Cecal Appendix Neuroendocrine Tumors: the Experience of the Brazilian National Cancer Institute

Bibliographic Details
Main Author: Silva, Rodrigo Lopes da
Publication Date: 2010
Other Authors: Linhares, Eduardo, Gonçalves, Rinaldo, Ramos, Cintia
Format: Article
Language: por
Source: Revista Brasileira de Cancerologia (Online)
Download full: https://rbc.inca.gov.br/index.php/revista/article/view/696
Summary: Introduction: The cecal appendix is the second most common site for neuroendocrine tumors in all of the digestive tract, with a relative rate of 25-30%. They are usually diagnosed incidentally during appendectomies or other abdominal surgeries. Objectives: To analyze a series of cases of appendix neuroendocrine tumors treated at the Abdominal-pelvic Surgery Service of the Brazilian National Cancer Institute and describe the approach used in this Service for the treatment of this group of neoplasms. Material and Methods: Report of a series of 13 cases, through the retrospective analysis of the medical records of patients with appendix neuroendocrine tumors treated at the Abdominal-pelvic Surgery Service of the Brazilian National Cancer Institute from 1996 to 2008. Results: The average age at diagnosis was 44.7, with a predominance of women over men in a ratio of 5.5:1. Tumor size ranged from 0.3 to 6 cm, with a median of 2.3 cm. After an average follow up of 32 months, 10 (77%) patients were alive, one (7.7%) missed the follow-up and two (15.3%) died. Conclusion: Appendix neuroendocrine tumors are relatively rare and have good prognosis. The simple appendectomy is the routine surgical treatment and provides cure in most cases. The criteria proposed by the European Neuroendocrine Tumor Society for the treatment of these tumors are easily reproducible and are currently being used as routine in this Service.  
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spelling Cecal Appendix Neuroendocrine Tumors: the Experience of the Brazilian National Cancer InstituteLos Tumores Neuroendocrinos del Apéndice Cecal: Experiencia del Instituto Nacional del CáncerTumores Neuroendócrinos do Apêndice Cecal: Experiência do Instituto Nacional de CâncerApêndiceTumores NeuroendócrinosTumor CarcinoideAppendixNeuroendocrine TumorsCarcinoid TumorApêndiceTumores NeuroendocrinosTumor CarcinoideIntroduction: The cecal appendix is the second most common site for neuroendocrine tumors in all of the digestive tract, with a relative rate of 25-30%. They are usually diagnosed incidentally during appendectomies or other abdominal surgeries. Objectives: To analyze a series of cases of appendix neuroendocrine tumors treated at the Abdominal-pelvic Surgery Service of the Brazilian National Cancer Institute and describe the approach used in this Service for the treatment of this group of neoplasms. Material and Methods: Report of a series of 13 cases, through the retrospective analysis of the medical records of patients with appendix neuroendocrine tumors treated at the Abdominal-pelvic Surgery Service of the Brazilian National Cancer Institute from 1996 to 2008. Results: The average age at diagnosis was 44.7, with a predominance of women over men in a ratio of 5.5:1. Tumor size ranged from 0.3 to 6 cm, with a median of 2.3 cm. After an average follow up of 32 months, 10 (77%) patients were alive, one (7.7%) missed the follow-up and two (15.3%) died. Conclusion: Appendix neuroendocrine tumors are relatively rare and have good prognosis. The simple appendectomy is the routine surgical treatment and provides cure in most cases. The criteria proposed by the European Neuroendocrine Tumor Society for the treatment of these tumors are easily reproducible and are currently being used as routine in this Service.  Introducción: El apéndice cecal es el segundo sitio más frecuente de aparición de los tumores neuroendocrinos en todo el tracto digestivo, con una frecuencia relativa de 25-30%. Por lo general, son diagnosticados de forma incidental durante las apendicectomías u otras cirugías abdominales. Objetivos: Analizar una serie de casos de tumores neuroendocrinos de apéndice tratados en el Servicio de Cirugía Abdominopélvica del Instituto Nacional del Cáncer y describir el enfoque adoptado en este Servicio para el tratamiento de este grupo de neoplasias. Material y métodos: Informe de una serie de 13 casos por análisis retrospectivo de prontuarios de pacientes con tumores neuroendocrinos del apéndice atendidos en el Servicio de Cirugía Abdominopélvica del Instituto Nacional del Cáncer, en el período desde 1996 hasta 2008. Resultados: La edad media de los pacientes al diagnóstico fue de 44,7 años, con un predominio del sexo femenino sobre el masculino en una proporción de 5,5:1. El tamaño tumoral osciló entre 0,3 a 6 cm con una mediana de 2,3 cm. Tras un seguimiento medio de 32 meses, diez (77%) pacientes estaban vivos, uno (7,7%) perdió el seguimiento y dos (15,3%) fallecieron. Conclusión: Los tumores neuroendocrinos apendiculares son relativamente raros y de bueno pronóstico. La apendicectomía simple es el tratamiento quirúrgico de rutina y proporciona la cura en la mayoría de los casos. Los criterios propuestos por European Neuroendocrine Tumor Society para el tratamiento de estos tumores son fáciles de reproducir y, actualmente, se adoptan como rutina en ese Servicio.  Introdução: O apêndice cecal é o segundo sítio mais frequente de surgimento dos tumores neuroendócrinos em todo o trato digestivo, com uma frequência relativa de 25-30%. Geralmente, são diagnosticados incidentalmente durante apendicectomias ou outras cirurgias abdominais. Objetivos: Analisar uma série de casos de tumores neuroendócrinos de apêndice tratados no Serviço de Cirurgia Abdominopélvica do Instituto Nacional de Câncer e descrever a conduta adotada nesse Serviço para o tratamento desse grupo de neoplasias. Material e métodos: Relato de uma série de 13 casos, através da análise retrospectiva de prontuários de pacientes, portadores de tumores neuroendócrinos de apêndice, tratados no Serviço de Cirurgia Abdominopélvica do Instituto Nacional de Câncer, no período de 1996 a 2008. Resultados: A média de idade dos pacientes ao diagnóstico foi de 44,7 anos, com uma predominância do sexo feminino sobre o masculino em uma proporção de 5,5:1. O tamanho do tumor variou de 0,3 a 6 cm com mediana de 2,3 cm. Após um seguimento médio de 32 meses, dez (77%) pacientes estavam vivos, um (7,7%) perdeu o seguimento e dois (15,3%) evoluíram a óbito. Conclusão: Os tumores neuroendócrinos apendiculares são relativamente raros e de bom prognóstico. A apendicectomia simples é o tratamento cirúrgico de rotina e proporciona a cura na maioria dos casos. Os critérios propostos pela European Neuroendocrine Tumor Society para o tratamento desses tumores são de fácil reprodução e, atualmente, são adotados como rotina nesse Serviço.  INCA2010-12-31info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArtigos, Avaliado pelos paresapplication/pdfhttps://rbc.inca.gov.br/index.php/revista/article/view/69610.32635/2176-9745.RBC.2010v56n4.696Revista Brasileira de Cancerologia; Vol. 56 No. 4 (2010): Oct./Nov./Dec.; 463-470Revista Brasileira de Cancerologia; Vol. 56 Núm. 4 (2010): oct./nov./dic.; 463-470Revista Brasileira de Cancerologia; v. 56 n. 4 (2010): out./nov./dez.; 463-4702176-9745reponame:Revista Brasileira de Cancerologia (Online)instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)instacron:INCAporhttps://rbc.inca.gov.br/index.php/revista/article/view/696/466Silva, Rodrigo Lopes da Linhares, Eduardo Gonçalves, Rinaldo Ramos, Cintia info:eu-repo/semantics/openAccess2021-11-29T20:18:03Zoai:rbc.inca.gov.br:article/696Revistahttps://rbc.inca.gov.br/index.php/revistaPUBhttps://rbc.inca.gov.br/index.php/revista/oairbc@inca.gov.br0034-71162176-9745opendoar:2021-11-29T20:18:03Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)false
dc.title.none.fl_str_mv Cecal Appendix Neuroendocrine Tumors: the Experience of the Brazilian National Cancer Institute
Los Tumores Neuroendocrinos del Apéndice Cecal: Experiencia del Instituto Nacional del Cáncer
Tumores Neuroendócrinos do Apêndice Cecal: Experiência do Instituto Nacional de Câncer
title Cecal Appendix Neuroendocrine Tumors: the Experience of the Brazilian National Cancer Institute
spellingShingle Cecal Appendix Neuroendocrine Tumors: the Experience of the Brazilian National Cancer Institute
Silva, Rodrigo Lopes da
Apêndice
Tumores Neuroendócrinos
Tumor Carcinoide
Appendix
Neuroendocrine Tumors
Carcinoid Tumor
Apêndice
Tumores Neuroendocrinos
Tumor Carcinoide
title_short Cecal Appendix Neuroendocrine Tumors: the Experience of the Brazilian National Cancer Institute
title_full Cecal Appendix Neuroendocrine Tumors: the Experience of the Brazilian National Cancer Institute
title_fullStr Cecal Appendix Neuroendocrine Tumors: the Experience of the Brazilian National Cancer Institute
title_full_unstemmed Cecal Appendix Neuroendocrine Tumors: the Experience of the Brazilian National Cancer Institute
title_sort Cecal Appendix Neuroendocrine Tumors: the Experience of the Brazilian National Cancer Institute
author Silva, Rodrigo Lopes da
author_facet Silva, Rodrigo Lopes da
Linhares, Eduardo
Gonçalves, Rinaldo
Ramos, Cintia
author_role author
author2 Linhares, Eduardo
Gonçalves, Rinaldo
Ramos, Cintia
author2_role author
author
author
dc.contributor.author.fl_str_mv Silva, Rodrigo Lopes da
Linhares, Eduardo
Gonçalves, Rinaldo
Ramos, Cintia
dc.subject.por.fl_str_mv Apêndice
Tumores Neuroendócrinos
Tumor Carcinoide
Appendix
Neuroendocrine Tumors
Carcinoid Tumor
Apêndice
Tumores Neuroendocrinos
Tumor Carcinoide
topic Apêndice
Tumores Neuroendócrinos
Tumor Carcinoide
Appendix
Neuroendocrine Tumors
Carcinoid Tumor
Apêndice
Tumores Neuroendocrinos
Tumor Carcinoide
description Introduction: The cecal appendix is the second most common site for neuroendocrine tumors in all of the digestive tract, with a relative rate of 25-30%. They are usually diagnosed incidentally during appendectomies or other abdominal surgeries. Objectives: To analyze a series of cases of appendix neuroendocrine tumors treated at the Abdominal-pelvic Surgery Service of the Brazilian National Cancer Institute and describe the approach used in this Service for the treatment of this group of neoplasms. Material and Methods: Report of a series of 13 cases, through the retrospective analysis of the medical records of patients with appendix neuroendocrine tumors treated at the Abdominal-pelvic Surgery Service of the Brazilian National Cancer Institute from 1996 to 2008. Results: The average age at diagnosis was 44.7, with a predominance of women over men in a ratio of 5.5:1. Tumor size ranged from 0.3 to 6 cm, with a median of 2.3 cm. After an average follow up of 32 months, 10 (77%) patients were alive, one (7.7%) missed the follow-up and two (15.3%) died. Conclusion: Appendix neuroendocrine tumors are relatively rare and have good prognosis. The simple appendectomy is the routine surgical treatment and provides cure in most cases. The criteria proposed by the European Neuroendocrine Tumor Society for the treatment of these tumors are easily reproducible and are currently being used as routine in this Service.  
publishDate 2010
dc.date.none.fl_str_mv 2010-12-31
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Artigos, Avaliado pelos pares
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rbc.inca.gov.br/index.php/revista/article/view/696
10.32635/2176-9745.RBC.2010v56n4.696
url https://rbc.inca.gov.br/index.php/revista/article/view/696
identifier_str_mv 10.32635/2176-9745.RBC.2010v56n4.696
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://rbc.inca.gov.br/index.php/revista/article/view/696/466
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv INCA
publisher.none.fl_str_mv INCA
dc.source.none.fl_str_mv Revista Brasileira de Cancerologia; Vol. 56 No. 4 (2010): Oct./Nov./Dec.; 463-470
Revista Brasileira de Cancerologia; Vol. 56 Núm. 4 (2010): oct./nov./dic.; 463-470
Revista Brasileira de Cancerologia; v. 56 n. 4 (2010): out./nov./dez.; 463-470
2176-9745
reponame:Revista Brasileira de Cancerologia (Online)
instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
instacron:INCA
instname_str Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
instacron_str INCA
institution INCA
reponame_str Revista Brasileira de Cancerologia (Online)
collection Revista Brasileira de Cancerologia (Online)
repository.name.fl_str_mv Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
repository.mail.fl_str_mv rbc@inca.gov.br
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