Serum level of vitamin D3 in cutaneous melanoma
Autor(a) principal: | |
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Data de Publicação: | 2014 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Einstein (São Paulo) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082014000400473 |
Resumo: | Objective To compare the level of vitamin D3 in cutaneous melanoma patients, with or without disease activity, with reference values and with patients from a general hospital.Methods The serum levels of vitamin D3 were measured in cutaneous melanoma patients, aged 20 to 88 years, both genders, from January 2010 to December 2013. The samples from the general group were processed at Hospital Israelita Albert Einstein (control group). Data analysis was performed using the Statistics software.Results A total of 100 patients were studied, 54 of them men, with mean age of 54.67 years, and 95 Caucasian. Out of these 100 patients, 17 had active disease. The average levels of vitamin D3 in the melanoma patients were lower than the level considered sufficient, but above the average of the control group. Both groups (with or without active disease) of patients showed a similar distribution of vitamin D3 deficiency.Conclusion Vitamin D3 levels in melanoma patients were higher than those of general patients and lower than the reference level. If the reference values are appropriate, a large part of the population had insufficient levels of vitamin D, including those with melanoma, or else, this standard needs to be reevaluated. No difference in vitamin D3 levels was found among melanoma patients with or without active disease. More comprehensive research is needed to assess the relation between vitamin D and melanoma. |
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Serum level of vitamin D3 in cutaneous melanomaCalcifediolCholecalciferolReceptors, calcitriolVitamin D deficiencyMelanomaImmune systemObjective To compare the level of vitamin D3 in cutaneous melanoma patients, with or without disease activity, with reference values and with patients from a general hospital.Methods The serum levels of vitamin D3 were measured in cutaneous melanoma patients, aged 20 to 88 years, both genders, from January 2010 to December 2013. The samples from the general group were processed at Hospital Israelita Albert Einstein (control group). Data analysis was performed using the Statistics software.Results A total of 100 patients were studied, 54 of them men, with mean age of 54.67 years, and 95 Caucasian. Out of these 100 patients, 17 had active disease. The average levels of vitamin D3 in the melanoma patients were lower than the level considered sufficient, but above the average of the control group. Both groups (with or without active disease) of patients showed a similar distribution of vitamin D3 deficiency.Conclusion Vitamin D3 levels in melanoma patients were higher than those of general patients and lower than the reference level. If the reference values are appropriate, a large part of the population had insufficient levels of vitamin D, including those with melanoma, or else, this standard needs to be reevaluated. No difference in vitamin D3 levels was found among melanoma patients with or without active disease. More comprehensive research is needed to assess the relation between vitamin D and melanoma.Instituto Israelita de Ensino e Pesquisa Albert Einstein2014-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082014000400473einstein (São Paulo) v.12 n.4 2014reponame:Einstein (São Paulo)instname:Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE)instacron:IIEPAE10.1590/S1679-45082014AO3090info:eu-repo/semantics/openAccessOliveira Filho,Renato Santos deOliveira,Daniel Arcuschin deMartinho,Vitor Augusto MelãoAntoneli,Célia Beatriz GianottiMarcussi,Ludmilla Altino de LimaFerreira,Carlos Eduardo dos Santoseng2015-09-10T00:00:00Zoai:scielo:S1679-45082014000400473Revistahttps://journal.einstein.br/pt-br/ONGhttps://old.scielo.br/oai/scielo-oai.php||revista@einstein.br2317-63851679-4508opendoar:2015-09-10T00:00Einstein (São Paulo) - Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE)false |
dc.title.none.fl_str_mv |
Serum level of vitamin D3 in cutaneous melanoma |
title |
Serum level of vitamin D3 in cutaneous melanoma |
spellingShingle |
Serum level of vitamin D3 in cutaneous melanoma Oliveira Filho,Renato Santos de Calcifediol Cholecalciferol Receptors, calcitriol Vitamin D deficiency Melanoma Immune system |
title_short |
Serum level of vitamin D3 in cutaneous melanoma |
title_full |
Serum level of vitamin D3 in cutaneous melanoma |
title_fullStr |
Serum level of vitamin D3 in cutaneous melanoma |
title_full_unstemmed |
Serum level of vitamin D3 in cutaneous melanoma |
title_sort |
Serum level of vitamin D3 in cutaneous melanoma |
author |
Oliveira Filho,Renato Santos de |
author_facet |
Oliveira Filho,Renato Santos de Oliveira,Daniel Arcuschin de Martinho,Vitor Augusto Melão Antoneli,Célia Beatriz Gianotti Marcussi,Ludmilla Altino de Lima Ferreira,Carlos Eduardo dos Santos |
author_role |
author |
author2 |
Oliveira,Daniel Arcuschin de Martinho,Vitor Augusto Melão Antoneli,Célia Beatriz Gianotti Marcussi,Ludmilla Altino de Lima Ferreira,Carlos Eduardo dos Santos |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Oliveira Filho,Renato Santos de Oliveira,Daniel Arcuschin de Martinho,Vitor Augusto Melão Antoneli,Célia Beatriz Gianotti Marcussi,Ludmilla Altino de Lima Ferreira,Carlos Eduardo dos Santos |
dc.subject.por.fl_str_mv |
Calcifediol Cholecalciferol Receptors, calcitriol Vitamin D deficiency Melanoma Immune system |
topic |
Calcifediol Cholecalciferol Receptors, calcitriol Vitamin D deficiency Melanoma Immune system |
description |
Objective To compare the level of vitamin D3 in cutaneous melanoma patients, with or without disease activity, with reference values and with patients from a general hospital.Methods The serum levels of vitamin D3 were measured in cutaneous melanoma patients, aged 20 to 88 years, both genders, from January 2010 to December 2013. The samples from the general group were processed at Hospital Israelita Albert Einstein (control group). Data analysis was performed using the Statistics software.Results A total of 100 patients were studied, 54 of them men, with mean age of 54.67 years, and 95 Caucasian. Out of these 100 patients, 17 had active disease. The average levels of vitamin D3 in the melanoma patients were lower than the level considered sufficient, but above the average of the control group. Both groups (with or without active disease) of patients showed a similar distribution of vitamin D3 deficiency.Conclusion Vitamin D3 levels in melanoma patients were higher than those of general patients and lower than the reference level. If the reference values are appropriate, a large part of the population had insufficient levels of vitamin D, including those with melanoma, or else, this standard needs to be reevaluated. No difference in vitamin D3 levels was found among melanoma patients with or without active disease. More comprehensive research is needed to assess the relation between vitamin D and melanoma. |
publishDate |
2014 |
dc.date.none.fl_str_mv |
2014-12-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082014000400473 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082014000400473 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S1679-45082014AO3090 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Instituto Israelita de Ensino e Pesquisa Albert Einstein |
publisher.none.fl_str_mv |
Instituto Israelita de Ensino e Pesquisa Albert Einstein |
dc.source.none.fl_str_mv |
einstein (São Paulo) v.12 n.4 2014 reponame:Einstein (São Paulo) instname:Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE) instacron:IIEPAE |
instname_str |
Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE) |
instacron_str |
IIEPAE |
institution |
IIEPAE |
reponame_str |
Einstein (São Paulo) |
collection |
Einstein (São Paulo) |
repository.name.fl_str_mv |
Einstein (São Paulo) - Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE) |
repository.mail.fl_str_mv |
||revista@einstein.br |
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1752129907523059712 |