Fungal infections in neutropenic patients: a 8-year prospective study

• Autor(a) principal: Nucci, Marcio
• Data de Publicação: 1995
• Outros Autores: Pulcheri, Wolmar, Spector, Nelson, Bueno, Ana Paula, Bacha, Paulo Cesar, Caiuby, Maria Julieta, Derossi, Andrea, Costa, Rosane, Morals, José Carlos, Oliveira, Halley Pacheco de
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Revista do Instituto de Medicina Tropical de São Paulo
• Texto Completo: https://www.revistas.usp.br/rimtsp/article/view/29299
• topic: Aspergillosis; Fusarium sp. infections; Candidiasis; Trichosporon sp. infections; Opportunistic fungal infections

In this paper we report a eight-year prospective study designed to further characterize incidence, epidemiology, specific syndromes, treatment and prognosis associated with fungal infections in neutropenic patients. During the study period 30 fungal infections were diagnosed in 30 patients among 313 episodes of fever and neutropenia (10%). There were 15 cases of candidiasis, 5 pulmonary aspergillosis, 3 sinusitis by Aspergillus fumigatus, 5 infections by Fusarium sp., one infection by Trichosporon sp., and one infection due to Rhodotorula rubra. Blood cultures were positive in 18 cases (60%). The predisposing factors for fungal infection in multivariate analysis were the presence of central venous catheter (p