Prevalence of priapism in individuals with sickle cell disease and implications on male sexual function

• Autor(a) principal: Alvaia,Mateus Andrade
• Data de Publicação: 2020
• Outros Autores: Maia,Heros Aureliano Antunes da Silva, Nelli,Alana de Medeiros, Guimarães,Carina Oliveira Silva, Carvalho,Evanilda Souza de Santana, Netto,José Murillo Bastos, Miranda,Eduardo de Paula, Gomes,Cristiano Mendes, Bessa Júnior,José de
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Einstein (São Paulo)
• Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082020000100252
• topic: Anemmia, sickle cell; Priapism/epidemiology; Erectile dysfunction; Sexuality

ABSTRACT Objective To evaluate epidemiological aspects of priapism in patients with sickle cell disease, and these aspects impact on adult sexual function. Methods This was a cross-sectional study including individuals with sickle cell disease who were evaluated at a reference center for sickle cell. Participants completed a structured questionnaire about their sociodemographic characteristics and priapism events. Sexual function was assessed using validated two instruments, the Erection Hardness Score and one about the sex life satisfaction. Results Sixty-four individuals with median aged of 12 (7 to 28) years were interviewed. The prevalence of priapism was 35.9% (23/64). The earliest priapism episode occurred at 2 years of age and the latest at 42 years. The statistical projection was that 71.1% of individuals of the study would have at least one episode of priapism throughout life. Patients with episodes of priapism (10/23) had significantly worse erectile function Erection Hardness Score of 2 [1-3]; p=0.01 and were less satisfied with sexual life 3 [3-5]; p=0.02. Conclusion Priapism is usually present in childhood, and severe episodes are associated with cavernous damage, impairment in the quality of the erection, and lower sexual satisfaction.