Pregnancy in patients with non-cirrhotic portal hypertension: a systematic review of the literature
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Amadeus International Multidisciplinary Journal |
Texto Completo: | https://amadeusjournal.emnuvens.com.br/amadeus/article/view/181 |
Resumo: | Non-cirrhotic portal hypertension (NCPH) includes a heterogeneous group of conditions. The aim of this study was to understand pregnancy in patients with non-cirrhotic portal hypertension. This is a scope review study, which is used to map evidence on a given phenomenon and identify existing gaps. Data collection was carried out between June and August 2022. The investigations were carried out in the US National Library of Medicine, National Institutes of Health (PubMed), Latin American and Caribbean Literature in Health Sciences (Lilacs), SciVerse, and Scopus (Scopus), Web of Science. The acronym 'PCC' was used, with P for population (pregnancy), C for concept (Patients) and C for context (non-cirrhotic portal hypertension). We identified 19 studies that reported at least one outcome of interest for the review. Bleeding from varices is one of the most common clinical manifestations in HPNC. Prenatal care with correction of high-risk varicose veins has satisfactory results during pregnancy. Cesarean section should be reserved for obstetric indications only. Pregnancy can be allowed and successfully managed in patients with HPNC. Prophylaxis for variceal bleeding can be done through endoscopic variceal ligation (EVL) or β-blockers. A previous history of variceal bleeding is a risk factor for bleeding during subsequent pregnancies6. Thus, combination therapy with EVL and β-blocker is preferred for patients with varices and a previous history of variceal bleeding. Thus, there is a scarcity of data in the literature on the occurrence of pregnancy and its outcome in patients with non-cirrhotic portal hypertension. Despite a significant incidence of complications related to portal hypertension, overall pregnancy outcomes have remained favorable in women with non-cirrhotic idiopathic portal hypertension. About 15% of patients with [non-cirrhotic idiopathic portal hypertension (INCPH)] are women of childbearing age who may become pregnant. However, pregnancy and the postpartum period are prothrombotic states and pregnancy can exacerbate portal hypertension. |
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Pregnancy in patients with non-cirrhotic portal hypertension: a systematic review of the literatureGravidez em Pacientes com Hipertensão Portal não Cirrotica: Uma Revisão Sistemática da LiteraturaNon-cirrhotic portal hypertension (NCPH) includes a heterogeneous group of conditions. The aim of this study was to understand pregnancy in patients with non-cirrhotic portal hypertension. This is a scope review study, which is used to map evidence on a given phenomenon and identify existing gaps. Data collection was carried out between June and August 2022. The investigations were carried out in the US National Library of Medicine, National Institutes of Health (PubMed), Latin American and Caribbean Literature in Health Sciences (Lilacs), SciVerse, and Scopus (Scopus), Web of Science. The acronym 'PCC' was used, with P for population (pregnancy), C for concept (Patients) and C for context (non-cirrhotic portal hypertension). We identified 19 studies that reported at least one outcome of interest for the review. Bleeding from varices is one of the most common clinical manifestations in HPNC. Prenatal care with correction of high-risk varicose veins has satisfactory results during pregnancy. Cesarean section should be reserved for obstetric indications only. Pregnancy can be allowed and successfully managed in patients with HPNC. Prophylaxis for variceal bleeding can be done through endoscopic variceal ligation (EVL) or β-blockers. A previous history of variceal bleeding is a risk factor for bleeding during subsequent pregnancies6. Thus, combination therapy with EVL and β-blocker is preferred for patients with varices and a previous history of variceal bleeding. Thus, there is a scarcity of data in the literature on the occurrence of pregnancy and its outcome in patients with non-cirrhotic portal hypertension. Despite a significant incidence of complications related to portal hypertension, overall pregnancy outcomes have remained favorable in women with non-cirrhotic idiopathic portal hypertension. About 15% of patients with [non-cirrhotic idiopathic portal hypertension (INCPH)] are women of childbearing age who may become pregnant. However, pregnancy and the postpartum period are prothrombotic states and pregnancy can exacerbate portal hypertension.A hipertensão portal não cirrótica (HPNC) inclui um grupo heterogêneo de condições. O objetivo deste estudo foi comprender a gravidez em pacientes com hipertensão portal não cirrotica. Trata-se de um estudo de revisão de escopo, o qual é utilizado para mapear evidências sobre um determinado fenômeno e identificar as lacunas existentes. A coleta dos dados foi realizada entre junho a agosto de 2022. As investigações foram realizadas nas bases de dados US National Library of Medicine National Institutes of Health (PubMed), Literatura Latino-Americana e do Caribe em Ciências da Saúde (Lilacs), SciVerse Scopus (Scopus), Web of Science. Utilizou-se o acrômio ‘PCC’, sendo P para população (gravidez), C para conceito (Pacientes) e C para contexto (hipertensão portal não cirrotica). Identificamos 19 estudos que relataram pelo menos um resultado de interesse para a revisão. O sangramento de varizes é uma das mais manifestações clínicas comum na HPNC. Pré-natal com correção de varizes de alto risco tem resultado satisfatório durantea gravidez. Cesariana deve ser reservada apenas para indicações obstétricas. A gravidez pode ser permitida e gerenciada com sucesso em pacientes com HPNC. A profilaxia para sangramento por varizes pode ser feita por meio de ligadura endoscópica de varizes (EVL) ou β-bloqueadores. História prévia de sangramento por varizes é um fator de risco para sangramento durante gestações subsequentes6. Assim, a terapia combinada com EVL e β-bloqueador é preferida para pacientes com varizes e história prévia de sangramento de varizes. Assim, há escassez de dados na literatura sobre a ocorrência de gravidez e seu desfecho em pacientes com hipertensão portal não cirrótica. Apesar de uma incidência significativa de complicações relacionadas à hipertensão portal, os resultados gerais da gravidez permaneceram favoráveis em mulheres com hipertensão portal idiopática não cirrótica. Cerca de 15% dos pacientes com [hipertensão portal idiopática não cirrótica (INCPH)] são mulheres em idade fértil, que podem engravidar. No entanto, a gravidez e o pós-parto são estados pró-trombóticos e a gravidez pode exacerbar a hipertensão portal.Instituto Persona de Educação Superior2022-12-30info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://amadeusjournal.emnuvens.com.br/amadeus/article/view/18110.14295/aimj.v6i12.181Amadeus International Multidisciplinary Journal; Vol. 6 No. 12 (2022); 43-61Amadeus International Multidisciplinary Journal; v. 6 n. 12 (2022); 43-612525-8281reponame:Amadeus International Multidisciplinary Journalinstname:Instituto Persona de Educação Superiorinstacron:IPESenghttps://amadeusjournal.emnuvens.com.br/amadeus/article/view/181/351Copyright (c) 2022 Rafael Rocha Andrade de Figueirêdo, Francisco Ananias Mamede de Morais Junior, Amanda Maria Costa Silva, Luciana Sobreira de Matos, Maria Aparecida Daves de Moraes Bregense, Páblina Daves de Moraes Bregense, André Luis Gomes Ramalhohttps://creativecommons.org/licenses/by-nc/4.0info:eu-repo/semantics/openAccessFigueirêdo, Rafael Rocha Andrade de Morais Junior, Francisco Ananias Mamede deSilva, Amanda Maria Costa Matos, Luciana Sobreira deBregense, Maria Aparecida Daves de MoraesDaves de Moraes Bregense, PáblinaRamalho, André Luis Gomes2023-11-20T15:28:02Zoai:ojs.emnuvens.com.br:article/181Revistahttps://amadeusjournal.emnuvens.com.br/amadeus/indexPRIhttps://amadeusjournal.emnuvens.com.br/amadeus/oaiamadeusjournal@gmail.com2525-82812525-8281opendoar:2023-11-20T15:28:02Amadeus International Multidisciplinary Journal - Instituto Persona de Educação Superiorfalse |
dc.title.none.fl_str_mv |
Pregnancy in patients with non-cirrhotic portal hypertension: a systematic review of the literature Gravidez em Pacientes com Hipertensão Portal não Cirrotica: Uma Revisão Sistemática da Literatura |
title |
Pregnancy in patients with non-cirrhotic portal hypertension: a systematic review of the literature |
spellingShingle |
Pregnancy in patients with non-cirrhotic portal hypertension: a systematic review of the literature Figueirêdo, Rafael Rocha Andrade de |
title_short |
Pregnancy in patients with non-cirrhotic portal hypertension: a systematic review of the literature |
title_full |
Pregnancy in patients with non-cirrhotic portal hypertension: a systematic review of the literature |
title_fullStr |
Pregnancy in patients with non-cirrhotic portal hypertension: a systematic review of the literature |
title_full_unstemmed |
Pregnancy in patients with non-cirrhotic portal hypertension: a systematic review of the literature |
title_sort |
Pregnancy in patients with non-cirrhotic portal hypertension: a systematic review of the literature |
author |
Figueirêdo, Rafael Rocha Andrade de |
author_facet |
Figueirêdo, Rafael Rocha Andrade de Morais Junior, Francisco Ananias Mamede de Silva, Amanda Maria Costa Matos, Luciana Sobreira de Bregense, Maria Aparecida Daves de Moraes Daves de Moraes Bregense, Páblina Ramalho, André Luis Gomes |
author_role |
author |
author2 |
Morais Junior, Francisco Ananias Mamede de Silva, Amanda Maria Costa Matos, Luciana Sobreira de Bregense, Maria Aparecida Daves de Moraes Daves de Moraes Bregense, Páblina Ramalho, André Luis Gomes |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Figueirêdo, Rafael Rocha Andrade de Morais Junior, Francisco Ananias Mamede de Silva, Amanda Maria Costa Matos, Luciana Sobreira de Bregense, Maria Aparecida Daves de Moraes Daves de Moraes Bregense, Páblina Ramalho, André Luis Gomes |
description |
Non-cirrhotic portal hypertension (NCPH) includes a heterogeneous group of conditions. The aim of this study was to understand pregnancy in patients with non-cirrhotic portal hypertension. This is a scope review study, which is used to map evidence on a given phenomenon and identify existing gaps. Data collection was carried out between June and August 2022. The investigations were carried out in the US National Library of Medicine, National Institutes of Health (PubMed), Latin American and Caribbean Literature in Health Sciences (Lilacs), SciVerse, and Scopus (Scopus), Web of Science. The acronym 'PCC' was used, with P for population (pregnancy), C for concept (Patients) and C for context (non-cirrhotic portal hypertension). We identified 19 studies that reported at least one outcome of interest for the review. Bleeding from varices is one of the most common clinical manifestations in HPNC. Prenatal care with correction of high-risk varicose veins has satisfactory results during pregnancy. Cesarean section should be reserved for obstetric indications only. Pregnancy can be allowed and successfully managed in patients with HPNC. Prophylaxis for variceal bleeding can be done through endoscopic variceal ligation (EVL) or β-blockers. A previous history of variceal bleeding is a risk factor for bleeding during subsequent pregnancies6. Thus, combination therapy with EVL and β-blocker is preferred for patients with varices and a previous history of variceal bleeding. Thus, there is a scarcity of data in the literature on the occurrence of pregnancy and its outcome in patients with non-cirrhotic portal hypertension. Despite a significant incidence of complications related to portal hypertension, overall pregnancy outcomes have remained favorable in women with non-cirrhotic idiopathic portal hypertension. About 15% of patients with [non-cirrhotic idiopathic portal hypertension (INCPH)] are women of childbearing age who may become pregnant. However, pregnancy and the postpartum period are prothrombotic states and pregnancy can exacerbate portal hypertension. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-12-30 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://amadeusjournal.emnuvens.com.br/amadeus/article/view/181 10.14295/aimj.v6i12.181 |
url |
https://amadeusjournal.emnuvens.com.br/amadeus/article/view/181 |
identifier_str_mv |
10.14295/aimj.v6i12.181 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://amadeusjournal.emnuvens.com.br/amadeus/article/view/181/351 |
dc.rights.driver.fl_str_mv |
https://creativecommons.org/licenses/by-nc/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by-nc/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Instituto Persona de Educação Superior |
publisher.none.fl_str_mv |
Instituto Persona de Educação Superior |
dc.source.none.fl_str_mv |
Amadeus International Multidisciplinary Journal; Vol. 6 No. 12 (2022); 43-61 Amadeus International Multidisciplinary Journal; v. 6 n. 12 (2022); 43-61 2525-8281 reponame:Amadeus International Multidisciplinary Journal instname:Instituto Persona de Educação Superior instacron:IPES |
instname_str |
Instituto Persona de Educação Superior |
instacron_str |
IPES |
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IPES |
reponame_str |
Amadeus International Multidisciplinary Journal |
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Amadeus International Multidisciplinary Journal |
repository.name.fl_str_mv |
Amadeus International Multidisciplinary Journal - Instituto Persona de Educação Superior |
repository.mail.fl_str_mv |
amadeusjournal@gmail.com |
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1797051333736398848 |