Bioactivity evaluation against Artemia salina Leach of medicinal plants used in Brazilian Northeastern folk medicine

Detalhes bibliográficos
Autor(a) principal: Arcanjo,DDR.
Data de Publicação: 2012
Outros Autores: Albuquerque,ACM., Melo-Neto,B., Santana,LCLR., Medeiros,MGF, Citó,AMGL.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Brazilian Journal of Biology
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1519-69842012000300013
Resumo: The brine shrimp (Artemia salina Leach) lethality bioassay offers an advantage in standardization and quality control of botanical products. This test is well correlated with antitumor activity (cytotoxicity) and can be used to monitor the activity of bioactive natural products. This paper reports the bioactivity of ethanol extracts from seven medicinal plants from the Northeast of Brazil (Acmella uliginosa, Ageratum conyzoides, Eugenia uniflora, Plectranthus neochilus, Moringa oleifera, Justicia pectoralis and Equisetum sp.) against Artemia salina. Biological activity was evaluated for extracts at 1, 10, 100, and 1000 µg/mL in triplicate, and the mean lethal concentration values (LC50) were obtained by probit analysis. The species Acmella uliginosa showed the highest bioactivity, and its flower extract was more active than its leaf extract.
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spelling Bioactivity evaluation against Artemia salina Leach of medicinal plants used in Brazilian Northeastern folk medicinemedicinal plantsbioassaylethalityArtemia salinaThe brine shrimp (Artemia salina Leach) lethality bioassay offers an advantage in standardization and quality control of botanical products. This test is well correlated with antitumor activity (cytotoxicity) and can be used to monitor the activity of bioactive natural products. This paper reports the bioactivity of ethanol extracts from seven medicinal plants from the Northeast of Brazil (Acmella uliginosa, Ageratum conyzoides, Eugenia uniflora, Plectranthus neochilus, Moringa oleifera, Justicia pectoralis and Equisetum sp.) against Artemia salina. Biological activity was evaluated for extracts at 1, 10, 100, and 1000 µg/mL in triplicate, and the mean lethal concentration values (LC50) were obtained by probit analysis. The species Acmella uliginosa showed the highest bioactivity, and its flower extract was more active than its leaf extract.Instituto Internacional de Ecologia2012-08-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1519-69842012000300013Brazilian Journal of Biology v.72 n.3 2012reponame:Brazilian Journal of Biologyinstname:Instituto Internacional de Ecologia (IIE)instacron:IIE10.1590/S1519-69842012000300013info:eu-repo/semantics/openAccessArcanjo,DDR.Albuquerque,ACM.Melo-Neto,B.Santana,LCLR.Medeiros,MGFCitó,AMGL.eng2012-09-14T00:00:00Zoai:scielo:S1519-69842012000300013Revistahttps://www.scielo.br/j/bjb/https://old.scielo.br/oai/scielo-oai.phpbjb@bjb.com.br||bjb@bjb.com.br1678-43751519-6984opendoar:2012-09-14T00:00Brazilian Journal of Biology - Instituto Internacional de Ecologia (IIE)false
dc.title.none.fl_str_mv Bioactivity evaluation against Artemia salina Leach of medicinal plants used in Brazilian Northeastern folk medicine
title Bioactivity evaluation against Artemia salina Leach of medicinal plants used in Brazilian Northeastern folk medicine
spellingShingle Bioactivity evaluation against Artemia salina Leach of medicinal plants used in Brazilian Northeastern folk medicine
Arcanjo,DDR.
medicinal plants
bioassay
lethality
Artemia salina
title_short Bioactivity evaluation against Artemia salina Leach of medicinal plants used in Brazilian Northeastern folk medicine
title_full Bioactivity evaluation against Artemia salina Leach of medicinal plants used in Brazilian Northeastern folk medicine
title_fullStr Bioactivity evaluation against Artemia salina Leach of medicinal plants used in Brazilian Northeastern folk medicine
title_full_unstemmed Bioactivity evaluation against Artemia salina Leach of medicinal plants used in Brazilian Northeastern folk medicine
title_sort Bioactivity evaluation against Artemia salina Leach of medicinal plants used in Brazilian Northeastern folk medicine
author Arcanjo,DDR.
author_facet Arcanjo,DDR.
Albuquerque,ACM.
Melo-Neto,B.
Santana,LCLR.
Medeiros,MGF
Citó,AMGL.
author_role author
author2 Albuquerque,ACM.
Melo-Neto,B.
Santana,LCLR.
Medeiros,MGF
Citó,AMGL.
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Arcanjo,DDR.
Albuquerque,ACM.
Melo-Neto,B.
Santana,LCLR.
Medeiros,MGF
Citó,AMGL.
dc.subject.por.fl_str_mv medicinal plants
bioassay
lethality
Artemia salina
topic medicinal plants
bioassay
lethality
Artemia salina
description The brine shrimp (Artemia salina Leach) lethality bioassay offers an advantage in standardization and quality control of botanical products. This test is well correlated with antitumor activity (cytotoxicity) and can be used to monitor the activity of bioactive natural products. This paper reports the bioactivity of ethanol extracts from seven medicinal plants from the Northeast of Brazil (Acmella uliginosa, Ageratum conyzoides, Eugenia uniflora, Plectranthus neochilus, Moringa oleifera, Justicia pectoralis and Equisetum sp.) against Artemia salina. Biological activity was evaluated for extracts at 1, 10, 100, and 1000 µg/mL in triplicate, and the mean lethal concentration values (LC50) were obtained by probit analysis. The species Acmella uliginosa showed the highest bioactivity, and its flower extract was more active than its leaf extract.
publishDate 2012
dc.date.none.fl_str_mv 2012-08-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1519-69842012000300013
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1519-69842012000300013
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1519-69842012000300013
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Instituto Internacional de Ecologia
publisher.none.fl_str_mv Instituto Internacional de Ecologia
dc.source.none.fl_str_mv Brazilian Journal of Biology v.72 n.3 2012
reponame:Brazilian Journal of Biology
instname:Instituto Internacional de Ecologia (IIE)
instacron:IIE
instname_str Instituto Internacional de Ecologia (IIE)
instacron_str IIE
institution IIE
reponame_str Brazilian Journal of Biology
collection Brazilian Journal of Biology
repository.name.fl_str_mv Brazilian Journal of Biology - Instituto Internacional de Ecologia (IIE)
repository.mail.fl_str_mv bjb@bjb.com.br||bjb@bjb.com.br
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