Multiple myeloma: five-year experience at a University Hospital
Autor(a) principal: | |
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Data de Publicação: | 2011 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Einstein (São Paulo) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082011000200145 |
Resumo: | Objective: To present a descriptive analysis of patients diagnosed with multiple myeloma, correlating it with mortality. Methods: A retrospective study that analyzed consecutive patients diagnosed with multiple myeloma under follow-up at the Faculdade de Medicina do ABC from 2006 to 2010. Results: The median age was 58.5 years. Anemia was observed upon diagnosis in 87% of patients, hypercalcemia in 38%, and creatinine levels higher than 2 mg/dL in 19%. M protein was detected in 85.7%. The five-year survival rate was 74.6%. Multivariate analysis showed statistical significance for Durie-Salmon staging (p = 0.037). The International Staging System and immunoglobulin type did not correlate significantly with survival of the group. Conclusion: This set of cases from a tertiary public healthcare service reflect the approach of multiple myeloma in a predominantly young population with advanced clinical staging, with results comparable to those of the literature. |
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Multiple myeloma: five-year experience at a University HospitalMultiple myeloma/therapyNeoplasm stagingSurvival Objective: To present a descriptive analysis of patients diagnosed with multiple myeloma, correlating it with mortality. Methods: A retrospective study that analyzed consecutive patients diagnosed with multiple myeloma under follow-up at the Faculdade de Medicina do ABC from 2006 to 2010. Results: The median age was 58.5 years. Anemia was observed upon diagnosis in 87% of patients, hypercalcemia in 38%, and creatinine levels higher than 2 mg/dL in 19%. M protein was detected in 85.7%. The five-year survival rate was 74.6%. Multivariate analysis showed statistical significance for Durie-Salmon staging (p = 0.037). The International Staging System and immunoglobulin type did not correlate significantly with survival of the group. Conclusion: This set of cases from a tertiary public healthcare service reflect the approach of multiple myeloma in a predominantly young population with advanced clinical staging, with results comparable to those of the literature.Instituto Israelita de Ensino e Pesquisa Albert Einstein2011-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082011000200145einstein (São Paulo) v.9 n.2 2011reponame:Einstein (São Paulo)instname:Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE)instacron:IIEPAE10.1590/s1679-45082011ao2006info:eu-repo/semantics/openAccessTodaro,JulianaBigonha,JandeyBorducchi,Davimar Miranda MacielMatos,Leandro LuongoTrufelli,Damila CristinaSales,Suzane Martines Alves deShiroma,Marina Rampazzo Del ValheGiglio,Auro deleng2017-03-14T00:00:00Zoai:scielo:S1679-45082011000200145Revistahttps://journal.einstein.br/pt-br/ONGhttps://old.scielo.br/oai/scielo-oai.php||revista@einstein.br2317-63851679-4508opendoar:2017-03-14T00:00Einstein (São Paulo) - Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE)false |
dc.title.none.fl_str_mv |
Multiple myeloma: five-year experience at a University Hospital |
title |
Multiple myeloma: five-year experience at a University Hospital |
spellingShingle |
Multiple myeloma: five-year experience at a University Hospital Todaro,Juliana Multiple myeloma/therapy Neoplasm staging Survival |
title_short |
Multiple myeloma: five-year experience at a University Hospital |
title_full |
Multiple myeloma: five-year experience at a University Hospital |
title_fullStr |
Multiple myeloma: five-year experience at a University Hospital |
title_full_unstemmed |
Multiple myeloma: five-year experience at a University Hospital |
title_sort |
Multiple myeloma: five-year experience at a University Hospital |
author |
Todaro,Juliana |
author_facet |
Todaro,Juliana Bigonha,Jandey Borducchi,Davimar Miranda Maciel Matos,Leandro Luongo Trufelli,Damila Cristina Sales,Suzane Martines Alves de Shiroma,Marina Rampazzo Del Valhe Giglio,Auro del |
author_role |
author |
author2 |
Bigonha,Jandey Borducchi,Davimar Miranda Maciel Matos,Leandro Luongo Trufelli,Damila Cristina Sales,Suzane Martines Alves de Shiroma,Marina Rampazzo Del Valhe Giglio,Auro del |
author2_role |
author author author author author author author |
dc.contributor.author.fl_str_mv |
Todaro,Juliana Bigonha,Jandey Borducchi,Davimar Miranda Maciel Matos,Leandro Luongo Trufelli,Damila Cristina Sales,Suzane Martines Alves de Shiroma,Marina Rampazzo Del Valhe Giglio,Auro del |
dc.subject.por.fl_str_mv |
Multiple myeloma/therapy Neoplasm staging Survival |
topic |
Multiple myeloma/therapy Neoplasm staging Survival |
description |
Objective: To present a descriptive analysis of patients diagnosed with multiple myeloma, correlating it with mortality. Methods: A retrospective study that analyzed consecutive patients diagnosed with multiple myeloma under follow-up at the Faculdade de Medicina do ABC from 2006 to 2010. Results: The median age was 58.5 years. Anemia was observed upon diagnosis in 87% of patients, hypercalcemia in 38%, and creatinine levels higher than 2 mg/dL in 19%. M protein was detected in 85.7%. The five-year survival rate was 74.6%. Multivariate analysis showed statistical significance for Durie-Salmon staging (p = 0.037). The International Staging System and immunoglobulin type did not correlate significantly with survival of the group. Conclusion: This set of cases from a tertiary public healthcare service reflect the approach of multiple myeloma in a predominantly young population with advanced clinical staging, with results comparable to those of the literature. |
publishDate |
2011 |
dc.date.none.fl_str_mv |
2011-06-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082011000200145 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082011000200145 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/s1679-45082011ao2006 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Instituto Israelita de Ensino e Pesquisa Albert Einstein |
publisher.none.fl_str_mv |
Instituto Israelita de Ensino e Pesquisa Albert Einstein |
dc.source.none.fl_str_mv |
einstein (São Paulo) v.9 n.2 2011 reponame:Einstein (São Paulo) instname:Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE) instacron:IIEPAE |
instname_str |
Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE) |
instacron_str |
IIEPAE |
institution |
IIEPAE |
reponame_str |
Einstein (São Paulo) |
collection |
Einstein (São Paulo) |
repository.name.fl_str_mv |
Einstein (São Paulo) - Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE) |
repository.mail.fl_str_mv |
||revista@einstein.br |
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1752129906193465344 |