Healthy human aging: intrinsic and environmental factors

Bibliographic Details
Main Author: Sgarbieri, Valdemiro Carlos
Publication Date: 2017
Other Authors: Pacheco, Maria Teresa Bertoldo
Format: Article
Language: eng
Source: Repositório do Instituto de Tecnologia de Alimentos
Download full: http://repositorio.ital.sp.gov.br/jspui/handle/123456789/259
Summary: This review is an attempt to compile current knowledge on concepts and transformations that occur naturally in the human body and that characterize what is defined today as biological aging with quality of life and longevity. Many authors define natural aging as a continuous and uninterrupted process, which occurs in the human body causing structural and functional changes, classified as: cumulative, progressive, intrinsic and deleterious (CUPID). Usually these changes begin early in life and culminate in physical death. Genetic, chemical and biochemical changes lead to progressive degeneration of cells, tissues and organs, body systems and the organism as a whole, leading to loss of structures and functions due to aging. All these changes were discussed in some detail in the review here presented. We concluded that aging is not genetically determined, resulting in the accumulation of cellular and tissue damage, particularly in chromatin and DNA within cells, in addition to structural and bioactive proteins that command the general metabolism. Environmental factors such as feeding (nutrition) and lifestyle were also discussed.
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spelling Healthy human aging: intrinsic and environmental factorsBiological agingCUPIDNatural agingProgressive degenerationThis review is an attempt to compile current knowledge on concepts and transformations that occur naturally in the human body and that characterize what is defined today as biological aging with quality of life and longevity. Many authors define natural aging as a continuous and uninterrupted process, which occurs in the human body causing structural and functional changes, classified as: cumulative, progressive, intrinsic and deleterious (CUPID). Usually these changes begin early in life and culminate in physical death. Genetic, chemical and biochemical changes lead to progressive degeneration of cells, tissues and organs, body systems and the organism as a whole, leading to loss of structures and functions due to aging. All these changes were discussed in some detail in the review here presented. We concluded that aging is not genetically determined, resulting in the accumulation of cellular and tissue damage, particularly in chromatin and DNA within cells, in addition to structural and bioactive proteins that command the general metabolism. Environmental factors such as feeding (nutrition) and lifestyle were also discussed.Sgarbieri, Valdemiro CarlosPacheco, Maria Teresa Bertoldo2022-03-28T19:53:53Z2022-03-28T19:53:53Z2017info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfBraz. J. Food Technol., v. 20, e2017007, 2017. doi.org/10.1590/1981-6723.00717http://repositorio.ital.sp.gov.br/jspui/handle/123456789/259reponame:Repositório do Instituto de Tecnologia de Alimentosinstname:Instituto de Tecnologia de Alimentos (ITAL)instacron:ITALenginfo:eu-repo/semantics/openAccess2022-05-20T16:14:05Zoai:http://repositorio.ital.sp.gov.br:123456789/259Repositório InstitucionalPUBhttp://repositorio.ital.sp.gov.br/oai/requestbjftsec@ital.sp.gov.br || bjftsec@ital.sp.gov.bropendoar:2022-05-20T16:14:05Repositório do Instituto de Tecnologia de Alimentos - Instituto de Tecnologia de Alimentos (ITAL)false
dc.title.none.fl_str_mv Healthy human aging: intrinsic and environmental factors
title Healthy human aging: intrinsic and environmental factors
spellingShingle Healthy human aging: intrinsic and environmental factors
Sgarbieri, Valdemiro Carlos
Biological aging
CUPID
Natural aging
Progressive degeneration
title_short Healthy human aging: intrinsic and environmental factors
title_full Healthy human aging: intrinsic and environmental factors
title_fullStr Healthy human aging: intrinsic and environmental factors
title_full_unstemmed Healthy human aging: intrinsic and environmental factors
title_sort Healthy human aging: intrinsic and environmental factors
author Sgarbieri, Valdemiro Carlos
author_facet Sgarbieri, Valdemiro Carlos
Pacheco, Maria Teresa Bertoldo
author_role author
author2 Pacheco, Maria Teresa Bertoldo
author2_role author
dc.contributor.none.fl_str_mv







dc.contributor.author.fl_str_mv Sgarbieri, Valdemiro Carlos
Pacheco, Maria Teresa Bertoldo
dc.subject.none.fl_str_mv

dc.subject.por.fl_str_mv Biological aging
CUPID
Natural aging
Progressive degeneration
topic Biological aging
CUPID
Natural aging
Progressive degeneration
description This review is an attempt to compile current knowledge on concepts and transformations that occur naturally in the human body and that characterize what is defined today as biological aging with quality of life and longevity. Many authors define natural aging as a continuous and uninterrupted process, which occurs in the human body causing structural and functional changes, classified as: cumulative, progressive, intrinsic and deleterious (CUPID). Usually these changes begin early in life and culminate in physical death. Genetic, chemical and biochemical changes lead to progressive degeneration of cells, tissues and organs, body systems and the organism as a whole, leading to loss of structures and functions due to aging. All these changes were discussed in some detail in the review here presented. We concluded that aging is not genetically determined, resulting in the accumulation of cellular and tissue damage, particularly in chromatin and DNA within cells, in addition to structural and bioactive proteins that command the general metabolism. Environmental factors such as feeding (nutrition) and lifestyle were also discussed.
publishDate 2017
dc.date.none.fl_str_mv




2017
2022-03-28T19:53:53Z
2022-03-28T19:53:53Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv

dc.identifier.uri.fl_str_mv Braz. J. Food Technol., v. 20, e2017007, 2017. doi.org/10.1590/1981-6723.00717
http://repositorio.ital.sp.gov.br/jspui/handle/123456789/259
identifier_str_mv
Braz. J. Food Technol., v. 20, e2017007, 2017. doi.org/10.1590/1981-6723.00717
url http://repositorio.ital.sp.gov.br/jspui/handle/123456789/259
dc.language.none.fl_str_mv
dc.language.iso.fl_str_mv eng
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language eng
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dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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eu_rights_str_mv openAccess
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application/pdf
dc.publisher.none.fl_str_mv

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reponame:Repositório do Instituto de Tecnologia de Alimentos
instname:Instituto de Tecnologia de Alimentos (ITAL)
instacron:ITAL
instname_str Instituto de Tecnologia de Alimentos (ITAL)
instacron_str ITAL
institution ITAL
reponame_str Repositório do Instituto de Tecnologia de Alimentos
collection Repositório do Instituto de Tecnologia de Alimentos
repository.name.fl_str_mv Repositório do Instituto de Tecnologia de Alimentos - Instituto de Tecnologia de Alimentos (ITAL)
repository.mail.fl_str_mv bjftsec@ital.sp.gov.br || bjftsec@ital.sp.gov.br
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