Acute schistosomiasis: clinical, diagnostic and therapeutic features

Detalhes bibliográficos
Autor(a) principal: Lambertucci, J. R.
Data de Publicação: 1993
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista do Instituto de Medicina Tropical de São Paulo
Texto Completo: https://www.revistas.usp.br/rimtsp/article/view/29076
Resumo: Three distinct syndromes caused by schistosomiasis have been described: cercarial dermatitis or swimmer's itch, acute schistosomiasis or Katayama fever, and chronic schistosomiasis. Complications of acute schistosomiasis have also been reported. The absence of a serological marker for the acute stage has hindered early diagnosis and treatment. Recently, an ELISA test using KLH (keyhole limpet haemocyanin) as antigen, has proved useful in differentiating acute from chronic schistosomiasis mansoni. Clinical and experimental evidence indicate that steroids act synergistically with schistosomicides in the treatment of Katayama syndrome. In this paper, clinical, diagnostic and therapeutic features of acute schistosomiasis are updated.
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spelling Acute schistosomiasis: clinical, diagnostic and therapeutic features Esquistossomose aguda: aspectos clínicos, diagnósticos e terapêuticos Acute schistosomiasisOxamniquinePraziquantelCorticosteroids Three distinct syndromes caused by schistosomiasis have been described: cercarial dermatitis or swimmer's itch, acute schistosomiasis or Katayama fever, and chronic schistosomiasis. Complications of acute schistosomiasis have also been reported. The absence of a serological marker for the acute stage has hindered early diagnosis and treatment. Recently, an ELISA test using KLH (keyhole limpet haemocyanin) as antigen, has proved useful in differentiating acute from chronic schistosomiasis mansoni. Clinical and experimental evidence indicate that steroids act synergistically with schistosomicides in the treatment of Katayama syndrome. In this paper, clinical, diagnostic and therapeutic features of acute schistosomiasis are updated. A esquistossomose apresenta-se clinicamente em três formas distintas: dermatite cercariana, esquistossomose aguda ou febre de Katayama e esquistossomose crônica. Há na literatura relatos de complicações da fase aguda. A ausencia de um marcador sorológico simples e confiável tem dificultado o diagnóstico precoce e, como consequência, o tratamento adequado de pacientes na fase aguda da doença. Recentemente, o teste de ELISA, realizado com o antígeno KLM (hemocianina do caramujo Megathura crenulata), tem se mostrado util na identificação dos pacientes com febre de Katayama. Evidências clínicas e experimentais apontam no sentido de uma ação sinérgica entre os corticosteróides e os esquistossomicidas no tratamento da esquistossomose toxêmica. Neste artigo, alguns aspectos clínicos, diagnósticos e terapêuticos da esquistossomose aguda são atualizados. Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo1993-10-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/rimtsp/article/view/29076Revista do Instituto de Medicina Tropical de São Paulo; Vol. 35 No. 5 (1993); 399-404 Revista do Instituto de Medicina Tropical de São Paulo; Vol. 35 Núm. 5 (1993); 399-404 Revista do Instituto de Medicina Tropical de São Paulo; v. 35 n. 5 (1993); 399-404 1678-99460036-4665reponame:Revista do Instituto de Medicina Tropical de São Pauloinstname:Instituto de Medicina Tropical (IMT)instacron:IMTenghttps://www.revistas.usp.br/rimtsp/article/view/29076/30933Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Pauloinfo:eu-repo/semantics/openAccessLambertucci, J. R.2012-07-02T01:36:02Zoai:revistas.usp.br:article/29076Revistahttp://www.revistas.usp.br/rimtsp/indexPUBhttps://www.revistas.usp.br/rimtsp/oai||revimtsp@usp.br1678-99460036-4665opendoar:2012-07-02T01:36:02Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT)false
dc.title.none.fl_str_mv Acute schistosomiasis: clinical, diagnostic and therapeutic features
Esquistossomose aguda: aspectos clínicos, diagnósticos e terapêuticos
title Acute schistosomiasis: clinical, diagnostic and therapeutic features
spellingShingle Acute schistosomiasis: clinical, diagnostic and therapeutic features
Lambertucci, J. R.
Acute schistosomiasis
Oxamniquine
Praziquantel
Corticosteroids
title_short Acute schistosomiasis: clinical, diagnostic and therapeutic features
title_full Acute schistosomiasis: clinical, diagnostic and therapeutic features
title_fullStr Acute schistosomiasis: clinical, diagnostic and therapeutic features
title_full_unstemmed Acute schistosomiasis: clinical, diagnostic and therapeutic features
title_sort Acute schistosomiasis: clinical, diagnostic and therapeutic features
author Lambertucci, J. R.
author_facet Lambertucci, J. R.
author_role author
dc.contributor.author.fl_str_mv Lambertucci, J. R.
dc.subject.por.fl_str_mv Acute schistosomiasis
Oxamniquine
Praziquantel
Corticosteroids
topic Acute schistosomiasis
Oxamniquine
Praziquantel
Corticosteroids
description Three distinct syndromes caused by schistosomiasis have been described: cercarial dermatitis or swimmer's itch, acute schistosomiasis or Katayama fever, and chronic schistosomiasis. Complications of acute schistosomiasis have also been reported. The absence of a serological marker for the acute stage has hindered early diagnosis and treatment. Recently, an ELISA test using KLH (keyhole limpet haemocyanin) as antigen, has proved useful in differentiating acute from chronic schistosomiasis mansoni. Clinical and experimental evidence indicate that steroids act synergistically with schistosomicides in the treatment of Katayama syndrome. In this paper, clinical, diagnostic and therapeutic features of acute schistosomiasis are updated.
publishDate 1993
dc.date.none.fl_str_mv 1993-10-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.revistas.usp.br/rimtsp/article/view/29076
url https://www.revistas.usp.br/rimtsp/article/view/29076
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://www.revistas.usp.br/rimtsp/article/view/29076/30933
dc.rights.driver.fl_str_mv Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Paulo
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Paulo
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo
publisher.none.fl_str_mv Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo
dc.source.none.fl_str_mv Revista do Instituto de Medicina Tropical de São Paulo; Vol. 35 No. 5 (1993); 399-404
Revista do Instituto de Medicina Tropical de São Paulo; Vol. 35 Núm. 5 (1993); 399-404
Revista do Instituto de Medicina Tropical de São Paulo; v. 35 n. 5 (1993); 399-404
1678-9946
0036-4665
reponame:Revista do Instituto de Medicina Tropical de São Paulo
instname:Instituto de Medicina Tropical (IMT)
instacron:IMT
instname_str Instituto de Medicina Tropical (IMT)
instacron_str IMT
institution IMT
reponame_str Revista do Instituto de Medicina Tropical de São Paulo
collection Revista do Instituto de Medicina Tropical de São Paulo
repository.name.fl_str_mv Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT)
repository.mail.fl_str_mv ||revimtsp@usp.br
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