Hypofractionated radiotherapy in the management of prostatic cancer

Detalhes bibliográficos
Autor(a) principal: Cury, Fábio Luís Biagini
Data de Publicação: 2004
Outros Autores: Souhami, Luis
Tipo de documento: Artigo
Idioma: por
Título da fonte: Revista Brasileira de Cancerologia (Online)
Texto Completo: https://rbc.inca.gov.br/index.php/revista/article/view/2032
Resumo: Radiotherapy remains a standard treatment option for localized prostate cancer. Over the last few years, improvement of treatment results with the use of higher total doses of irradiation has been extensively studied, particularly since the development of modern and more precise planning and treatment systems. Recently, the interest for the use of hypofractionated irradiation schedules in prostate cancer has increased. Such renovated interest arrives from newer radiobiological data which suggest that the á/â ratio for prostate cancer is much lower than previously estimated. Thus, hypofractionation regimens appear to be an attractive therapeutic option for the treatment of these tumors given that an improved therapeutic index may be achieved by changing the daily radiotherapy dose. This paper critically review the use of hypofractionation in the management of prostatic cancers.
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spelling Hypofractionated radiotherapy in the management of prostatic cancerHipofracionamento no câncer de próstataNeoplasias prostáticasHipofracionamentoÍndice α/βRadioterapiaProstatic neoplasmsHypofractionationα/β RatioRadiotherapyRadiotherapy remains a standard treatment option for localized prostate cancer. Over the last few years, improvement of treatment results with the use of higher total doses of irradiation has been extensively studied, particularly since the development of modern and more precise planning and treatment systems. Recently, the interest for the use of hypofractionated irradiation schedules in prostate cancer has increased. Such renovated interest arrives from newer radiobiological data which suggest that the á/â ratio for prostate cancer is much lower than previously estimated. Thus, hypofractionation regimens appear to be an attractive therapeutic option for the treatment of these tumors given that an improved therapeutic index may be achieved by changing the daily radiotherapy dose. This paper critically review the use of hypofractionation in the management of prostatic cancers.A radioterapia é uma opção terapêutica padrão para o tratamento radical do câncer de próstata localizado. Uma melhora nos índices terapêuticos, através da elevação da dose total do tratamento pelas irradiações, tem sido exaustivamente pesquisada nos últimos anos, com o auxílio de modernos e mais precisos sistemas de planejamento e de tratamento. Recentemente, um interesse renovado sobre o uso do hipofracionamento para o tratamento do câncer de próstata pela radioterapia está sendo observado. Tal mudança de estratégia está relacionada ao novo conceito radiobiológico de que os tumores prostáticos possuem um índice á/â muito mais baixo do que previamente estimado. O hipofracionamento, portanto, parece ser uma opção terapêutica interessante para este tumor, tendo em vista a possibilidade de melhora do índice terapêutico com uma alteração na dose diária de radioterapia. Este trabalho avalia criticamente o valor do hipofracionamento nos tumores prostáticos malignos.INCA2004-09-30info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionRevisão de literaturaapplication/pdfhttps://rbc.inca.gov.br/index.php/revista/article/view/203210.32635/2176-9745.RBC.2004v50n3.2032Revista Brasileira de Cancerologia; Vol. 50 No. 3 (2004): July/Aug./Sept; 239-249Revista Brasileira de Cancerologia; Vol. 50 Núm. 3 (2004): jul./ago/sept.; 239-249Revista Brasileira de Cancerologia; v. 50 n. 3 (2004): jul./ago.set.; 239-2492176-9745reponame:Revista Brasileira de Cancerologia (Online)instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)instacron:INCAporhttps://rbc.inca.gov.br/index.php/revista/article/view/2032/1253Cury, Fábio Luís BiaginiSouhami, Luisinfo:eu-repo/semantics/openAccess2021-11-29T20:32:19Zoai:rbc.inca.gov.br:article/2032Revistahttps://rbc.inca.gov.br/index.php/revistaPUBhttps://rbc.inca.gov.br/index.php/revista/oairbc@inca.gov.br0034-71162176-9745opendoar:2021-11-29T20:32:19Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)false
dc.title.none.fl_str_mv Hypofractionated radiotherapy in the management of prostatic cancer
Hipofracionamento no câncer de próstata
title Hypofractionated radiotherapy in the management of prostatic cancer
spellingShingle Hypofractionated radiotherapy in the management of prostatic cancer
Cury, Fábio Luís Biagini
Neoplasias prostáticas
Hipofracionamento
Índice α/β
Radioterapia
Prostatic neoplasms
Hypofractionation
α/β Ratio
Radiotherapy
title_short Hypofractionated radiotherapy in the management of prostatic cancer
title_full Hypofractionated radiotherapy in the management of prostatic cancer
title_fullStr Hypofractionated radiotherapy in the management of prostatic cancer
title_full_unstemmed Hypofractionated radiotherapy in the management of prostatic cancer
title_sort Hypofractionated radiotherapy in the management of prostatic cancer
author Cury, Fábio Luís Biagini
author_facet Cury, Fábio Luís Biagini
Souhami, Luis
author_role author
author2 Souhami, Luis
author2_role author
dc.contributor.author.fl_str_mv Cury, Fábio Luís Biagini
Souhami, Luis
dc.subject.por.fl_str_mv Neoplasias prostáticas
Hipofracionamento
Índice α/β
Radioterapia
Prostatic neoplasms
Hypofractionation
α/β Ratio
Radiotherapy
topic Neoplasias prostáticas
Hipofracionamento
Índice α/β
Radioterapia
Prostatic neoplasms
Hypofractionation
α/β Ratio
Radiotherapy
description Radiotherapy remains a standard treatment option for localized prostate cancer. Over the last few years, improvement of treatment results with the use of higher total doses of irradiation has been extensively studied, particularly since the development of modern and more precise planning and treatment systems. Recently, the interest for the use of hypofractionated irradiation schedules in prostate cancer has increased. Such renovated interest arrives from newer radiobiological data which suggest that the á/â ratio for prostate cancer is much lower than previously estimated. Thus, hypofractionation regimens appear to be an attractive therapeutic option for the treatment of these tumors given that an improved therapeutic index may be achieved by changing the daily radiotherapy dose. This paper critically review the use of hypofractionation in the management of prostatic cancers.
publishDate 2004
dc.date.none.fl_str_mv 2004-09-30
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Revisão de literatura
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rbc.inca.gov.br/index.php/revista/article/view/2032
10.32635/2176-9745.RBC.2004v50n3.2032
url https://rbc.inca.gov.br/index.php/revista/article/view/2032
identifier_str_mv 10.32635/2176-9745.RBC.2004v50n3.2032
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://rbc.inca.gov.br/index.php/revista/article/view/2032/1253
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv INCA
publisher.none.fl_str_mv INCA
dc.source.none.fl_str_mv Revista Brasileira de Cancerologia; Vol. 50 No. 3 (2004): July/Aug./Sept; 239-249
Revista Brasileira de Cancerologia; Vol. 50 Núm. 3 (2004): jul./ago/sept.; 239-249
Revista Brasileira de Cancerologia; v. 50 n. 3 (2004): jul./ago.set.; 239-249
2176-9745
reponame:Revista Brasileira de Cancerologia (Online)
instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
instacron:INCA
instname_str Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
instacron_str INCA
institution INCA
reponame_str Revista Brasileira de Cancerologia (Online)
collection Revista Brasileira de Cancerologia (Online)
repository.name.fl_str_mv Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
repository.mail.fl_str_mv rbc@inca.gov.br
_version_ 1797042248941043712

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