Biological implications of the phenotypic plasticity in the Schistosoma mansoni - Nectomys squamipes model

Detalhes bibliográficos
Autor(a) principal: Martinez, Elaine Machado
Data de Publicação: 2008
Outros Autores: Costa-Silva, Michele, Neves, Renata Heisler, Oliveira, Regina Maria Figueiredo de, Machado-Silva, José Roberto
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista do Instituto de Medicina Tropical de São Paulo
Texto Completo: https://www.revistas.usp.br/rimtsp/article/view/31191
Resumo: The water-rat Nectomys squamipes is mostly important non-human host in schistosomiasis mansoni transmission in Brazil, due to its susceptibility, high abundance and water-contact pattern. During experimental infection of N. squamipes with Schistosoma mansoni, adult worms show phenotypic plasticity. This finding led us to investigate whether biological behavior is also affected. This was assessed comparing the biological characteristics of four S. mansoni strains: BE (State of Belém do Pará), CE (State of Pernambuco), CMO (State of Rio Grande do Norte) and SJ (State of São Paulo) using laboratory-bred N. squamipes. The infection was monitored by determination of the pre-patent period, fecal egg output, egg viability, intestinal egg count and, infectivity rate. No biological modification was observed in these parameters. Overall results highlight that N. squamipes was susceptible to several S. mansoni strains, suggesting that it might contribute to the maintenance of schistosomiasis mansoni in Brazil.
id IMT-1_13869b405b1f02b90f7f75521e15bea1
oai_identifier_str oai:revistas.usp.br:article/31191
network_acronym_str IMT-1
network_name_str Revista do Instituto de Medicina Tropical de São Paulo
repository_id_str
spelling Biological implications of the phenotypic plasticity in the Schistosoma mansoni - Nectomys squamipes model Implicações biológicas da plasticidade fenotípica no modelo Schistosoma mansoni - Nectomys squamipes Schistosoma mansoniNectomys squamipesEpidemiologyBiological study The water-rat Nectomys squamipes is mostly important non-human host in schistosomiasis mansoni transmission in Brazil, due to its susceptibility, high abundance and water-contact pattern. During experimental infection of N. squamipes with Schistosoma mansoni, adult worms show phenotypic plasticity. This finding led us to investigate whether biological behavior is also affected. This was assessed comparing the biological characteristics of four S. mansoni strains: BE (State of Belém do Pará), CE (State of Pernambuco), CMO (State of Rio Grande do Norte) and SJ (State of São Paulo) using laboratory-bred N. squamipes. The infection was monitored by determination of the pre-patent period, fecal egg output, egg viability, intestinal egg count and, infectivity rate. No biological modification was observed in these parameters. Overall results highlight that N. squamipes was susceptible to several S. mansoni strains, suggesting that it might contribute to the maintenance of schistosomiasis mansoni in Brazil. O rato d´água Nectomys squamipes é importante transmissor não-humano da esquistossomose. Durante a infecção experimental em N. squamipes, os vermes adultos apresentam plasticidade fenotípica. Esses achados levaram-nos a investigar se os aspectos biológicos também são afetados. Foram comparadas as características biológicas de quatro cepas de S. mansoni: BE (Estado de Belém do Pará), CM (Estado de Pernambuco), CMO (Estado do Rio Grande do Norte) e SJ (Estado de São Paulo), utilizando como modelo experimental N. squamipes criados e mantidos em laboratório. A infecção foi monitorada para a determinação do período pré-patente, eliminação de ovos nas fezes, viabilidade dos ovos, contagem de ovos retidos no intestino e infectividade. Nenhuma modificação biológica foi observada nesses parâmetros. Os resultados sugerem que o N. squamipes é susceptível a várias cepas de S. mansoni, contribuindo para a manutenção da esquistossomose no Brasil. Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo2008-08-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/rimtsp/article/view/31191Revista do Instituto de Medicina Tropical de São Paulo; Vol. 50 No. 4 (2008); 229-232 Revista do Instituto de Medicina Tropical de São Paulo; Vol. 50 Núm. 4 (2008); 229-232 Revista do Instituto de Medicina Tropical de São Paulo; v. 50 n. 4 (2008); 229-232 1678-99460036-4665reponame:Revista do Instituto de Medicina Tropical de São Pauloinstname:Instituto de Medicina Tropical (IMT)instacron:IMTenghttps://www.revistas.usp.br/rimtsp/article/view/31191/33075Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Pauloinfo:eu-repo/semantics/openAccessMartinez, Elaine MachadoCosta-Silva, MicheleNeves, Renata HeislerOliveira, Regina Maria Figueiredo deMachado-Silva, José Roberto2012-07-07T19:10:15Zoai:revistas.usp.br:article/31191Revistahttp://www.revistas.usp.br/rimtsp/indexPUBhttps://www.revistas.usp.br/rimtsp/oai||revimtsp@usp.br1678-99460036-4665opendoar:2022-12-13T16:51:52.690728Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT)true
dc.title.none.fl_str_mv Biological implications of the phenotypic plasticity in the Schistosoma mansoni - Nectomys squamipes model
Implicações biológicas da plasticidade fenotípica no modelo Schistosoma mansoni - Nectomys squamipes
title Biological implications of the phenotypic plasticity in the Schistosoma mansoni - Nectomys squamipes model
spellingShingle Biological implications of the phenotypic plasticity in the Schistosoma mansoni - Nectomys squamipes model
Martinez, Elaine Machado
Schistosoma mansoni
Nectomys squamipes
Epidemiology
Biological study
title_short Biological implications of the phenotypic plasticity in the Schistosoma mansoni - Nectomys squamipes model
title_full Biological implications of the phenotypic plasticity in the Schistosoma mansoni - Nectomys squamipes model
title_fullStr Biological implications of the phenotypic plasticity in the Schistosoma mansoni - Nectomys squamipes model
title_full_unstemmed Biological implications of the phenotypic plasticity in the Schistosoma mansoni - Nectomys squamipes model
title_sort Biological implications of the phenotypic plasticity in the Schistosoma mansoni - Nectomys squamipes model
author Martinez, Elaine Machado
author_facet Martinez, Elaine Machado
Costa-Silva, Michele
Neves, Renata Heisler
Oliveira, Regina Maria Figueiredo de
Machado-Silva, José Roberto
author_role author
author2 Costa-Silva, Michele
Neves, Renata Heisler
Oliveira, Regina Maria Figueiredo de
Machado-Silva, José Roberto
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Martinez, Elaine Machado
Costa-Silva, Michele
Neves, Renata Heisler
Oliveira, Regina Maria Figueiredo de
Machado-Silva, José Roberto
dc.subject.por.fl_str_mv Schistosoma mansoni
Nectomys squamipes
Epidemiology
Biological study
topic Schistosoma mansoni
Nectomys squamipes
Epidemiology
Biological study
description The water-rat Nectomys squamipes is mostly important non-human host in schistosomiasis mansoni transmission in Brazil, due to its susceptibility, high abundance and water-contact pattern. During experimental infection of N. squamipes with Schistosoma mansoni, adult worms show phenotypic plasticity. This finding led us to investigate whether biological behavior is also affected. This was assessed comparing the biological characteristics of four S. mansoni strains: BE (State of Belém do Pará), CE (State of Pernambuco), CMO (State of Rio Grande do Norte) and SJ (State of São Paulo) using laboratory-bred N. squamipes. The infection was monitored by determination of the pre-patent period, fecal egg output, egg viability, intestinal egg count and, infectivity rate. No biological modification was observed in these parameters. Overall results highlight that N. squamipes was susceptible to several S. mansoni strains, suggesting that it might contribute to the maintenance of schistosomiasis mansoni in Brazil.
publishDate 2008
dc.date.none.fl_str_mv 2008-08-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.revistas.usp.br/rimtsp/article/view/31191
url https://www.revistas.usp.br/rimtsp/article/view/31191
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://www.revistas.usp.br/rimtsp/article/view/31191/33075
dc.rights.driver.fl_str_mv Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Paulo
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Paulo
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo
publisher.none.fl_str_mv Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo
dc.source.none.fl_str_mv Revista do Instituto de Medicina Tropical de São Paulo; Vol. 50 No. 4 (2008); 229-232
Revista do Instituto de Medicina Tropical de São Paulo; Vol. 50 Núm. 4 (2008); 229-232
Revista do Instituto de Medicina Tropical de São Paulo; v. 50 n. 4 (2008); 229-232
1678-9946
0036-4665
reponame:Revista do Instituto de Medicina Tropical de São Paulo
instname:Instituto de Medicina Tropical (IMT)
instacron:IMT
instname_str Instituto de Medicina Tropical (IMT)
instacron_str IMT
institution IMT
reponame_str Revista do Instituto de Medicina Tropical de São Paulo
collection Revista do Instituto de Medicina Tropical de São Paulo
repository.name.fl_str_mv Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT)
repository.mail.fl_str_mv ||revimtsp@usp.br
_version_ 1798951646893441024

Registros relacionados