Cirurgia Conservadora e Radioterapia no Tratamento do Câncer da Mama

Detalhes bibliográficos
Autor(a) principal: Souhami, Luis
Data de Publicação: 2023
Outros Autores: Carvalho Filho, Jurandir P., Guizzardi, Miguel F.
Tipo de documento: Artigo
Idioma: por
Título da fonte: Revista Brasileira de Cancerologia (Online)
Texto Completo: https://rbc.inca.gov.br/index.php/revista/article/view/3358
Resumo: From January of 1973 to December of 1983, 59 patients with breast cancer, treated conservatively by surgery, were refered to radiotherapy at the Instituto Nacional de Câncer. The mean age was 53 years (range: 24-83 years) and 50% of the patients were pre-menopausal. The clinical staging revealed 13 patients with T1 tumors, 34 with T2 tumors and three with T3 tumors. In nine patients this information was not available. The axilla was clinically involved in 10 cases and was surgically staged in 29 patients with a mean number of 14,2 lymphnodes removed (range: 2-36). The clinical/surgical correlation was 63%. Following tumorectomy (56% of the cases), quadrantectomy (39%) or biopsy only (3%), patients received radiotherapy to the breast with 5000 cGy being delivered. A boost dose of 1000-2000 cGy to the tumor bed followed the primary treatment. All patients were treated with cobalt therapy and electrons (boost dose). The lymphatics were irradiated in 48% of the cases. The overall survival rate at 5 years was 78% with 65% of the patients surviving free of disease (locally and distantly) at the same period. Four patients (7%) failed in the breast, three (5%) in the axiliar lymphnodes and nine (15%) distantly. The cosmetic results were considered excellent and good in 60% of the cases and this was most frequently observed in those patients treated by tumorectomy. The conservative treatment of breast cancer seems to be an acceptable option to this pathology. It offers to the patient an extremely satisfactory cosmetic result while keeping surviva! and local control similar to most mutilating treatments.
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spelling Cirurgia Conservadora e Radioterapia no Tratamento do Câncer da MamaCâncer da MamaTratamento ConservadorRadioterapiaBreast CancerConservative TreatmentRadiotherapyFrom January of 1973 to December of 1983, 59 patients with breast cancer, treated conservatively by surgery, were refered to radiotherapy at the Instituto Nacional de Câncer. The mean age was 53 years (range: 24-83 years) and 50% of the patients were pre-menopausal. The clinical staging revealed 13 patients with T1 tumors, 34 with T2 tumors and three with T3 tumors. In nine patients this information was not available. The axilla was clinically involved in 10 cases and was surgically staged in 29 patients with a mean number of 14,2 lymphnodes removed (range: 2-36). The clinical/surgical correlation was 63%. Following tumorectomy (56% of the cases), quadrantectomy (39%) or biopsy only (3%), patients received radiotherapy to the breast with 5000 cGy being delivered. A boost dose of 1000-2000 cGy to the tumor bed followed the primary treatment. All patients were treated with cobalt therapy and electrons (boost dose). The lymphatics were irradiated in 48% of the cases. The overall survival rate at 5 years was 78% with 65% of the patients surviving free of disease (locally and distantly) at the same period. Four patients (7%) failed in the breast, three (5%) in the axiliar lymphnodes and nine (15%) distantly. The cosmetic results were considered excellent and good in 60% of the cases and this was most frequently observed in those patients treated by tumorectomy. The conservative treatment of breast cancer seems to be an acceptable option to this pathology. It offers to the patient an extremely satisfactory cosmetic result while keeping surviva! and local control similar to most mutilating treatments.No período de janeiro de 1973 a dezembro de 1983, 59 pacientes com carcinoma da mama, tratadas conservadoramente, foram encaminhadas ao serviço de radioterapia do Instituto Nacional de Câncer. A idade média do grupo foi de 53 anos (variação: 24 a 83 anos), com 50% das pacientes em pré-menopausa. O estadiamento clínico revelou 13 pacientes com tumores TI, 34 com tumores T2 e três com tumores T3. Em nove pacientes essa informação não pôde ser obtida. A axila estava clinicamente positiva em 10 casos e foi cirurgicamente estadiada em 29 pacientes com um número médio de linfonodos retirados de 14,2 (variação: 2-36). A correlação clínica/cirúrgica foi de 63%. Após tumorectomia (56% das pacientes), quadrantectomia (39%). ou biópsia (3%). As pacientes eram submetidas à irradiação de todo o parênquima mamário com dose de 5000 cGy seguida de reforço sobre o leito tumoral (1000-2000 cGy). Todas as pacientes foram tratadas com cobaltoterapia e elétrons. As cadeias linfáticas foram irradiadas em 48% dos casos. A sobrevida aos 5 anos foi de 78% com 64% das pacientes sobrevivendo livre de doença (local e a distância) ao término desse período. Quatro pacientes (7%) falharam na mama, três (5%) na axila e nove (15%) a distância. O resultado cosmético foi considerado excelente e bom em 60% dos casos e isso foi observado mais frequentemente nas pacientes tratadas com tumorectomia. O tratamento conservador do câncer da mama parece ser uma opção aceitável de tratamento para essa patologia. A não mutilação do órgão não altera os resultados e oferece à paciente um resultado cosmético extremamente satisfatório.INCA2023-08-07info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArtigos, Avaliado pelos paresapplication/pdfhttps://rbc.inca.gov.br/index.php/revista/article/view/335810.32635/2176-9745.RBC.1985v31n4.3358Revista Brasileira de Cancerologia; Vol. 31 No. 4 (1985): Dec.; 243-248Revista Brasileira de Cancerologia; Vol. 31 Núm. 4 (1985): dic.; 243-248Revista Brasileira de Cancerologia; v. 31 n. 4 (1985): dez.; 243-2482176-9745reponame:Revista Brasileira de Cancerologia (Online)instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)instacron:INCAporhttps://rbc.inca.gov.br/index.php/revista/article/view/3358/2196https://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessSouhami, LuisCarvalho Filho, Jurandir P.Guizzardi, Miguel F.2023-08-07T20:41:53Zoai:rbc.inca.gov.br:article/3358Revistahttps://rbc.inca.gov.br/index.php/revistaPUBhttps://rbc.inca.gov.br/index.php/revista/oairbc@inca.gov.br0034-71162176-9745opendoar:2023-08-07T20:41:53Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)false
dc.title.none.fl_str_mv Cirurgia Conservadora e Radioterapia no Tratamento do Câncer da Mama
title Cirurgia Conservadora e Radioterapia no Tratamento do Câncer da Mama
spellingShingle Cirurgia Conservadora e Radioterapia no Tratamento do Câncer da Mama
Souhami, Luis
Câncer da Mama
Tratamento Conservador
Radioterapia
Breast Cancer
Conservative Treatment
Radiotherapy
title_short Cirurgia Conservadora e Radioterapia no Tratamento do Câncer da Mama
title_full Cirurgia Conservadora e Radioterapia no Tratamento do Câncer da Mama
title_fullStr Cirurgia Conservadora e Radioterapia no Tratamento do Câncer da Mama
title_full_unstemmed Cirurgia Conservadora e Radioterapia no Tratamento do Câncer da Mama
title_sort Cirurgia Conservadora e Radioterapia no Tratamento do Câncer da Mama
author Souhami, Luis
author_facet Souhami, Luis
Carvalho Filho, Jurandir P.
Guizzardi, Miguel F.
author_role author
author2 Carvalho Filho, Jurandir P.
Guizzardi, Miguel F.
author2_role author
author
dc.contributor.author.fl_str_mv Souhami, Luis
Carvalho Filho, Jurandir P.
Guizzardi, Miguel F.
dc.subject.por.fl_str_mv Câncer da Mama
Tratamento Conservador
Radioterapia
Breast Cancer
Conservative Treatment
Radiotherapy
topic Câncer da Mama
Tratamento Conservador
Radioterapia
Breast Cancer
Conservative Treatment
Radiotherapy
description From January of 1973 to December of 1983, 59 patients with breast cancer, treated conservatively by surgery, were refered to radiotherapy at the Instituto Nacional de Câncer. The mean age was 53 years (range: 24-83 years) and 50% of the patients were pre-menopausal. The clinical staging revealed 13 patients with T1 tumors, 34 with T2 tumors and three with T3 tumors. In nine patients this information was not available. The axilla was clinically involved in 10 cases and was surgically staged in 29 patients with a mean number of 14,2 lymphnodes removed (range: 2-36). The clinical/surgical correlation was 63%. Following tumorectomy (56% of the cases), quadrantectomy (39%) or biopsy only (3%), patients received radiotherapy to the breast with 5000 cGy being delivered. A boost dose of 1000-2000 cGy to the tumor bed followed the primary treatment. All patients were treated with cobalt therapy and electrons (boost dose). The lymphatics were irradiated in 48% of the cases. The overall survival rate at 5 years was 78% with 65% of the patients surviving free of disease (locally and distantly) at the same period. Four patients (7%) failed in the breast, three (5%) in the axiliar lymphnodes and nine (15%) distantly. The cosmetic results were considered excellent and good in 60% of the cases and this was most frequently observed in those patients treated by tumorectomy. The conservative treatment of breast cancer seems to be an acceptable option to this pathology. It offers to the patient an extremely satisfactory cosmetic result while keeping surviva! and local control similar to most mutilating treatments.
publishDate 2023
dc.date.none.fl_str_mv 2023-08-07
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dc.language.iso.fl_str_mv por
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dc.source.none.fl_str_mv Revista Brasileira de Cancerologia; Vol. 31 No. 4 (1985): Dec.; 243-248
Revista Brasileira de Cancerologia; Vol. 31 Núm. 4 (1985): dic.; 243-248
Revista Brasileira de Cancerologia; v. 31 n. 4 (1985): dez.; 243-248
2176-9745
reponame:Revista Brasileira de Cancerologia (Online)
instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
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instname_str Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
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reponame_str Revista Brasileira de Cancerologia (Online)
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