Cecal Appendix Neuroendocrine Tumors: the Experience of the Brazilian National Cancer Institute
Autor(a) principal: | |
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Data de Publicação: | 2010 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Revista Brasileira de Cancerologia (Online) |
Texto Completo: | https://rbc.inca.gov.br/index.php/revista/article/view/696 |
Resumo: | Introduction: The cecal appendix is the second most common site for neuroendocrine tumors in all of the digestive tract, with a relative rate of 25-30%. They are usually diagnosed incidentally during appendectomies or other abdominal surgeries. Objectives: To analyze a series of cases of appendix neuroendocrine tumors treated at the Abdominal-pelvic Surgery Service of the Brazilian National Cancer Institute and describe the approach used in this Service for the treatment of this group of neoplasms. Material and Methods: Report of a series of 13 cases, through the retrospective analysis of the medical records of patients with appendix neuroendocrine tumors treated at the Abdominal-pelvic Surgery Service of the Brazilian National Cancer Institute from 1996 to 2008. Results: The average age at diagnosis was 44.7, with a predominance of women over men in a ratio of 5.5:1. Tumor size ranged from 0.3 to 6 cm, with a median of 2.3 cm. After an average follow up of 32 months, 10 (77%) patients were alive, one (7.7%) missed the follow-up and two (15.3%) died. Conclusion: Appendix neuroendocrine tumors are relatively rare and have good prognosis. The simple appendectomy is the routine surgical treatment and provides cure in most cases. The criteria proposed by the European Neuroendocrine Tumor Society for the treatment of these tumors are easily reproducible and are currently being used as routine in this Service. |
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Cecal Appendix Neuroendocrine Tumors: the Experience of the Brazilian National Cancer InstituteLos Tumores Neuroendocrinos del Apéndice Cecal: Experiencia del Instituto Nacional del CáncerTumores Neuroendócrinos do Apêndice Cecal: Experiência do Instituto Nacional de CâncerApêndiceTumores NeuroendócrinosTumor CarcinoideAppendixNeuroendocrine TumorsCarcinoid TumorApêndiceTumores NeuroendocrinosTumor CarcinoideIntroduction: The cecal appendix is the second most common site for neuroendocrine tumors in all of the digestive tract, with a relative rate of 25-30%. They are usually diagnosed incidentally during appendectomies or other abdominal surgeries. Objectives: To analyze a series of cases of appendix neuroendocrine tumors treated at the Abdominal-pelvic Surgery Service of the Brazilian National Cancer Institute and describe the approach used in this Service for the treatment of this group of neoplasms. Material and Methods: Report of a series of 13 cases, through the retrospective analysis of the medical records of patients with appendix neuroendocrine tumors treated at the Abdominal-pelvic Surgery Service of the Brazilian National Cancer Institute from 1996 to 2008. Results: The average age at diagnosis was 44.7, with a predominance of women over men in a ratio of 5.5:1. Tumor size ranged from 0.3 to 6 cm, with a median of 2.3 cm. After an average follow up of 32 months, 10 (77%) patients were alive, one (7.7%) missed the follow-up and two (15.3%) died. Conclusion: Appendix neuroendocrine tumors are relatively rare and have good prognosis. The simple appendectomy is the routine surgical treatment and provides cure in most cases. The criteria proposed by the European Neuroendocrine Tumor Society for the treatment of these tumors are easily reproducible and are currently being used as routine in this Service. Introducción: El apéndice cecal es el segundo sitio más frecuente de aparición de los tumores neuroendocrinos en todo el tracto digestivo, con una frecuencia relativa de 25-30%. Por lo general, son diagnosticados de forma incidental durante las apendicectomías u otras cirugías abdominales. Objetivos: Analizar una serie de casos de tumores neuroendocrinos de apéndice tratados en el Servicio de Cirugía Abdominopélvica del Instituto Nacional del Cáncer y describir el enfoque adoptado en este Servicio para el tratamiento de este grupo de neoplasias. Material y métodos: Informe de una serie de 13 casos por análisis retrospectivo de prontuarios de pacientes con tumores neuroendocrinos del apéndice atendidos en el Servicio de Cirugía Abdominopélvica del Instituto Nacional del Cáncer, en el período desde 1996 hasta 2008. Resultados: La edad media de los pacientes al diagnóstico fue de 44,7 años, con un predominio del sexo femenino sobre el masculino en una proporción de 5,5:1. El tamaño tumoral osciló entre 0,3 a 6 cm con una mediana de 2,3 cm. Tras un seguimiento medio de 32 meses, diez (77%) pacientes estaban vivos, uno (7,7%) perdió el seguimiento y dos (15,3%) fallecieron. Conclusión: Los tumores neuroendocrinos apendiculares son relativamente raros y de bueno pronóstico. La apendicectomía simple es el tratamiento quirúrgico de rutina y proporciona la cura en la mayoría de los casos. Los criterios propuestos por European Neuroendocrine Tumor Society para el tratamiento de estos tumores son fáciles de reproducir y, actualmente, se adoptan como rutina en ese Servicio. Introdução: O apêndice cecal é o segundo sítio mais frequente de surgimento dos tumores neuroendócrinos em todo o trato digestivo, com uma frequência relativa de 25-30%. Geralmente, são diagnosticados incidentalmente durante apendicectomias ou outras cirurgias abdominais. Objetivos: Analisar uma série de casos de tumores neuroendócrinos de apêndice tratados no Serviço de Cirurgia Abdominopélvica do Instituto Nacional de Câncer e descrever a conduta adotada nesse Serviço para o tratamento desse grupo de neoplasias. Material e métodos: Relato de uma série de 13 casos, através da análise retrospectiva de prontuários de pacientes, portadores de tumores neuroendócrinos de apêndice, tratados no Serviço de Cirurgia Abdominopélvica do Instituto Nacional de Câncer, no período de 1996 a 2008. Resultados: A média de idade dos pacientes ao diagnóstico foi de 44,7 anos, com uma predominância do sexo feminino sobre o masculino em uma proporção de 5,5:1. O tamanho do tumor variou de 0,3 a 6 cm com mediana de 2,3 cm. Após um seguimento médio de 32 meses, dez (77%) pacientes estavam vivos, um (7,7%) perdeu o seguimento e dois (15,3%) evoluíram a óbito. Conclusão: Os tumores neuroendócrinos apendiculares são relativamente raros e de bom prognóstico. A apendicectomia simples é o tratamento cirúrgico de rotina e proporciona a cura na maioria dos casos. Os critérios propostos pela European Neuroendocrine Tumor Society para o tratamento desses tumores são de fácil reprodução e, atualmente, são adotados como rotina nesse Serviço. INCA2010-12-31info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArtigos, Avaliado pelos paresapplication/pdfhttps://rbc.inca.gov.br/index.php/revista/article/view/69610.32635/2176-9745.RBC.2010v56n4.696Revista Brasileira de Cancerologia; Vol. 56 No. 4 (2010): Oct./Nov./Dec.; 463-470Revista Brasileira de Cancerologia; Vol. 56 Núm. 4 (2010): oct./nov./dic.; 463-470Revista Brasileira de Cancerologia; v. 56 n. 4 (2010): out./nov./dez.; 463-4702176-9745reponame:Revista Brasileira de Cancerologia (Online)instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)instacron:INCAporhttps://rbc.inca.gov.br/index.php/revista/article/view/696/466Silva, Rodrigo Lopes da Linhares, Eduardo Gonçalves, Rinaldo Ramos, Cintia info:eu-repo/semantics/openAccess2021-11-29T20:18:03Zoai:rbc.inca.gov.br:article/696Revistahttps://rbc.inca.gov.br/index.php/revistaPUBhttps://rbc.inca.gov.br/index.php/revista/oairbc@inca.gov.br0034-71162176-9745opendoar:2021-11-29T20:18:03Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)false |
dc.title.none.fl_str_mv |
Cecal Appendix Neuroendocrine Tumors: the Experience of the Brazilian National Cancer Institute Los Tumores Neuroendocrinos del Apéndice Cecal: Experiencia del Instituto Nacional del Cáncer Tumores Neuroendócrinos do Apêndice Cecal: Experiência do Instituto Nacional de Câncer |
title |
Cecal Appendix Neuroendocrine Tumors: the Experience of the Brazilian National Cancer Institute |
spellingShingle |
Cecal Appendix Neuroendocrine Tumors: the Experience of the Brazilian National Cancer Institute Silva, Rodrigo Lopes da Apêndice Tumores Neuroendócrinos Tumor Carcinoide Appendix Neuroendocrine Tumors Carcinoid Tumor Apêndice Tumores Neuroendocrinos Tumor Carcinoide |
title_short |
Cecal Appendix Neuroendocrine Tumors: the Experience of the Brazilian National Cancer Institute |
title_full |
Cecal Appendix Neuroendocrine Tumors: the Experience of the Brazilian National Cancer Institute |
title_fullStr |
Cecal Appendix Neuroendocrine Tumors: the Experience of the Brazilian National Cancer Institute |
title_full_unstemmed |
Cecal Appendix Neuroendocrine Tumors: the Experience of the Brazilian National Cancer Institute |
title_sort |
Cecal Appendix Neuroendocrine Tumors: the Experience of the Brazilian National Cancer Institute |
author |
Silva, Rodrigo Lopes da |
author_facet |
Silva, Rodrigo Lopes da Linhares, Eduardo Gonçalves, Rinaldo Ramos, Cintia |
author_role |
author |
author2 |
Linhares, Eduardo Gonçalves, Rinaldo Ramos, Cintia |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Silva, Rodrigo Lopes da Linhares, Eduardo Gonçalves, Rinaldo Ramos, Cintia |
dc.subject.por.fl_str_mv |
Apêndice Tumores Neuroendócrinos Tumor Carcinoide Appendix Neuroendocrine Tumors Carcinoid Tumor Apêndice Tumores Neuroendocrinos Tumor Carcinoide |
topic |
Apêndice Tumores Neuroendócrinos Tumor Carcinoide Appendix Neuroendocrine Tumors Carcinoid Tumor Apêndice Tumores Neuroendocrinos Tumor Carcinoide |
description |
Introduction: The cecal appendix is the second most common site for neuroendocrine tumors in all of the digestive tract, with a relative rate of 25-30%. They are usually diagnosed incidentally during appendectomies or other abdominal surgeries. Objectives: To analyze a series of cases of appendix neuroendocrine tumors treated at the Abdominal-pelvic Surgery Service of the Brazilian National Cancer Institute and describe the approach used in this Service for the treatment of this group of neoplasms. Material and Methods: Report of a series of 13 cases, through the retrospective analysis of the medical records of patients with appendix neuroendocrine tumors treated at the Abdominal-pelvic Surgery Service of the Brazilian National Cancer Institute from 1996 to 2008. Results: The average age at diagnosis was 44.7, with a predominance of women over men in a ratio of 5.5:1. Tumor size ranged from 0.3 to 6 cm, with a median of 2.3 cm. After an average follow up of 32 months, 10 (77%) patients were alive, one (7.7%) missed the follow-up and two (15.3%) died. Conclusion: Appendix neuroendocrine tumors are relatively rare and have good prognosis. The simple appendectomy is the routine surgical treatment and provides cure in most cases. The criteria proposed by the European Neuroendocrine Tumor Society for the treatment of these tumors are easily reproducible and are currently being used as routine in this Service. |
publishDate |
2010 |
dc.date.none.fl_str_mv |
2010-12-31 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Artigos, Avaliado pelos pares |
format |
article |
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publishedVersion |
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https://rbc.inca.gov.br/index.php/revista/article/view/696 10.32635/2176-9745.RBC.2010v56n4.696 |
url |
https://rbc.inca.gov.br/index.php/revista/article/view/696 |
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10.32635/2176-9745.RBC.2010v56n4.696 |
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https://rbc.inca.gov.br/index.php/revista/article/view/696/466 |
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info:eu-repo/semantics/openAccess |
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openAccess |
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INCA |
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Revista Brasileira de Cancerologia; Vol. 56 No. 4 (2010): Oct./Nov./Dec.; 463-470 Revista Brasileira de Cancerologia; Vol. 56 Núm. 4 (2010): oct./nov./dic.; 463-470 Revista Brasileira de Cancerologia; v. 56 n. 4 (2010): out./nov./dez.; 463-470 2176-9745 reponame:Revista Brasileira de Cancerologia (Online) instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA) instacron:INCA |
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Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA) |
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INCA |
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Revista Brasileira de Cancerologia (Online) |
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Revista Brasileira de Cancerologia (Online) |
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Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA) |
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rbc@inca.gov.br |
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