Adverse effect of the intermittent use of rifampin tor leprosy treatment

Detalhes bibliográficos
Autor(a) principal: Papaiordanou, Priscila Maria de Oliveira
Data de Publicação: 1988
Outros Autores: Branchini, Maria Luiza Moretti, Gonçales Júnior, Fernando Lopes, Aoki, Francisco Hideo, Boccato, Raquel Silveira Bello Stucchi, Ramos, Marcelo de Carvalho, Pedro, Rogério de Jesus
Tipo de documento: Artigo
Idioma: por
Título da fonte: Revista do Instituto de Medicina Tropical de São Paulo
Texto Completo: https://www.revistas.usp.br/rimtsp/article/view/28613
Resumo: The authors present a case of acute renal failure, acute hemolysis and thrombocytopenia due to intermittent use of Rifampin for leprosy. These adverse reactions have rarely been discribed in the medical literature. During follow up there was recovery of renal function and complete remission of the hematological alterations. To our knowledge, this has been the first report of such adverse effects of Rifampin during leprosy therapy in Brazil. Pathogenetic aspects are discussed and current literature is reviewed.
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spelling Adverse effect of the intermittent use of rifampin tor leprosy treatment Efeito adverso do uso intermitente de rifampicina para tratamento de hanseníase Insuficiência renal agudaHemólise agudaTrombocitopeniaHanseníase The authors present a case of acute renal failure, acute hemolysis and thrombocytopenia due to intermittent use of Rifampin for leprosy. These adverse reactions have rarely been discribed in the medical literature. During follow up there was recovery of renal function and complete remission of the hematological alterations. To our knowledge, this has been the first report of such adverse effects of Rifampin during leprosy therapy in Brazil. Pathogenetic aspects are discussed and current literature is reviewed. Os autores apresentam um caso de insuficiência renal aguda, hemólise aguda e trombocitopenia relacionada ao uso intermitente de Rifampicina para tratamento da Hanseníase. Estas reações adversas são observadas com extrema raridade na literatura mundial. A evolução da paciente foi benigna havendo recuperação total da função renal e regressão completa das alterações hematológicas. Este foi o primeiro registro no Brasil dos efeitos adversos da Rifampicina no tratamento de Hanseníase. São discutidos os principais aspectos patogênicos das alterações apresentadas e fez-se revisão da literatura existente sobre o assunto. Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo1988-10-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/rimtsp/article/view/28613Revista do Instituto de Medicina Tropical de São Paulo; Vol. 30 No. 5 (1988); 383-386 Revista do Instituto de Medicina Tropical de São Paulo; Vol. 30 Núm. 5 (1988); 383-386 Revista do Instituto de Medicina Tropical de São Paulo; v. 30 n. 5 (1988); 383-386 1678-99460036-4665reponame:Revista do Instituto de Medicina Tropical de São Pauloinstname:Instituto de Medicina Tropical (IMT)instacron:IMTporhttps://www.revistas.usp.br/rimtsp/article/view/28613/30466Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Pauloinfo:eu-repo/semantics/openAccessPapaiordanou, Priscila Maria de OliveiraBranchini, Maria Luiza MorettiGonçales Júnior, Fernando LopesAoki, Francisco HideoBoccato, Raquel Silveira Bello StucchiRamos, Marcelo de CarvalhoPedro, Rogério de Jesus2012-07-02T01:06:59Zoai:revistas.usp.br:article/28613Revistahttp://www.revistas.usp.br/rimtsp/indexPUBhttps://www.revistas.usp.br/rimtsp/oai||revimtsp@usp.br1678-99460036-4665opendoar:2022-12-13T16:50:21.351587Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT)true
dc.title.none.fl_str_mv Adverse effect of the intermittent use of rifampin tor leprosy treatment
Efeito adverso do uso intermitente de rifampicina para tratamento de hanseníase
title Adverse effect of the intermittent use of rifampin tor leprosy treatment
spellingShingle Adverse effect of the intermittent use of rifampin tor leprosy treatment
Papaiordanou, Priscila Maria de Oliveira
Insuficiência renal aguda
Hemólise aguda
Trombocitopenia
Hanseníase
title_short Adverse effect of the intermittent use of rifampin tor leprosy treatment
title_full Adverse effect of the intermittent use of rifampin tor leprosy treatment
title_fullStr Adverse effect of the intermittent use of rifampin tor leprosy treatment
title_full_unstemmed Adverse effect of the intermittent use of rifampin tor leprosy treatment
title_sort Adverse effect of the intermittent use of rifampin tor leprosy treatment
author Papaiordanou, Priscila Maria de Oliveira
author_facet Papaiordanou, Priscila Maria de Oliveira
Branchini, Maria Luiza Moretti
Gonçales Júnior, Fernando Lopes
Aoki, Francisco Hideo
Boccato, Raquel Silveira Bello Stucchi
Ramos, Marcelo de Carvalho
Pedro, Rogério de Jesus
author_role author
author2 Branchini, Maria Luiza Moretti
Gonçales Júnior, Fernando Lopes
Aoki, Francisco Hideo
Boccato, Raquel Silveira Bello Stucchi
Ramos, Marcelo de Carvalho
Pedro, Rogério de Jesus
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Papaiordanou, Priscila Maria de Oliveira
Branchini, Maria Luiza Moretti
Gonçales Júnior, Fernando Lopes
Aoki, Francisco Hideo
Boccato, Raquel Silveira Bello Stucchi
Ramos, Marcelo de Carvalho
Pedro, Rogério de Jesus
dc.subject.por.fl_str_mv Insuficiência renal aguda
Hemólise aguda
Trombocitopenia
Hanseníase
topic Insuficiência renal aguda
Hemólise aguda
Trombocitopenia
Hanseníase
description The authors present a case of acute renal failure, acute hemolysis and thrombocytopenia due to intermittent use of Rifampin for leprosy. These adverse reactions have rarely been discribed in the medical literature. During follow up there was recovery of renal function and complete remission of the hematological alterations. To our knowledge, this has been the first report of such adverse effects of Rifampin during leprosy therapy in Brazil. Pathogenetic aspects are discussed and current literature is reviewed.
publishDate 1988
dc.date.none.fl_str_mv 1988-10-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.revistas.usp.br/rimtsp/article/view/28613
url https://www.revistas.usp.br/rimtsp/article/view/28613
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://www.revistas.usp.br/rimtsp/article/view/28613/30466
dc.rights.driver.fl_str_mv Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Paulo
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Paulo
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo
publisher.none.fl_str_mv Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo
dc.source.none.fl_str_mv Revista do Instituto de Medicina Tropical de São Paulo; Vol. 30 No. 5 (1988); 383-386
Revista do Instituto de Medicina Tropical de São Paulo; Vol. 30 Núm. 5 (1988); 383-386
Revista do Instituto de Medicina Tropical de São Paulo; v. 30 n. 5 (1988); 383-386
1678-9946
0036-4665
reponame:Revista do Instituto de Medicina Tropical de São Paulo
instname:Instituto de Medicina Tropical (IMT)
instacron:IMT
instname_str Instituto de Medicina Tropical (IMT)
instacron_str IMT
institution IMT
reponame_str Revista do Instituto de Medicina Tropical de São Paulo
collection Revista do Instituto de Medicina Tropical de São Paulo
repository.name.fl_str_mv Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT)
repository.mail.fl_str_mv ||revimtsp@usp.br
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