://www.scielo.br/j/bjb/https://old.scielo.br/oai/scielo-oai.phpbjb@bjb.com.br||bjb@bjb.com.br1678-43751519-6984opendoar:2010-03-04T00:00Brazilian Journal of Biology - Instituto Internacional de Ecologia (IIE)false
dc.title.none.fl_str_mv Angiogenic activity of Synadenium umbellatum Pax latex
title Angiogenic activity of Synadenium umbellatum Pax latex
spellingShingle Angiogenic activity of Synadenium umbellatum Pax latex
Melo-Reis,PR.
Angiogenesis
latex
chick chorioallantoic membrane
Synadenium umbellatum
title_short Angiogenic activity of Synadenium umbellatum Pax latex
title_full Angiogenic activity of Synadenium umbellatum Pax latex
title_fullStr Angiogenic activity of Synadenium umbellatum Pax latex
title_full_unstemmed Angiogenic activity of Synadenium umbellatum Pax latex
title_sort Angiogenic activity of Synadenium umbellatum Pax latex
author Melo-Reis,PR.
author_facet Melo-Reis,PR.
Andrade,LS.
Silva,CB.
Araújo,LMM.
Pereira,MS.
Mrue,F.
Chen-Chen,L.
author_role author
author2 Andrade,LS.
Silva,CB.
Araújo,LMM.
Pereira,MS.
Mrue,F.
Chen-Chen,L.
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Melo-Reis,PR.
Andrade,LS.
Silva,CB.
Araújo,LMM.
Pereira,MS.
Mrue,F.
Chen-Chen,L.
dc.subject.por.fl_str_mv Angiogenesis
latex
chick chorioallantoic membrane
Synadenium umbellatum
topic Angiogenesis
latex
chick chorioallantoic membrane
Synadenium umbellatum
description Synadenium umbellatum Pax, popularly known as "cola-nota", is a medicinal plant that grows in tropical regions. Latex of this plant is used to treat various diseases such as diabetes mellitus, Hansen´s disease, tripanosomiases, leukemia and several malignant tumors. In the present study, the angiogenic activity of S. umbellatum latex was evaluated using the chick embryo chorioallantoic membrane (CAM) assay. Results showed significant increase of the vascular net (p < 0.05) compared to the negative control (H2O). The histological analysis was in accordance with the results obtained. In conclusion, our data indicate that S. umbellatum latex, under the conditions of this research, presented angiogenic effect.
publishDate 2010
dc.date.none.fl_str_mv 2010-02-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1519-69842010000100026
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1519-69842010000100026
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1519-69842010000100026
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Instituto Internacional de Ecologia
publisher.none.fl_str_mv Instituto Internacional de Ecologia
dc.source.none.fl_str_mv Brazilian Journal of Biology v.70 n.1 2010
reponame:Brazilian Journal of Biology
instname:Instituto Internacional de Ecologia (IIE)
instacron:IIE
instname_str Instituto Internacional de Ecologia (IIE)
instacron_str IIE
institution IIE
reponame_str Brazilian Journal of Biology
collection Brazilian Journal of Biology
repository.name.fl_str_mv Brazilian Journal of Biology - Instituto Internacional de Ecologia (IIE)
repository.mail.fl_str_mv bjb@bjb.com.br||bjb@bjb.com.br
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