Study of chronic hemolytic anaemia patients in Rio de Janeiro: prevalence of anti-human parvovirus B19 IgG antibodies and the developement aplastic crises
Autor(a) principal: | |
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Data de Publicação: | 2002 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Revista do Instituto de Medicina Tropical de São Paulo |
Texto Completo: | https://www.revistas.usp.br/rimtsp/article/view/30621 |
Resumo: | The prevalence of anti-human parvovirus B19 IgG antibodies was determined in sera from 165 chronic hemolytic anemia patients, receiving medical care at Instituto Estadual de Hematologia (IEHE), Rio de Janeiro, during the year of 1994. This sample represents around 10% of the chronic hemolytic anemia patients attending at IEHE. Most of these patients (140) have sickle cell disease. Anti-B19 IgG antibodies were detected in 32.1% of patients. No statistically significant difference (p >; 0.05) was seen between IgG antibody prevalence in male (27.8%) and female (35.5%) patients. Anti-B19 IgG antibodies were more frequent in older (37.6%) than younger (28.2%) than 20 years old patients, although this difference had no statistical significance (p >; 0.05). Anti-B19 IgG antibody prevalence showed that 67.9% of patients enrolled in the study were susceptible to B19 acute infection. With the aim to detect acute B19 infection, patients follow up continued until February 1996. During this period four patients presented transient aplastic crisis due to human parvovirus B19 as confirmed by the detection of specific IgM antibodies. All four patients were younger than 20 years old, and 3 were younger than 10 years old. Three of them were sickle cell disease patients. Three of the four acute B19 infection occurred during 1994 springtime. |
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Study of chronic hemolytic anaemia patients in Rio de Janeiro: prevalence of anti-human parvovirus B19 IgG antibodies and the developement aplastic crises Estudo de pacientes com anemia hemolítica crônica no Rio de Janeiro: prevalência de anticorpos IgG anti-parvovirus humano B19 e desenvolvimento de crise aplástica transitória Human Parvovirus B19Sickle-cell diseaseTransient aplastic crisis The prevalence of anti-human parvovirus B19 IgG antibodies was determined in sera from 165 chronic hemolytic anemia patients, receiving medical care at Instituto Estadual de Hematologia (IEHE), Rio de Janeiro, during the year of 1994. This sample represents around 10% of the chronic hemolytic anemia patients attending at IEHE. Most of these patients (140) have sickle cell disease. Anti-B19 IgG antibodies were detected in 32.1% of patients. No statistically significant difference (p >; 0.05) was seen between IgG antibody prevalence in male (27.8%) and female (35.5%) patients. Anti-B19 IgG antibodies were more frequent in older (37.6%) than younger (28.2%) than 20 years old patients, although this difference had no statistical significance (p >; 0.05). Anti-B19 IgG antibody prevalence showed that 67.9% of patients enrolled in the study were susceptible to B19 acute infection. With the aim to detect acute B19 infection, patients follow up continued until February 1996. During this period four patients presented transient aplastic crisis due to human parvovirus B19 as confirmed by the detection of specific IgM antibodies. All four patients were younger than 20 years old, and 3 were younger than 10 years old. Three of them were sickle cell disease patients. Three of the four acute B19 infection occurred during 1994 springtime. A prevalência de anticorpos anti-parvovirus humano B19 foi determinada em soros de 165 pacientes portadores de anemia hemolítica crônica, atendidos no Instituto Estadual de Hematologia (IEHE), Rio de Janeiro, durante o ano de 1994. Esta amostra representa cerca de 10% dos pacientes portadores de anemia hemolítica crônica atendidos no IEHE. A maioria destes pacientes (140) são portadores de anemia falciforme. Anticorpos IgG anti-parvovirus humano B19 foram detectados em 32,1% dos pacientes. Nenhuma diferença estatisticamente significante foi verificada entre a prevalência de anticorpos em pacientes do sexo masculino (27,8%) e feminino (35,5%). Anticorpos IgG anti-parvovirus humano B19 foram mais freqüentes em pacientes na faixa etária acima (37,8%) que abaixo (28,2%) de 20 anos de idade, embora esta diferença não tenha significado estatístico (p >; 0,05). A prevalência de anticorpos IgG anti-B19 demonstrou que 67,9% dos pacientes incluídos no estudo eram ainda suscetíveis à infecção aguda pelo parvovirus humano B19. Com o objetivo de detectar infecção aguda por este vírus, o seguimento de pacientes continuou até fevereiro de 1996. Durante este período, 4 pacientes apresentaram crise de aplasia transitória devido ao parvovirus humano B19 conforme confirmado pela detecção de anticorpos IgM específicos. Todos 4 pacientes estavam na faixa etária abaixo de 20 anos, sendo que 3 tinham menos de 10 anos de idade. Três destes pacientes eram portadores de anemia falciforme. Em 3 dos 4 pacientes, a infecção aguda por B19 ocorreu durante a primavera de 1994. Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo2002-07-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/rimtsp/article/view/30621Revista do Instituto de Medicina Tropical de São Paulo; Vol. 44 No. 4 (2002); 187-190 Revista do Instituto de Medicina Tropical de São Paulo; Vol. 44 Núm. 4 (2002); 187-190 Revista do Instituto de Medicina Tropical de São Paulo; v. 44 n. 4 (2002); 187-190 1678-99460036-4665reponame:Revista do Instituto de Medicina Tropical de São Pauloinstname:Instituto de Medicina Tropical (IMT)instacron:IMTenghttps://www.revistas.usp.br/rimtsp/article/view/30621/32505Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Pauloinfo:eu-repo/semantics/openAccessSANT'ANNA, Anadayr L.M.GARCIA, Rita de Cássia N. CubelMARZOCHE, MônicaROCHA, Heloisa Helena A. Gallo daPAULA, Maria Tereza M.LOBO, Clarisse C.NASCIMENTO, Jussara P.2012-07-07T17:51:54Zoai:revistas.usp.br:article/30621Revistahttp://www.revistas.usp.br/rimtsp/indexPUBhttps://www.revistas.usp.br/rimtsp/oai||revimtsp@usp.br1678-99460036-4665opendoar:2022-12-13T16:51:23.919751Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT)true |
dc.title.none.fl_str_mv |
Study of chronic hemolytic anaemia patients in Rio de Janeiro: prevalence of anti-human parvovirus B19 IgG antibodies and the developement aplastic crises Estudo de pacientes com anemia hemolítica crônica no Rio de Janeiro: prevalência de anticorpos IgG anti-parvovirus humano B19 e desenvolvimento de crise aplástica transitória |
title |
Study of chronic hemolytic anaemia patients in Rio de Janeiro: prevalence of anti-human parvovirus B19 IgG antibodies and the developement aplastic crises |
spellingShingle |
Study of chronic hemolytic anaemia patients in Rio de Janeiro: prevalence of anti-human parvovirus B19 IgG antibodies and the developement aplastic crises SANT'ANNA, Anadayr L.M. Human Parvovirus B19 Sickle-cell disease Transient aplastic crisis |
title_short |
Study of chronic hemolytic anaemia patients in Rio de Janeiro: prevalence of anti-human parvovirus B19 IgG antibodies and the developement aplastic crises |
title_full |
Study of chronic hemolytic anaemia patients in Rio de Janeiro: prevalence of anti-human parvovirus B19 IgG antibodies and the developement aplastic crises |
title_fullStr |
Study of chronic hemolytic anaemia patients in Rio de Janeiro: prevalence of anti-human parvovirus B19 IgG antibodies and the developement aplastic crises |
title_full_unstemmed |
Study of chronic hemolytic anaemia patients in Rio de Janeiro: prevalence of anti-human parvovirus B19 IgG antibodies and the developement aplastic crises |
title_sort |
Study of chronic hemolytic anaemia patients in Rio de Janeiro: prevalence of anti-human parvovirus B19 IgG antibodies and the developement aplastic crises |
author |
SANT'ANNA, Anadayr L.M. |
author_facet |
SANT'ANNA, Anadayr L.M. GARCIA, Rita de Cássia N. Cubel MARZOCHE, Mônica ROCHA, Heloisa Helena A. Gallo da PAULA, Maria Tereza M. LOBO, Clarisse C. NASCIMENTO, Jussara P. |
author_role |
author |
author2 |
GARCIA, Rita de Cássia N. Cubel MARZOCHE, Mônica ROCHA, Heloisa Helena A. Gallo da PAULA, Maria Tereza M. LOBO, Clarisse C. NASCIMENTO, Jussara P. |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
SANT'ANNA, Anadayr L.M. GARCIA, Rita de Cássia N. Cubel MARZOCHE, Mônica ROCHA, Heloisa Helena A. Gallo da PAULA, Maria Tereza M. LOBO, Clarisse C. NASCIMENTO, Jussara P. |
dc.subject.por.fl_str_mv |
Human Parvovirus B19 Sickle-cell disease Transient aplastic crisis |
topic |
Human Parvovirus B19 Sickle-cell disease Transient aplastic crisis |
description |
The prevalence of anti-human parvovirus B19 IgG antibodies was determined in sera from 165 chronic hemolytic anemia patients, receiving medical care at Instituto Estadual de Hematologia (IEHE), Rio de Janeiro, during the year of 1994. This sample represents around 10% of the chronic hemolytic anemia patients attending at IEHE. Most of these patients (140) have sickle cell disease. Anti-B19 IgG antibodies were detected in 32.1% of patients. No statistically significant difference (p >; 0.05) was seen between IgG antibody prevalence in male (27.8%) and female (35.5%) patients. Anti-B19 IgG antibodies were more frequent in older (37.6%) than younger (28.2%) than 20 years old patients, although this difference had no statistical significance (p >; 0.05). Anti-B19 IgG antibody prevalence showed that 67.9% of patients enrolled in the study were susceptible to B19 acute infection. With the aim to detect acute B19 infection, patients follow up continued until February 1996. During this period four patients presented transient aplastic crisis due to human parvovirus B19 as confirmed by the detection of specific IgM antibodies. All four patients were younger than 20 years old, and 3 were younger than 10 years old. Three of them were sickle cell disease patients. Three of the four acute B19 infection occurred during 1994 springtime. |
publishDate |
2002 |
dc.date.none.fl_str_mv |
2002-07-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.revistas.usp.br/rimtsp/article/view/30621 |
url |
https://www.revistas.usp.br/rimtsp/article/view/30621 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://www.revistas.usp.br/rimtsp/article/view/30621/32505 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Paulo info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Paulo |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo |
publisher.none.fl_str_mv |
Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo |
dc.source.none.fl_str_mv |
Revista do Instituto de Medicina Tropical de São Paulo; Vol. 44 No. 4 (2002); 187-190 Revista do Instituto de Medicina Tropical de São Paulo; Vol. 44 Núm. 4 (2002); 187-190 Revista do Instituto de Medicina Tropical de São Paulo; v. 44 n. 4 (2002); 187-190 1678-9946 0036-4665 reponame:Revista do Instituto de Medicina Tropical de São Paulo instname:Instituto de Medicina Tropical (IMT) instacron:IMT |
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Instituto de Medicina Tropical (IMT) |
instacron_str |
IMT |
institution |
IMT |
reponame_str |
Revista do Instituto de Medicina Tropical de São Paulo |
collection |
Revista do Instituto de Medicina Tropical de São Paulo |
repository.name.fl_str_mv |
Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT) |
repository.mail.fl_str_mv |
||revimtsp@usp.br |
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1798951643443625984 |