Oxybutynin treatment for hyperhidrosis: a comparative analysis between genders

• Autor(a) principal: Wolosker,Nelson
• Data de Publicação: 2012
• Outros Autores: Krutman,Mariana, Campdell,Taiz Pereira Donozo Almeida, Kauffman,Paulo, Campos,Jose Ribas Milanez de, Puech-Leão,Pedro
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Einstein (São Paulo)
• Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082012000400002
• topic: Hyperhidrosis/drug therapy; Mandelic acids/therapeutic use; Mandelic acids/administration & dosage; Hand/pathology; Axilla/pathology; Quality of life; Male; Female

OBJECTIVE: To assess the results of palmar and axillary hyperhidrosis treatment in males and females using low doses of oxybutynin. METHODS: A retrospective analysis was conducted in 395 women and 170 men followed up in our service with complaint of palmar and axillary hyperhidrosis. RESULTS: A total of 70% of patients in both groups presented partial or great improvement in the level of hyperhidrosis after treatment. The best results were obtained in the female group, in which 40% classified their improvement as "great". Approximately 70% of the patients in both groups improved their quality of life after medical therapy and 30% presented no change in condition. CONCLUSION: Gender is not a factor that significantly interferes in oxybutynin treatment results. Quality of life indices and clinical improvement level were similar in men and women.