Intellectual performance profi le of a sample of children and adolescents from Brazil with 22q11.2 Deletion Syndrome (22q11.2DS) based on the Wechsler Scale
Autor(a) principal: | |
---|---|
Data de Publicação: | 2023 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Estudos de Psicologia (Campinas) |
Texto Completo: | https://periodicos.puc-campinas.edu.br/estpsi/article/view/7406 |
Resumo: | The 22q11.2 Deletion Syndrome (22q11.2DS), the most common human chromosome microdeletion syndrome, is associated with a very heterogeneous neurocognitive phenotype. One of the main characteristics of the syndrome spectrum is the intellectual variability, which encompasses average performance and intellectual disability and discrepancies between Verbal Intelligence Quotient and Performance Verbal Intelligence Quotient, with greater impairment in nonverbal tasks. The present study aimed at investigating the intellectual performance aspects of a 21children and adolescents sample from Brazil who had been diagnosed with 22q11.2DS, based on the Wechsler Intelligence Scale for Children - 4th edition. The samples were reviewed considering the differences between indices. The results revealed an Full Scale Intelligence Quotient predominant in the borderline range (42 to 104) and a significant discrepancy between the indices of Verbal Comprehension and Perceptual Reasoning in 42% of the sample. With regard to the performance in the subtests alone, a better performance was found in Similarities, whereas block design, matrix reasoning, digit span and letter-number sequencing subtests were the most challenging. These findings indicate that a comprehensive assessment of intellectual performance aspects covering the different measures of the Wechsler Intelligence Scale may contribute to a broader understanding of the neurocognitive phenotype associated with 22q11.2DS. |
id |
PUC_CAMP-3_0788a1f747b033822f8ec93089a096f2 |
---|---|
oai_identifier_str |
oai:ojs.periodicos.puc-campinas.edu.br:article/7406 |
network_acronym_str |
PUC_CAMP-3 |
network_name_str |
Estudos de Psicologia (Campinas) |
repository_id_str |
|
spelling |
Intellectual performance profi le of a sample of children and adolescents from Brazil with 22q11.2 Deletion Syndrome (22q11.2DS) based on the Wechsler ScalePerfi l de desempenho intelectual de uma amostra brasileira de crianças e adolescentes com Síndrome da Deleção 22q11.2 (22q11.2DS) com base na Escala WechslerDiGeorge syndromeGenetics, behavioralNeuropsychologyWechsler ScalesSíndrome de DiGeorgeGenética comportamentalNeuropsicologiaEscalas de WechslerThe 22q11.2 Deletion Syndrome (22q11.2DS), the most common human chromosome microdeletion syndrome, is associated with a very heterogeneous neurocognitive phenotype. One of the main characteristics of the syndrome spectrum is the intellectual variability, which encompasses average performance and intellectual disability and discrepancies between Verbal Intelligence Quotient and Performance Verbal Intelligence Quotient, with greater impairment in nonverbal tasks. The present study aimed at investigating the intellectual performance aspects of a 21children and adolescents sample from Brazil who had been diagnosed with 22q11.2DS, based on the Wechsler Intelligence Scale for Children - 4th edition. The samples were reviewed considering the differences between indices. The results revealed an Full Scale Intelligence Quotient predominant in the borderline range (42 to 104) and a significant discrepancy between the indices of Verbal Comprehension and Perceptual Reasoning in 42% of the sample. With regard to the performance in the subtests alone, a better performance was found in Similarities, whereas block design, matrix reasoning, digit span and letter-number sequencing subtests were the most challenging. These findings indicate that a comprehensive assessment of intellectual performance aspects covering the different measures of the Wechsler Intelligence Scale may contribute to a broader understanding of the neurocognitive phenotype associated with 22q11.2DS.A Síndrome da Deleção 22q11.2 (SD22q11.2), microdeleção cromossômica mais frequente em humanos, é associada a um fenótipo neurocognitivo muito heterogêneo. Uma das principais características do espectro da síndrome é a variabilidade intelectual, que abrange de desempenho médio a deficiência intelectual, bem como discrepâncias entre Quociente de Inteligência Verbal e de Quociente de Inteligência de Execução, com maior prejuízo nas tarefas não verbais. O presente estudo teve por objetivo investigar aspectos do desempenho intelectual de uma amostra brasileira de 21 crianças e adolescentes diagnosticados com SD22q11.2, com base nos indicadores da Wechsler Intelligence Scale for Children – 4th edition. As amostras foram analisadas considerando diferenças entre os índices. Os resultados revelaram predomínio de Quociente de Inteligência Total na faixa limítrofe, entre 42 e 104, assim como discrepância significativa entre os índices de compreensão verbal e organização perceptual em 42% da amostra. No que concerne ao desempenho nos subtestes de forma isolada, um melhor resultado foi verificado em semelhanças, ao passo que cubos, raciocínio matricial, dígitos e sequência de números e letras foram os mais desafiadores. Esses achados indicam que uma avaliação abrangente de aspectos do desempenho intelectual contemplando as diversas medidas da Escala Wechsler de Inteligência pode contribuir para uma compreensão mais ampla do fenótipo neurocognitivo associado à SD22q11.2Núcleo de Editoração - PUC-Campinas2023-02-14info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://periodicos.puc-campinas.edu.br/estpsi/article/view/7406Psychological Studies; Vol. 36 (2019): Estudos de Psicologia (Campinas)Estudos de Psicologia; Vol. 36 (2019): Estudos de Psicologia (Campinas)Estudos de Psicologia; v. 36 (2019): Estudos de Psicologia (Campinas)1982-0275reponame:Estudos de Psicologia (Campinas)instname:Pontifícia Universidade Católica de Campinas (PUC-CAMPINAS)instacron:PUC_CAMPenghttps://periodicos.puc-campinas.edu.br/estpsi/article/view/7406/4958Copyright (c) 2023 Larissa Salustiano Evangelista PIMENTA, Cláudia Berlim de MELO, Diogo Cordeiro de Queiroz SOARES, Anelisa Gollo DANTAS, Maria Isabel MELARAGNO, Leslie Domenici KULIKOWSKI, Chong Ae KIMhttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessPIMENTA, Larissa Salustiano EvangelistaMELO, Cláudia Berlim deSOARES, Diogo Cordeiro de QueirozDANTAS, Anelisa GolloMELARAGNO, Maria Isabel KULIKOWSKI, Leslie DomeniciKIM, Chong Ae2023-02-14T16:22:35Zoai:ojs.periodicos.puc-campinas.edu.br:article/7406Revistahttps://seer.sis.puc-campinas.edu.br/seer/index.php/estudosPRIhttps://seer.sis.puc-campinas.edu.br/seer/index.php/estudos/oaisbi.ne_estpsi@puc-campinas.edu.br||estudosdepsicologia@puc-campinas.edu.br||psychologicalstudies@puc-campinas.edu.br1982-02750103-166Xopendoar:2023-02-14T16:22:35Estudos de Psicologia (Campinas) - Pontifícia Universidade Católica de Campinas (PUC-CAMPINAS)false |
dc.title.none.fl_str_mv |
Intellectual performance profi le of a sample of children and adolescents from Brazil with 22q11.2 Deletion Syndrome (22q11.2DS) based on the Wechsler Scale Perfi l de desempenho intelectual de uma amostra brasileira de crianças e adolescentes com Síndrome da Deleção 22q11.2 (22q11.2DS) com base na Escala Wechsler |
title |
Intellectual performance profi le of a sample of children and adolescents from Brazil with 22q11.2 Deletion Syndrome (22q11.2DS) based on the Wechsler Scale |
spellingShingle |
Intellectual performance profi le of a sample of children and adolescents from Brazil with 22q11.2 Deletion Syndrome (22q11.2DS) based on the Wechsler Scale PIMENTA, Larissa Salustiano Evangelista DiGeorge syndrome Genetics, behavioral Neuropsychology Wechsler Scales Síndrome de DiGeorge Genética comportamental Neuropsicologia Escalas de Wechsler |
title_short |
Intellectual performance profi le of a sample of children and adolescents from Brazil with 22q11.2 Deletion Syndrome (22q11.2DS) based on the Wechsler Scale |
title_full |
Intellectual performance profi le of a sample of children and adolescents from Brazil with 22q11.2 Deletion Syndrome (22q11.2DS) based on the Wechsler Scale |
title_fullStr |
Intellectual performance profi le of a sample of children and adolescents from Brazil with 22q11.2 Deletion Syndrome (22q11.2DS) based on the Wechsler Scale |
title_full_unstemmed |
Intellectual performance profi le of a sample of children and adolescents from Brazil with 22q11.2 Deletion Syndrome (22q11.2DS) based on the Wechsler Scale |
title_sort |
Intellectual performance profi le of a sample of children and adolescents from Brazil with 22q11.2 Deletion Syndrome (22q11.2DS) based on the Wechsler Scale |
author |
PIMENTA, Larissa Salustiano Evangelista |
author_facet |
PIMENTA, Larissa Salustiano Evangelista MELO, Cláudia Berlim de SOARES, Diogo Cordeiro de Queiroz DANTAS, Anelisa Gollo MELARAGNO, Maria Isabel KULIKOWSKI, Leslie Domenici KIM, Chong Ae |
author_role |
author |
author2 |
MELO, Cláudia Berlim de SOARES, Diogo Cordeiro de Queiroz DANTAS, Anelisa Gollo MELARAGNO, Maria Isabel KULIKOWSKI, Leslie Domenici KIM, Chong Ae |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
PIMENTA, Larissa Salustiano Evangelista MELO, Cláudia Berlim de SOARES, Diogo Cordeiro de Queiroz DANTAS, Anelisa Gollo MELARAGNO, Maria Isabel KULIKOWSKI, Leslie Domenici KIM, Chong Ae |
dc.subject.por.fl_str_mv |
DiGeorge syndrome Genetics, behavioral Neuropsychology Wechsler Scales Síndrome de DiGeorge Genética comportamental Neuropsicologia Escalas de Wechsler |
topic |
DiGeorge syndrome Genetics, behavioral Neuropsychology Wechsler Scales Síndrome de DiGeorge Genética comportamental Neuropsicologia Escalas de Wechsler |
description |
The 22q11.2 Deletion Syndrome (22q11.2DS), the most common human chromosome microdeletion syndrome, is associated with a very heterogeneous neurocognitive phenotype. One of the main characteristics of the syndrome spectrum is the intellectual variability, which encompasses average performance and intellectual disability and discrepancies between Verbal Intelligence Quotient and Performance Verbal Intelligence Quotient, with greater impairment in nonverbal tasks. The present study aimed at investigating the intellectual performance aspects of a 21children and adolescents sample from Brazil who had been diagnosed with 22q11.2DS, based on the Wechsler Intelligence Scale for Children - 4th edition. The samples were reviewed considering the differences between indices. The results revealed an Full Scale Intelligence Quotient predominant in the borderline range (42 to 104) and a significant discrepancy between the indices of Verbal Comprehension and Perceptual Reasoning in 42% of the sample. With regard to the performance in the subtests alone, a better performance was found in Similarities, whereas block design, matrix reasoning, digit span and letter-number sequencing subtests were the most challenging. These findings indicate that a comprehensive assessment of intellectual performance aspects covering the different measures of the Wechsler Intelligence Scale may contribute to a broader understanding of the neurocognitive phenotype associated with 22q11.2DS. |
publishDate |
2023 |
dc.date.none.fl_str_mv |
2023-02-14 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://periodicos.puc-campinas.edu.br/estpsi/article/view/7406 |
url |
https://periodicos.puc-campinas.edu.br/estpsi/article/view/7406 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://periodicos.puc-campinas.edu.br/estpsi/article/view/7406/4958 |
dc.rights.driver.fl_str_mv |
https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Núcleo de Editoração - PUC-Campinas |
publisher.none.fl_str_mv |
Núcleo de Editoração - PUC-Campinas |
dc.source.none.fl_str_mv |
Psychological Studies; Vol. 36 (2019): Estudos de Psicologia (Campinas) Estudos de Psicologia; Vol. 36 (2019): Estudos de Psicologia (Campinas) Estudos de Psicologia; v. 36 (2019): Estudos de Psicologia (Campinas) 1982-0275 reponame:Estudos de Psicologia (Campinas) instname:Pontifícia Universidade Católica de Campinas (PUC-CAMPINAS) instacron:PUC_CAMP |
instname_str |
Pontifícia Universidade Católica de Campinas (PUC-CAMPINAS) |
instacron_str |
PUC_CAMP |
institution |
PUC_CAMP |
reponame_str |
Estudos de Psicologia (Campinas) |
collection |
Estudos de Psicologia (Campinas) |
repository.name.fl_str_mv |
Estudos de Psicologia (Campinas) - Pontifícia Universidade Católica de Campinas (PUC-CAMPINAS) |
repository.mail.fl_str_mv |
sbi.ne_estpsi@puc-campinas.edu.br||estudosdepsicologia@puc-campinas.edu.br||psychologicalstudies@puc-campinas.edu.br |
_version_ |
1799126018447900672 |